Am J Transplant, Volume 22, Suppl 3 Archives - Page 91 of 190 - ATC Abstracts

2022 American Transplant Congress
Characterisation of Kidney-Specific Extracellular Vesicles During Isolated Organ Normothermic Machine Perfusion
J. Ashcroft¹, T. L. Williams², T. R. Elliott¹, A. Marton¹, S. A. Hosgood¹, M. L. Nicholson¹, V. Kosmoliaptsis¹
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom, ²Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
*Purpose: Introduction: Normothermic machine perfusion (NMP) can evaluate and recondition deceased-donor kidneys but accurate biomarkers are needed to assess organ quality and to predict post-transplant…
2022 American Transplant Congress
Comparison of IGG and IGM Type B Cell Receptor-Mediated MTOR Phosphorylation Signal
Y. Matsuda
Division of Transplant Immunology, Division of Transplant Immunology, Tokyo, Japan
*Purpose: IgG and IgM memory B cells (mBCs) corresponding donor-specific antigen are closely involved in the activation of humoral immunity against transplanted grafts. Therefore, it…
2022 American Transplant Congress
Revisiting Late Graft Loss or Death in Pediatric Liver Transplantation Through Analysis of the SPLIT Database
J. E. Squires¹, J. Bilhartz², K. Soltys¹, E. Hafberg³, G. V. Mazariegos¹, N. Gupta⁴, R. Anand⁵, S. G. Anderson⁵, T. Miloh⁶
¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²C. S. Mott Children's Hospital, Ann Arbor, MI, ³Vanderbilt University School of Medicine, Nashville, TN, ⁴Children's Healthcare of Atlanta and Emory University School of Medicine, Attlanta, GA, ⁵The Emmes Company, Rockville, MD, ⁶University of Miami, Miami, FL
*Purpose: With advances in surgical techniques, medical management, and more equitable allocation systems, children who receive a liver transplant today can expect remarkable outcomes early…
2022 American Transplant Congress
The Limited Role of Liver Transplantation in Porto-Pulmonary Hypertension Pathology
J. Doi¹, M. Fujiki², S. Chaudhry¹, T. Diago¹, F. Aucejo¹, C. Kwon¹, B. Eghtesad³, C. Miller⁴, C. Quintini⁵, K. Hashimoto¹
¹Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic Foundation, Cleveland, OH, ³The Cleveland Clinic, Cleveland, OH, ⁴The Cleveland Clinic, Bratenahl, OH, ⁵Cleveland Clinic, Beachwood, OH
*Purpose: Portopulmonary hypertension (POPH) refers to pulmonary artery hypertension (PH) as a consequence of portal hypertension with or without liver disease. Previous studies used pulmonary…
2022 American Transplant Congress
Defining New Arterial and Arteriolar Lesions Accompanying Transplant Glomerulopathy: Potential Additions to the Histologic Assessment of ABMR
A. Perkowska-Ptasinska¹, D. Deborska-Materkowska², M. Ciszek³, M. Myslak⁴, J. Chang⁵, J. Reeve⁶, P. Halloran⁷
¹Pathology, Medical University of Warsaw, Warsaw, Poland, ²Transplantation Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland, ³Immunology, Transplantation Medicine and Internal Diseases, Medical University of Warsaw, Warsaw, Poland, ⁴Infectious Diseases, Hepatology and Liver Transplantation, Pomeranian Medical University, Szczecin, Poland, ⁵Alberta Transplant Applied Genomics Center, Edmonton, AB, Canada, ⁶Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ⁷Pathology, Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada
*Purpose: Transplant glomerulopathy (TG) results from chronic endothelial injury most commonly related to ABMR. Surprisingly, except for PTC, the relation between TG and other vascular…
2022 American Transplant Congress
Performance of Donor Derived Cell Free DNA (dd-cfDNA) in Diagnosing Subclinical and Clinical Acute Rejection in Kidney Transplant Recipients
T. Cober, P. West-Thielke, C. Miller, N. Grund, M. Altrich, A. Sutton, R. Sinha, M. Miller, S. Kleiboeker, J. Weems
Eurofins, Framingham, MA
*Purpose: The aim of this study was to examine the performance of Viracor TRAC donor derived cell free DNA (dd-cfDNA) in for-cause biopsies as well…
2022 American Transplant Congress
Evaluation of Technical Bladder Complications in Kidney Transplantation Recipients with a Prolonged Dialysis History
S. M. Zielsdorf, K. Kushwaha, C. Goldbeck, S. Martin, Y. Kwon, K. Etesami, J. Kim, J. Emamaullee, S. Zielsdorf
University of Southern California, Los Angeles, CA
*Purpose: The kidney transplant (KT) waiting list continues to expand, resulting in prolonged dialysis times of >8 years prior to transplantation in some regions. The…
2022 American Transplant Congress
De Novo Anti-Brush Border Antibody Disease in a Kidney Transplant Recipient
P. Yenebere, D. Ibrahim, T. Nadasdy, R. Daloul
Ohio State University, Columbus, OH
*Purpose: Anti-brush border antibody (ABBA) disease is very rare, characterized by tubulointerstitial damage caused by autoantibodies against LDL receptor-related protein 2 (LRP2) in the proximal…
2022 American Transplant Congress
Characterization Of Local Antibody Responses In Human Cardiac Allograft Vasculopathy
S. B. See¹, L. J. Stanton¹, P. Roy¹, S. Mashiko¹, E. R. Vasilescu², C. C. Marboe², M. Szabolcs², M. V. Habal³, M. Farr³, S. Restaino³, Y. Naka⁴, D. M. Mancini⁵, J. C. Madsen⁶, R. G. King⁷, E. P. Kransdorf⁸, E. Zorn¹
¹CCTI, Columbia University Irving Medical Center, New York, NY, ²Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, ³Medicine, Columbia University Irving Medical Center, New York, NY, ⁴Surgery, Columbia University Irving Medical Center, New York, NY, ⁵Cardiology, Icahn School of Medicine, New York, NY, ⁶CTS, Massachusetts General Hospital, Boston, MA, ⁷Microbiology, University of Alabama, Birmingham, AL, ⁸Cedars-Sinai Heart Institute, Los Angeles, CA
*Purpose: Cardiac allograft vasculopathy (CAV) is the leading cause of heart graft recipient mortality after five years post-transplant. A major hurdle to improving outcomes is…
2022 American Transplant Congress
Immunotherapy Before Solid Organ Transplantation: An International Transplant Community-Focused Survey
T. Ivanics¹, M. P. Claasen¹, D. Al-Adra², G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada
*Purpose: The use of immunotherapy for cancer has increased and is expected to continue to grow. The outcomes after solid organ transplantation (SOT) in patients…