2022 American Transplant Congress
Leveraging Car T Cells To Achieve Desensitization And Enable Transplantation
UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA
*Purpose: Pre-existing allo-antibodies (allo-Abs), that preclude transplant due to the risk of hyperacute rejection, lead to prolonged wait times and high mortality rates. Current desensitization…2022 American Transplant Congress
The Effect of Bariatric Surgery Pre-Transplant on Renal Transplant Outcomes
Surgery, McGill, Montreal, QC, Canada
*Purpose: We compared post-transplant outcomes in patients with morbid obesity undergoing pre-transplant bariatric surgery to non-obese and obese patients without bariatric surgery.*Methods: Adult recipients of…2022 American Transplant Congress
Regional Variation in Early Effects of Acuity Circle-Based Liver Allocation
*Purpose: Liver allocation in the United States was updated on February 4th, 2020, byintroducing the acuity circle (AC)-based model. This study evaluated the early effects…2022 American Transplant Congress
Impact of Long Agonal Duration on Outcomes After Donation After Circulatory Death Lung Transplantation: An Analysis of the United Network of Organ Sharing Database
Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Lung transplantation (LTx) using donation after circulatory death (DCD) donors has been well established, however, previous investigators have focused on time from withdrawal of…2022 American Transplant Congress
Passenger Lymphocyte Syndrome Presented as Hemolytic Anemia After Small Bowel Transplantation: A Case Report
*Purpose: The passenger lymphocyte syndrome (PLS) induces hemolytic anemia after minor ABO mismatched organ transplantation. We experienced a case of PLS with hemolysis after small…2022 American Transplant Congress
Analysis of Tissue and Effluent Damage Associated Molecular Patterns Following Hypothermic Oxygenated Machine Perfusion vs Static Cold Storage in Liver Transplantation
Transplant Surgery, Rutgers New Jersey Medical School, Newark, NJ
*Purpose: Hypothermic Oxygenated Machine Perfusion (HMP-O2) results in decreased ischemia/reperfusion injury (IRI) after liver transplantation; however, the molecular pathways of protection are largely unexplored. In…2022 American Transplant Congress
Intrinsic DEPTOR Activity Modulates Treg Subset Differentiation
*Purpose: We have previously reported that DEPTOR activity within CD4+Foxp3+ Tregs increases immunomodulation following transplantation. DEPTOR functions by both stabilization of Foxp3 expression through epigenetic…2022 American Transplant Congress
Influence of Immunosuppressive Drugs on Nk Cells in Therapeutic Drug Exposured
*Purpose:Natural killer (NK) cells as part of the innate immune system are residing in the liver and are considered to be main regulators in alloimmune…2022 American Transplant Congress
Risk Factors for Extubation Failure Post- Lung Transplantation
*Purpose: Extubation delays following lung transplantation can result in delirium, deconditioning, infections, and increased hospital length of stay. Risk stratifying patients for extubation failure may…2022 American Transplant Congress
Plasmapheresis Dependent AT1R Antibody Associated Recurrent FSGS After Living Donor Kidney Transplantation
Transplant Nephrology, Augusta University - Medical College of Georgia, Augusta, GA
*Purpose: Antibodies against Angiotensin II type 1 receptors (AT1R-Abs) may predispose to podocyte injury, glomerular endotheliosis and proteinuria. The management of AT1R-Ab associated recurrent FSGS…
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