ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Reduction of Discharge Opioid Prescriptions After Kidney Transplantation: A Quality Improvement Project

    A. W. Rogers, E. Rizk, J. T. Swan, S. G. Yi, M. Hobeika, R. R. McMillan, J. C. Krisl, H. Podder, A. O. Gaber, R. J. Knight

    Houston Methodist Hospital, Houston, TX

    *Purpose: Opioid use after kidney transplant has been linked to poorer outcomes, and unused prescriptions can lead to potential misuse. Historical prescribing practice at our…
  • 2022 American Transplant Congress

    MTOR Inhibition Acts Directly on Endothelial Cells to Induce Contact-Independent Immune-Modulation of Allo-Specific T Cell Activation

    H. Xu, L. Wang, V. A. Bendersky, Q. Gao, Q. Li, A. D. Kirk, H. Xu

    Duke University School of Medicine, Durham, NC

    *Purpose: Endothelial cells (ECs) form a barrier between vascularized organ allografts and host immunity and are known to provoke alloimmune responses. The mTOR inhibitor rapamycin…
  • 2022 American Transplant Congress

    Type 1 Innate Lymphoid Cells Are Critical Pro-Inflammatory Effector Cells in a Fatty Liver Mouse Model of Ischemia-Reperfusion Injury

    J. Kang, J. Liggett, K. Oza, Y. Cui, K. Loh, D. Kwon, B. Kallakury, T. Fishbein, W. Cui, K. Kahn, A. Kroemer

    MedStar Georgetown Transplant Institute, Washington, DC

    *Purpose: Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis through the production of key cytokine…
  • 2022 American Transplant Congress

    Liver Transplantation Outcomes for Budd-Chiari Syndrome in the MELD Era

    S. A. Alqahtani1, C. Schneider2, O. Sims3, A. Gurakar4, H. Tamim5, A. Bonder6, B. Saberi6

    1King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, 2The Institute for Translational Medicine and Therapeutics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 3School of Medicine, School of Public Health, School of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, 4Division of Gastroenterology & Hepatology, Johns Hopkins University, Baltimore, MD, 5Department of Internal Medicine, American University of Beirut, Beirut, Lebanon, 6Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    *Purpose: Budd Chiari syndrome (BCS) has a heterogeneous clinical presentations ranging from asymptomatic cases to fulminant liver failure with significant morbidly and mortality. Recent data…
  • 2022 American Transplant Congress

    Effect Of A Fourth Covid-19 Vaccine Dose On Omicron Variant Neutralization In Solid Organ Transplant Recipients

    A. Karaba, A. Abedon, J. Alejo, C. X. Qin, D. Warren, J. Ruff, T. Aytenfisu, T. S. Johnston, O. Akinde, A. Pekosz, S. Klein, A. Cox, D. Segev, A. Tobian, W. Werbel

    Johns Hopkins University, Baltimore, MD

    *Purpose: Humoral response to COVID-19 vaccines is attenuated in many solid organ transplant recipients (SOTRs), necessitating additional primary and booster vaccinations. The omicron variant demonstrates…
  • 2022 American Transplant Congress

    Locoregional Therapy for Hepatocellular Carcinoma Decreases Liver Transplant Waitlist Dropout and Mortality

    S. Weeks, T. Ishaque, A. Massie, D. Segev, E. King

    Johns Hopkins, Baltimore, MD

    *Purpose: Liver transplant candidates with hepatocellular carcinoma (HCC) risk tumor progression that may disqualify them from transplant eligibility while awaiting HCC exception points on the…
  • 2022 American Transplant Congress

    Excellent Long-Term Outcome of ABO-Incompatible Living Kidney Transplantation by Reduced-Session of Plasmapheresis of Desensitization Protocol

    Y. Ishiyama1, K. Tanabe2, T. Kanzawa2, K. Unagami2, H. Ishida2, T. Takagi2

    1Urology, Tokyo Women's Medical University Medical Center East, Arakawa, Japan, 2Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: Plasmapheresis (PE) is applied to ABO-incompatible living kidney transplantation (ABOi-LKT) in order to remove ABO blood type antibody to obtain the appropriate target levels.…
  • 2022 American Transplant Congress

    Growing Use of Perfusion for Heart, Liver, and Lung and Early Outcomes

    R. R. Goff1, K. Gauntt1, W. Cherikh1, E. D. Lease2, D. Klassen1

    1United Network for Organ Sharing, Richmond, VA, 2University of Washington, Seattle, WA

    *Purpose: In 2015 the OPTN began collecting data on perfusion for heart, liver, and lung deceased donors (DD) on the DD registration form. Since 2015,…
  • 2022 American Transplant Congress

    HDAC Inhibitors Suppress Endothelial Inflammation but Alter Identity

    N. M. Valenzuela

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    *Purpose: Histone modifications such as acetylation control gene expression. Histone deacetylases (HDACs) have been proposed as an attractive therapeutic approach to counteract detrimental gene expression,…
  • 2022 American Transplant Congress

    Sars-cov-2 Antibodies Transitions After Vaccination In Solid Organ Transplant Recipients: Multicenter Study In Japan

    K. Unagami1, M. Yoshikawa2, Y. Natori3, K. Omoto1, H. Ishida1, H. Date4, R. Imamura5, T. Ito4, K. Miyaji6, S. Takahara7, K. Yuzawa8, O. Satoko9, Y. Hirota10, H. Egawa1

    1Tokyo Women's Medical University, Tokyo, Japan, 2Kyoto Prefectural University of Medicine, Kyoto, Japan, 3University of Miami, Pinecrest, FL, 4Kyoto University, Kyoto, Japan, 5Dept. of Urology, Osaka Univ. Graduate School of Medicine, Suita, Japan, 6Renal Transplantation, Takatsuki General Hospital, Takatsuki, Japan, 7Kansai Medical Hospital, Toyonaka, Japan, 8Tranplantation Surgery, National Hospital Organization Mito Medical Center, Mito, Japan, 9Public Health, Osaka City University Graduate School of Medicine and Research Center for Infectious, Osaka City University Graduate School of Medicine, Osaka, Japan, 10Clinical Epidemiology Research Center, Miyama, Japan

    *Purpose: For purpose of SARS-CoV-2 infection control, vaccination was started in worldwide, however, low reactivity of antibody production after vaccination is a concern for solid…
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