ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pancreas Transplants Outcomes in Diabetes Mellitus Type 1 and Type 2 in the 21st Century: Are They Two Different Populations?

    M. Merzkani1, H. Murad2, M. Wang1, V. Hu1, M. Ji3, Y. Al-Hosni1, O. Alzahabi1, M. Zayed1, J. Wellen4, K. Lentine5, S. Chang6, T. Alhamad7

    1Washington University, St Louis, MO, 2Washington University in St Louis, Chesterfield, MO, 3Washington University in St. Louis School of Medicine, Saint Louis, MO, 4Washington University School of Medicine, Saint Louis, MO, 5SLU, St Louis, MO, 6Surgery, Washington University School of Medicine, Saint Louis, MO, 7Washington University School of Medicine at St. Louis, Saint Louis, MO

    *Purpose: Pancreas alone transplant (PT) has been associated with decreased progression and regression of microvascular and macrovascular complications. In this current era of standardized immunosuppression,…
  • 2022 American Transplant Congress

    Estimating the Effect of Increased Donor Heart Ischemic Time on Post-Transplant Survival Using Instrumental Variables

    G. Ran1, K. Lazenby1, N. Narang2, W. F. Parker3

    1Pritzker School of Medicine, University of Chicago, Chicago, IL, 2Department of Medicine, University of Illinois-Chicago, Chicago, IL, 3Department of Medicine, University of Chicago, Chicago, IL

    *Purpose: Isolate the impact of organ ischemic time on post-transplant survival using the recent change in heart allocation policy as a natural experiment.*Methods: We examined…
  • 2022 American Transplant Congress

    Prospective Analysis of the Impact of Impella 5.5 Devices on HLA Antibody Development in Transplant Recipients

    K. Castro, J. Van Zyl, R. Doss, S. McKean, J. Russelia, A. Alam, M. Askar, S. Hall

    Heart and lung Transplant Research, Baylor University Medical Center, Dallas, TX

    *Purpose: Little is known about the development of Human Leukocyte Antigen antibodies with the use of the new Impella 5.5 temporary mechanical circulatory assist device.*Methods:…
  • 2022 American Transplant Congress

    The Paradox of Lifestyle – Related Liver Disease: ASH and NASH

    N. Kemmer1, J. Buggs2

    1Transplant Hepatology, Tampa General Hospital, Tampa, FL, 2Transplant Surgery, Tampa General Hospital, Tampa, FL

    *Purpose: In the last decade, the burden of lifestyle-related chronic disease has been on the rise and is considered a growing serious public health concern.…
  • 2022 American Transplant Congress

    Circulating Donor-Derived Cell-Free DNA: A Novel Non-Invasive Biomarker for Immune Surveillance in Vascularized Composite Allotransplantation

    W. J. Rifkin1, J. Trilles1, P. S. Rabbani1, O. C. Onuh1, B. E. Gelb2, D. J. Ceradini1, E. D. Rodriguez1

    1Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY, 2Transplant Institute, NYU Langone Health, New York, NY

    *Purpose: The purpose of this study is to evaluate whether circulating donor-derived cell-free DNA (dd-cfDNA) could be used as a noninvasive biomarker to detect rejection…
  • 2022 American Transplant Congress

    Higher Hepatocellular Carcinoma Tumor Burden Score is Associated with Grater Liver Transplant Survival Benefit

    H. Liu1, W. Zhang2, M. Di3, H. Lee4, R. Cruz1, X. Wang2, C. Kaltenmeier1, A. Thompson1, D. Reddy1, E. Ashwat1, M. D'Alesio1, S. Lebowitz1, S. Tohme1, D. Geller1, A. Tevar1, C. Hughes1, A. Humar1, J. Behari5, R. Bataller5, S. Hariharan5, M. Molinari1

    1Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, 2Mathematics and Statistics, University of Arkansas at Little Rock, Little Rock, AR, 3Medicine, Medical Oncology, Yale University, New Haven, CT, 4Biostatistics, Massachusetts General Hospital, Boston, MA, 5Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Liver transplantation(LT) is the best treatment option for early-stage hepatocellular carcinoma(HCC) and cirrhosis. However, patients with various tumor burdens receive identical listing priority, despite…
  • 2022 American Transplant Congress

    Cell-Free DNA Concentration in Hypothermic Machine Perfusate is a Potential Rapid Marker for Kidney Graft Quality

    S. Duarte1, M. Willman1, V. Boominathan1, D. Lewis1, W. De Faria1, G. Vrakas1, A. El-Hinnawi1, T. Beduschi1, N. Battula2, A. Zarrinpar1

    1University of Florida, Gainesville, FL, 2University of Oklahoma Medical College, Oklahoma City, OK

    *Purpose: The successful use of hypothermic machine perfusion (HMP) as a clinical modality for graft preservation prior to kidney transplantation (KTx) has generated a demand…
  • 2022 American Transplant Congress

    Metabolic Outcomes After Simultaneous Pancreas Kidney Transplant from Donation After Circulatory Death Donors – The UK Registry Analysis

    J. Gopal, A. McLean, A. Muthusamy

    Imperial College Renal and Transplant Center, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: DCD pancreas transplantation is established as a valuable cohort to expand the pancreas donor pool, with equivalent graft & patient survival compared to pancreases…
  • 2022 American Transplant Congress

    Is Pathologic AMR Grading Scale Associated with the Presence of Donor-Specific Antibodies?

    S. Kim, J. Patel, M. Kittleson, T. Singer-Englar, N. Patel, D. Chang, E. Kransdorf, D. Emerson, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Antibody-mediated rejection (AMR) has been defined by an expert pathology group in 2011 which resulted in the ISHLT pathologic AMR (pAMR) grading scale. The…
  • 2022 American Transplant Congress

    Bacterial Infections After Kidney Transplant Before and After the COVID-19 Pandemic

    A. Perez Gutierrez1, B. Juengel1, S. Krishnamoorthy2, P. J. Bachul1, P. Witkowski3, R. Barth3, J. Fung1

    1Department of Surgery, University of Chicago Medicine, Chicago, IL, 2Department of Medicine, University of Chicago Medicine, Chicago, IL, 3University of Chicago Medicine, Chicago, IL

    *Purpose: Infectious complications are a major cause of mortality and morbidity after kidney transplantation. During the COVID-19 pandemia there were several changes in the management…
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