Am J Transplant, Volume 22, Suppl 3 Archives - Page 95 of 190 - ATC Abstracts

2022 American Transplant Congress
Interaction Between Financial Barriers and Other Motivators, Barriers, and Facilitators of Living Organ Donation
A. R. Smith¹, R. J. Mandell¹, M. E. Helmuth¹, N. P. Goodrich¹, J. B. Wiseman¹, K. A. Gifford², M. A. Fava¹, A. O. Ojo³, R. M. Merion¹, A. K. Mathur⁴
¹Arbor Research Collaborative for Health, Ann Arbor, MI, ²American Society for Transplant Surgeons, Arlington, VA, ³University of Kansas Medical Center, Kansas City, KS, ⁴Mayo Clinic, Phoenix, AZ
*Purpose: Our objective was to assess how financial barriers to living donation interact with other motivators, barriers, and facilitators during the decision-making process.*Methods: Data were…
2022 American Transplant Congress
Effect of Micafungin Bridging on Prevention of Invasive Candidiasis Post Lung Transplantation
C. Baladad¹, M. Converse¹, K. DeSear¹, S. Karimi¹, E. Rubido¹, G. El Helou², T. Pasley¹
¹Pharmacy, University of Florida Health, Shands, Gainesville, FL, ²Infectious Diseases, University of Florida Health, Shands, Gainesville, FL
*Purpose: This study aims to determine the effect of micafungin, added as a bridging agent to azole antifungal prophylaxis, in lung transplantation patients with positive…
2022 American Transplant Congress
Use of De Novo mTOR Inhibitors in Highly Sensitized Kidney Transplant Recipients
J. Bastos¹, T. Freesz², C. Bisi³, C. Marinho², A. Pires², V. Colares³, R. Neto², G. Ferreira²
¹Tranplant Unit, Santa Casa De Misericordia De Juiz de Fora, Juiz de Fora, Brazil, ²Transplant Unit, Santa Casa De Misericórdia De Juiz de Fora, Juiz de Fora, Brazil, ³Tranplant Unit, Santa Casa De Misericórdia De Juiz de Fora, Juiz de Fora, Brazil
*Purpose: mTOR inhibitors (mTORi) allow calcineurin-inhibitor reduction without loss of efficacy and may improve allograft-transplant outcomes. However, the safety of this protocol in high-immunological risk…
2022 American Transplant Congress
Developing A Tool To Assess Psychosocial Determinants Of Health And Quality Of Life In Pediatric Liver Transplant Patients
C. R. Christmann¹, S. Rath², S. Sakhuja³, N. Galvan²
¹Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine, Houston, TX, ³Baylor College of Medicine, Sugar Land, TX
*Purpose: Psychosocial assessment prior to liver transplantation is essential to ensure that caregivers and pediatric patients are adequately prepared for this complex process. There are…
2022 American Transplant Congress
Increased Risk for Allograft Loss in African American Kidney Transplant Recipients After Biopsy for Chronic Allograft Dysfunction
C. R. Dorr¹, B. Wu², B. Guo², W. Guan², D. Schladt¹, S. Elmer¹, G. Crary³, G. Onyeaghala¹, W. Oetting², G. Agarwal⁴, R. B. Mannon⁵, P. Jacobson², A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Medicine, University of Nebraska Medical Center, Omaha, NE
*Purpose: Chronic allograft dysfunction (CGD) is the first sign of a “troubled kidney”. CGD was defined as >25% increase in serum creatinine relative to a…
2022 American Transplant Congress
Single Cell Transcriptomics Reveal Allograft Immune Cell Patterns Associated with Histological Features of Acute Cellular Rejection in Liver Transplantation
L. Tran¹, A. Zahorchak¹, C. Macedo¹, T. Tabib², F. Lakkis³, A. Humar¹, D. Metes¹, A. Thomson¹
¹Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ²University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Pittsburgh Medical Center - Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Development of successful tolerance induction strategies using immune cell-based therapies in transplantation depends on improved understanding of the local intra-graft cellular milieu that underlies…
2022 American Transplant Congress
Antibody Response and Molecular Graft Surveillance in Kidney Transplant Recipients Following Sars-CoV-2 Vaccination
N. M. Ali¹, J. Miles², S. Mehta¹, V. Tatapudi¹, Z. Stewart¹, B. Lonze¹, M. Mangiola¹, C. DiMaggio¹, E. Weldon¹, I. Saeed¹, J. Leonard¹, R. Herati¹, J. Thomas¹, J. Michael¹, C. Hickson¹, K. Cartiera¹, R. Montgomery¹
¹Transplant Institute, NYU Langone Health, New York, NY, ²CareDx, Brisbane, NY
*Purpose: Preliminary studies suggest that kidney transplant recipients (KTRs) show diminished humoral responses to SARS-CoV-2 vaccination. Although reports of allograft rejection after SARS-CoV-2 vaccination have…
2022 American Transplant Congress
Inflammation After Kidney Transplantation Is Associated With Overall- And Death-censored Graft Loss
T. F. Heldal, T. Jenssen, A. Hartmann, K. Heldal, A. Asberg
Department of Transplantational Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: Early graft loss after kidney transplantation (KT) is mainly a result of acute rejection, while long-term graft loss episodes are often dependent on multifactorial…
2022 American Transplant Congress
Single Blind Randomized Controlled Trial Comparing BNT162b2 Vs JNJ-78436735 Vaccine As An Additional Dose After Two Doses Of BNT162b2 Vaccine In Solid Organ Transplant (SOT) Recipients
Y. Natori¹, E. Martin², A. Mattiazzi³, J. Bini Viotti¹, K. S. Ortecho⁴, S. Pallikkuth⁵, S. Anjan¹, J. Simkins¹, G. Guerra³
¹Department of Medicine, Division of Infectious Diseases, University of Miami, Miami, FL, ²Department of Medicine, Division of Hepatology, University of Miami, Miami, FL, ³Department of Medicine, Division of Nephrology, University of Miami, Miami, FL, ⁴Miami Transplant Institute, Jackson Health System, Miami, FL, ⁵University of Miami, Miami, FL
*Purpose: Even though a high efficacy and immunogenicity of COVID-19 vaccines have been reported in the general population, vaccine immunogenicity is suboptimal in SOT recipients…
2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis
J. McDaniels¹, A. Shetty¹, C. Kuscu², C. Kuscu², T. Rousselle¹, E. Bardhi¹, C. Drachenberg¹, M. Talwar², J. Eason², T. Muthukumar³, D. Maluf¹, V. Mas¹
¹University of Maryland Baltimore, Baltimore, MD, ²UTHSC, Memphis, TN, ³Weill Cornell Medicine, New York, NY
*Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…