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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Single Cell RNA Sequencing Identifies Primarily Terminal Effector and Exhausted CD8+T Cells in Chronically Rejected Human Kidney Allografts

    S. G. Yi1, D. Zou1, Y. Dai2, Z. Zhao2, W. Chen1, A. Gaber1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX, 2School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX

    *Purpose: Chronic renal allograft rejection often leads to irreversible damage, despite intensification of immunosuppression (ISN). T cell phenotypes in this clinical setting are not well…
  • 2022 American Transplant Congress

    Ex Vivo Liver Resection and Autotransplantation – Should It Be Used More Frequently?

    J. Weiner1, A. Griesemer1, A. Hemming2, D. Levi3, T. Beduschi4, R. Matsumoto1, A. Mathur1, J. Emond1, T. Kato1

    1Columbia University Irving Medical Center, New York, NY, 2University of Iowa, Iowa City, IA, 3Atrium Health, Charlotte, NC, 4University of Florida, Gainesville, FL

    *Purpose: Ex vivo liver resection expands the limits of resectability for advanced liver tumors but remains underutilized due to concerns about technical complexity and vascular…
  • 2022 American Transplant Congress

    Renal Graft Outcomes in Simultaneous Heart-Kidney Transplantation

    K. Okumura, S. Ohira, M. Kai, K. Wolf, A. L. Gass, D. Spielvogel, N. Singh, D. Glicklich, D. John, T. Diflo, S. Lansman, S. Nishida, A. Dhand

    Westchester Medical Center / New York Medical College, Valhalla, NY

    *Purpose: Simultaneous heart and kidney transplantation (SHKT) has increased steadily in United States Previously it was shown that SHKT is associated with benefits in overall…
  • 2022 American Transplant Congress

    Covid-19 in Pediatric Kidney Transplant: A Follow-Up Report of the Improving Renal Outcomes Collaborative

    C. Varnell, L. Harshman, M. Seifert, D. Hooper

    Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: To date studies of children with a kidney transplant and COVID-19 are limited. The Improving Renal Outcomes Collaborative (IROC) is a learning health network…
  • 2022 American Transplant Congress

    Rhesus-Primatized Mouse Model Generated Using Transgenic Immunodeficient Mice

    C. Little1, W. J. Haynes1, L. Huang1, C. Daffada1, K. B. Wolfe2, E. Perrin2, J. A. Simpson1, J. A. Kropp Schmidt2, H. M. Hinkle2, L. T. Keding2, R. T. Behrens2, D. T. Evans2, D. Kaufman1, J. A. Thomson2, T. G. Golos2, M. Brown1

    1Surgery, University of Wisconsin, Madison, WI, 2University of Wisconsin, Madison, WI

    *Purpose: To develop a translational primatized mouse model, akin to humanized mice, that allows for high-throughput in vivo experimentation to augment non-human primate pre-clinical studies.*Methods:…
  • 2022 American Transplant Congress

    Escalating Waitlist Mortality Above MELD 40: A Rationale to Uncap MELD 3.0?

    A. Kwong, A. Mannalithara, W. Kim

    Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA

    *Purpose: MELD 3.0 is a recently proposed model that improves upon MELD-Na, incorporating sex and albumin as additional variables, updating existing coefficients and adding relevant…
  • 2022 American Transplant Congress

    Experience Using Intra-Operative Dialysis in Surgically Complex Liver Transplantation

    M. Palascak1, D. Arango1, S. Yockelson1, J. Koveleskie1, D. Ganier1, A. Cohen2, H. Bohorquez2

    1Anesthesiology, Ochsner, New Orleans, LA, 2Surgery, Ochsner, New Orleans, LA

    *Purpose: At our high-volume center, we often perform liver transplantation (LT) on surgically complex patients that includes re-transplantation, prior open liver resection, bariatric surgeries, extensive…
  • 2022 American Transplant Congress

    Pre-Emptive Rituximab Use for Epstein-Barr Virus (EBV) Viremia in Cardiothoracic Solid Organ Transplant Recipients

    B. Astorga, A. Loethen, L. Potter

    University of Chicago Medicine, Chicago, IL

    *Purpose: EBV viremia is associated with potentially life-threatening post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. The utility of rituximab for treating EBV viremia in…
  • 2022 American Transplant Congress

    The Impact of Soluble Human Leukocyte Antigen (HLA) on Renal Antibody-Mediated Rejection (AMR) After Simultaneous Liver Kidney Transplantation (SLKT)

    H. Me1, A. Jaramillo1, D. Ramon1, L. G. Olsen1, R. Heilman1, H. Khamash1, T. Mohanakumar2, R. Ravichandran2

    1Mayo Clinic, Phoenix, AZ, 2St. Joseph's Hospital and Medical Center, Phoenix, AZ

    *Purpose: The lower incidence of AMR and higher incidence of rejection-free grafts survival in SLKT recipients as compared to kidney transplant recipients have been clearly…
  • 2022 American Transplant Congress

    Ethnic Variation in Adult and Pediatric Liver Transplantation

    N. Kemmer1, M. Malespin1, S. Agrawal1, R. Syed1, K. Alkhalloufi1, B. Alkurdi1, C. Albers1, J. Buggs2

    1Tampa General Hospital, Tampa, FL, 2Transplant Surgery, Tampa General Hospital, Tampa, FL

    *Purpose: Despite several policy reforms over the years, disparities in the access to solid organ transplantation continues to exist remains a significant barrier to liver…
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