ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    25-Year Risk of ESRD Among Living Kidney Donors

    J. Wainright1, A. Robinson1, A. Wilk1, D. Klassen2, W. Cherikh1, D. Stewart1

    1Research, UNOS, Richmond, VA, 2Office of the Chief Medical Officer, UNOS, Richmond, VA

    *Purpose: Previous research on post-donation ESRD in living kidney donors (LKDs) has been limited by short follow-up time, the small number of ESRD cases available…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA as a Biomarker of T Cell Mediated Rejection in Pediatric Kidney Transplant Patients

    R. Dandamudi1, S. Federman2, R. Woodward2, S. Dholakia2, L. Walther1, V. Dharnidharka1

    1Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, 2CareDx, Brisbane, CA

    *Purpose: T-cell-mediated rejection (TCMR) is a major cause of kidney allograft failure which requires kidney biopsy for a definitive diagnosis. Donor-derived cell-free DNA (dd-cfDNA) is…
  • 2022 American Transplant Congress

    Long-Term Outcomes of Crossmatch Positive Simultaneous Liver Kidney Transplants in the United States

    S. Riad1, E. Aby1, S. Jackson2, P. Nguyen3, N. Lim1, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Mhealth-Fairview, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: The long-term results of crossmatch positive (XM+) simultaneous liver-kidney (SLK) transplants are conflicting. We examined the association between crossmatch (XM) status and SLK outcomes…
  • 2022 American Transplant Congress

    Outcomes of a Standardized Antibody-Mediated Rejection (AMR) Treatment Protocol in Heart Transplant Recipients (HTR)

    J. Lee, T. Sam, J. Van Zyl, S. Mckean, L. Fuller, N. Wilson, A. Dao, R. Gottlieb, S. Hall, R. Patel

    Baylor University Medical Center, Dallas, TX

    *Purpose: AMR in HTR portends poor clinical outcomes. Reported mortality range between 20-50%, with higher rates reported for late AMR occurring at least 1 year…
  • 2022 American Transplant Congress

    Donor Derived Transmissions 2020: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC) with a Focus on COVID-19

    R. M. La Hoz1, A. Agarwal1, G. Berry1, K. Dunn1, J. Goldman1, S. Ho1, M. Kittleson1, D. H. Lee1, D. J. Levine1, C. Marboe1, G. Marklin1, S. Pouch1, R. Razonable1, S. Taimur1, H. Te1, A. Woolley1, C. Fox2, C. Jett2, S. Booker2, D. K. Klassen2, L. Danziger-Isakov1

    1OPTN DTAC, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: The OPTN DTAC, a multidisciplinary group, evaluates potential donor derived transmission events (PDDTE) to assess the likelihood of disease transmission.*Methods: Retrospective study of PDDTE…
  • 2022 American Transplant Congress

    Pd-1 Licenses Activated Treg for Lymphatic Migration

    W. Piao1, L. Li1, V. Saxena1, K. Hippen2, M. Shirkey1, B. Blazar2, I. Lape3, y. zhang3, J. Bromberg1

    1Surgery, University of Maryland, Baltimore, MD, 2University of Minnesota, Minneapolis, MN, 3Harvard Medical School, Boston, MA

    *Purpose: In addition to serving as fluid conduits, lymphatic vessels are critical portals for immune cell migration. Lymphatic endothelial cells (LECs) constitutively express high levels…
  • 2022 American Transplant Congress

    Type 1 Innate Lymphoid Cells Alleviate Acute Liver Injury Following Transplantation via Interferon-γ Mediated Pathway

    H. Kojima, K. Kadono, H. Hirao, K. J. Dery, J. Kupiec-Weglinski, Y. Zhai

    Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: Innate lymphoid cells (ILCs), a heterogeneous population of non-B non-T lymphocytes, have been found in recent years to plays key regulatory roles in tissue…
  • 2022 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorder in Kidney and Simultaneous Pancreas and Kidney Transplant Recipients Predictors, and Patient and Allograft Outcomes

    M. A. Mohamed1, E. A. Yousif1, V. Manchala2, F. Aziz3, N. Garg4, S. Parajuli4, D. Mandelbrot5, B. Astor1

    1Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2Medicine-Transplant Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 3University of Wsiconsin, Madison, WI, 4University of Wisconsin, Madison, WI, 5UW Health, Madison, WI

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a devastating complication following kidney and pancreas transplantation. 12% of UNOS waitlisted candidates had previous transplant and 20% are…
  • 2022 American Transplant Congress

    Molecular ABO Typing: An Effective Tool for Resolving Deceased Donor Indeterminate ABO Types

    D. Tanglao1, S. S. Musa1, J. J. Chew1, L. Santiago2, K. Herron3, B. O'Neale3, N. A. Lemp1, S. O. Dionne4

    1Eurofins DPT, Los Angeles, CA, 2Eurofins DPT, Centennial, CO, 3Eurofins DPT, Centennial, CA, 4Eurofins DPT, denver, CO

    *Purpose: In order to evaluate molecular ABO typing as an alternative method of blood typing that may be employed when indeterminate serological typing results are…
  • 2022 American Transplant Congress

    Impact of Pretransplant Infectious Diseases Wellness Visit on Vaccine Uptake in Solid Organ Transplant Candidates

    J. Jarrah, Z. Hanna, J. Williams, J. McCorquodale, T. Párraga, S. Greenlee, O. Abreu Lanfranco, M. Ramesh, R. del Busto, G. Alangaden

    Transplant Infectious Diseases, Henry Ford Hospital, Detroit, MI

    *Purpose: Vaccination rates in solid organ transplant candidates (SOTc) remains suboptimal. We report the effect of a dedicated Infectious Disease Pre-transplant (IDPT) clinic visit on…
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