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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients

    R. Gordon1, K. Dewey1, R. Jariwala1, B. Yen1, J. Kukreja2, S. Hays2, J. Singer2, R. Florez1

    1Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA

    *Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…
  • 2022 American Transplant Congress

    A Multi-Center Study Assessing the Association of Frailty with Infection in Kidney Transplant Recipients

    M. Malinis1, M. Abidi2, E. Benamu2, N. Jakharia3, N. Law4, R. Sigler4, R. Nog5, S. Olivier5, S. Taimur6, N. Theodoropoulos7, J. Schaenman8

    1Yale University School of Medicine, New Haven, CT, 2University of CO, Aurora, CO, 3Stanford, Palo Alto, CA, 4UCSD, San Diego, CA, 5Westchester Med Ctr, Westchester, NY, 6Mount Sinai SOM, New York, NY, 7Univ of MA, Worcester, MA, 8UCLA, Los Angeles, CA

    *Purpose: Frailty is a multi-dimensional characterization of decreased reserve and diminished response to stressors in older adults. Frailty at the time of transplant has been…
  • 2022 American Transplant Congress

    HLA-Specific IgD/CD27 Double Negative B Cell Frequency Assessed by a Novel Multiplex Bead-Based Assay Predicts Rejection in Kidney Transplant Recipients

    Z. Ilyas1, A. Akl2, D. Pinelli1, L. Gallon3, A. Tambur1, M. Ansari4

    1Northwestern University, Chicago, IL, 2Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia, 3Northwestern Univ NMFF, Chicago, IL, 4Medicine, Northwestern University, Chicago, IL

    *Purpose: Recipients with sensitization to HLA defined by a high percentage of Panel Reactive Antibodies (PRA) or Donor-specific anti-HLA antibodies (DSA) are at higher immunologic…
  • 2022 American Transplant Congress

    Synergistic Effect of CXCR5+CD8+ TAb-supp Cell Adoptive Cell Therapy and mTOR Inhibition (but Not Calcineurin Inhibition) in Suppressing Alloantibody Following Kidney Transplant in Mice

    J. L. Han1, J. M. Zimmerer1, Q. Zeng2, S. Chaudhari1, C. K. Breuer2, G. L. Bumgardner1

    1Dept. of Surgery, The Ohio State University, Columbus, OH, 2Center for Regen. Med., The Research Institute at Nationwide Children's Hospital, Columbus, OH

    *Purpose: We have reported that CXCR5+CD8+TAb-supp cells mediate suppression of alloantibody (alloAb) production and prolong graft survival in both hepatocellular and kidney transplant (KTx) mouse…
  • 2022 American Transplant Congress

    Compliance with OPTN Infectious Disease Testing

    L. Irwin

    Massachusetts General Hospital, Boston, MA

    *Purpose: Effective 3/1/21 OPTN policy requires all transplant recipients to have pre-transplant and post-transplant infectious disease testing performed at specific intervals: upon admission and prior…
  • 2022 American Transplant Congress

    Treading the Paradigm Shift: A Single Center Comparative Study of Outcomes Between Pre-Emptive and Early Kidney Transplant with Non Pre-Emptive Kidney Transplant Recipients Innational Kidney and Transplant Institute

    E. U. Go, L. Baloloy

    Organ Transplantation and Vascular Surgery, National Kidney and Transplant Institute, Quezon City, Philippines

    *Purpose: To compare the 3-year outcome of pre-emptive and early kidney transplant recipients versus non pre-emptive recipients in our institution from January 2013 to December…
  • 2022 American Transplant Congress

    Cortex Recipient Weight Ratio is a Predictor for Short-Term Renal Function After Living Donor Kidney Transplant

    K. Takahashi1, K. Furuya1, J. Usui2, T. Kimura3, S. Fukuda4, A. Hoshi3, T. Yoshino3, H. Nishiyama3, T. Oda1, K. Yamagata2

    1Gastrointestinal and Hepatobiliary Pancreatic Surgery, University of Tsukuba, Tsukuba, Japan, 2Nephrology, University of Tsukuba, Tsukuba, Japan, 3Urology, University of Tsukuba, Tsukuba, Japan, 4Nursing, University of Tsukuba, Tsukuba, Japan

    *Purpose: Renal function early after living donor kidney transplant (LDKT) depends on “nephron mass” in the renal graft, and “nephron mass” can be quantified as…
  • 2022 American Transplant Congress

    Identification of a Donor Kidney with Heterozygous COL4A3-related Alport Syndrome in a Homozygous Recipient Highlighting the Importance of Genetic Testing

    K. Alrejjal1, U. Abdullatif1, L. Beretich2, H. Tabriziani2, A. Abdellatif3

    1CLS Health, Webster, TX, 2Natera, Inc., Austin, TX, 3Baylor College of Medicine, Houston, TX

    *Purpose: Selection of an appropriate donor for kidney transplantation can mitigate the risk of rejection and increase the chances of graft survival. While immunologic matching…
  • 2022 American Transplant Congress

    Causal Factors and Clinical Impact of Urinary Tract Infections in Renal Transplanted Patients: An Observational Retrospective Study

    C. Alfieri, F. Tripodi, D. Cresseri, M. Gandolfo, M. Campise, A. Regalia, P. Messa, G. Castellano

    Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico Milano, Milan, Italy

    *Purpose: This study aims to examine the etiology of urinary tract infections (UTIs) in a cohort of KTxps, trying to identify their potential predisposing factors…
  • 2022 American Transplant Congress

    A More Equitable Transplant Evaluation: What Patient-Level Factors Impact Time to Kidney Transplant Evaluation Completion?

    T. Menser, M. J. Hobeika, E. Hsu, L. W. Moore, A. D. Waterman, A. O. Gaber, R. J. Knight

    Houston Methodist, Houston, TX

    *Purpose: The kidney transplant evaluation process can take months or years to complete depending on patient health status and level of engagement. This study examines…
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