2022 American Transplant Congress
The Feasibility of Changing HCC MELD Exception Criteria to an Exclusive DCD-Only Option: A Strategy to Increase DCD Utilization
Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: Outcomes of DCD liver transplantation is comparable to DBD but routine utilization of DCD liver grafts is surprisingly uneven in the US. A more…2022 American Transplant Congress
The High Incidence of Long-COVID-19 in Kidney Transplant Recipients: A Longitudinal Cohort Study
Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil
*Purpose: This study aimed to investigate the clinical consequences at 3 months after symptom onset among kidney transplant recipients surviving COVID-19.*Methods: This is an ongoing…2022 American Transplant Congress
Beyond CPRA: Identifying Sensitized Kidney Candidates with Markedly Low Access to Transplant
1UNOS, Richmond, VA, 2Hansa Biopharma AB, Lund, Sweden, 3Immucor, Norcross, GA
*Purpose: The Kidney Allocation System (KAS) improved the rates of transplantation in highly sensitized (HS) patients. However, a subset of HS patients remain at a…2022 American Transplant Congress
Natural vs Induced ABO Antibodies in a Murine Model: Role of Sex and T Cells
1University of Alberta, Edmonton, AB, Canada, 2University of Melbourne, Melbourne, Australia
*Purpose: Interaction of ‘natural’ ABO antibodies (nAbs) with their cognate AB(H)-antigens (Ags) poses a high risk of rapid rejection of ABO-incompatible (ABOi) organ transplants. We…2022 American Transplant Congress
Generation Of Insulin Producing Cells From Pancreatic Tissue With Long Standing Type 1 Diabetes
Imagine Pharma, Pittsburgh, PA
*Purpose: AIPCs (Activated Islet Proliferating Cells), are a novel cell population from isolated human islets obtained using a simple culture protocol that can generate cells…2022 American Transplant Congress
Belatacept Conversion in Proteinuric Kidney Transplant Recipients: Effects in a Prospective Trial and a Retrospective Cohort
*Purpose: Proteinuria after kidney transplantation is associated with worse allograft outcomes. B7-1 expression by podocytes has been linked to proteinuria by inducing podocyte migration which…2022 American Transplant Congress
Sex Disparities in Access to Liver Transplant for Waitlisted Patients with Meld 40
*Purpose: Women with end-stage liver disease are less likely than men to receive a liver transplant, due in part to MELD’s reliance on creatinine and…2022 American Transplant Congress
Role for Club Cell Secretory Protein in Inducing Exosomes and Activation of Immune Responses in Lung Transplanted Recipients for Cystic Fibrosis
*Purpose: Our lab has demonstrated that lower club cell secretory protein leads to immune responses to donor HLA and lung self-antigens (Collagen V, Kα1 Tubulin),…2022 American Transplant Congress
Pre-Transplant Frailty Predicts Infection After Liver Transplant in a Multi-Center Study of Older Adults
*Purpose: Frailty is a complex multi-system characterization of reduced physiologic reserve and functional decline in older adults. At the time of transplant, frailty has been…2022 American Transplant Congress
Hepatocyte SIRT1 Regulation of Apoptosis-Mediated Pyroptosis Cell Death in Mouse and Human Liver Transplantation
1UCLA Medical Center, Los Angeles, CA, 2NIEHS, Durham, NC
*Purpose: Cold static preservation is a gold-standard in orthotopic liver transplantation (OLT). However, the role of hepatocyte-specific SIRT1 transcriptional regulation of cell death programs during…
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