Am J Transplant, Volume 22, Suppl 3 Archives - Page 78 of 190 - ATC Abstracts

2022 American Transplant Congress
Digital Spatial Profiling of Kidney Allograft Biopsies with Chronic Allograft Dysfunction in African American Transplant Recipients
C. R. Dorr¹, S. A. Elmer¹, B. Wu², B. Guo², J. Czyzyk², G. Crary³, G. Onyeaghala¹, W. Oetting², P. Jacobson², R. B. Mannon⁴, G. Agarwal⁵, J. Maltzman⁶, A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴Medicine, University of Nebraska Medical Center, Omaha, NE, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Stanford University, Palo Alto, CA
*Purpose: Understanding tissue heterogeneity is important to identify the molecular and cellular mechanisms of kidney allograft loss in African American (AA) transplant recipients. Our aim…
2022 American Transplant Congress
Higher Baseline Serum Creatinine Levels AreAssociated with an Increased Incidence of Renal Replacement Therapy in Patients with Hepatorenal Syndrome Type 1 on the Liver Transplant Waitlist
S. N. Sclair¹, A. Befeler², K. Jamil³
¹Hepatology, University Hospitals Cleveland Medical Center & Case Western Reserve University, Cleveland, OH, ²Gastroenterology, Hepatology, Transplant Hepatology, Saint Louis University School of Medicine, St Louis, MO, ³Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ
*Purpose: Pretransplant and posttransplant renal replacement therapy (RRT) is associated with increased morbidity and mortality in liver transplant recipients, including those with Hepatorenal syndrome type…
2022 American Transplant Congress
Pregnancy After Heart Transplant Does Not Negatively Impact Long Term Patient Survival
M. J. Moritz¹, D. Lee², C. Madu², S. Hossain³, L. A. Coscia⁴, S. Rao⁵, S. Constantinescu⁶
¹Surgery, Lehigh Valley Health Network, Allentown, PA, ²Cardiovascular Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL, ³Data Analytics, University of South Florida, Muma College of Business, Tampa, FL, ⁴Transplant Pregnancy Registry International, Philadelphia, PA, ⁵Nephrology, University of Virginia Health System, Charlottesville, VA, ⁶Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA
*Purpose: To evaluate the impact of pregnancy on patient survival in heart transplant recipients (HTRs), we linked the Transplant Pregnancy Registry International (TPRI) dataset with…
2022 American Transplant Congress
Higher Immunogenicity of a Third Heterologous Dose with BNT262b2 Mensanger RNA Vaccine Compared to a Homologous Dose in Kidney Transplant Recipients Fully Vaccinated with Inactivated Whole-Virion CoronaVac Vaccine
L. V. Pouzo¹, M. Nakamura¹, L. A. Viana², E. Lucena¹, M. Jesus¹, G. Bittencourt Pereira Lima¹, J. Medina¹, H. Tedesco¹, M. Cristelli¹
¹Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil, ²Nephrology, Hospital do rim, Sao Paulo, Brazil
*Purpose: This study aims to compare the immunogenicity of a third dose of the heterologous BNT262b2 mRNA vaccine versus the homologous inactivated whole-virion CoronaVac vaccine…
2022 American Transplant Congress
Autologous Mesenchymal Stem Cells for Treatment of Chronic Antibody-Mediated Kidney Graft Rejection: Report of the First Phase I/II Clinical Case Series
Ž. Večerić-Haler¹, M. Sever², N. Kojc³, G. Mlinšek¹, M. Oblak¹, P. Halloran⁴, A. Aleš Rigler¹, J. Buturović Ponikvar¹, M. Arnol⁵
¹Nephrology, UMC Ljubljans, Ljubljana, Slovenia, ²Haematology, UMC Ljubljans, Ljubljana, Slovenia, ³Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana,, Ljubljana, Slovenia, ⁴Division of Nephrology and Transplant Immunology, University of Alberta, Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ⁵University Medical Centre Ljubljana, Ljubljana, Slovenia
*Purpose: The aim of this study is to evaluate the safety and efficacy of autologous mesenchymal stem cellc (MSCs) in combination with standard of care…
2022 American Transplant Congress
Successful Transplantation of CPRA 95-100% HLA Incompatible (HLA I) KPD Candidates: A New Combined KPD Matching Strategy at a Single Centre
H. Helwani¹, D. Broering², I. Alahmadi³, T. Ali¹, F. Alzayer⁴, M. Mankowski⁵, A. Algharabli¹
¹Kidney & Pancreas Health Centre, OTCoE, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ²Organ Transplant Centre of Excellence, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ³Kidney & Pancreas Transplant Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ⁴King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ⁵King Abdullah University for Science & Technology, Saudi Arabia, Saudi Arabia
*Purpose: The six components of the new strategy are Universal flexible assignments of unacceptable antigens (UA); individualized deletion of carefully selected UA; inclusion of compatible…
2022 American Transplant Congress
Preoperative Antibiotics Administration is Important to Prevent Hand Port-Site Infection After Hand-Assisted Laparoscopic Donor Nephrectomy for Living-Donor Kidney Transplantation
T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, N. Goto, T. Ichimori, S. Narumi, Y. Watarai
Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan
*Purpose: Due to the profound organ shortage, the number of living donor kidney transplantation (LDKT) is increasing. Hand-assisted laparoscopic donor nephrectomy (HALDN) is widely performed…
2022 American Transplant Congress
Increasing Proportion of High-Risk Cytomegalovirus (CMV) Donor Positive/recipient Negative (D+R-) Serostatus in Solid Organ Transplant Recipients (SOTRs)
H. Imlay¹, M. M. Wagener², N. Singh², A. P. Limaye³
¹University of Utah, Salt Lake City, UT, ²University of Pittsburgh, Pittsburgh, PA, ³University of Washington, Seattle, WA
*Purpose: CMV D+R- serostatus is independently associated with worse long-term graft and patient survival across many organ transplant types despite current prevention and treatment strategies.…
2022 American Transplant Congress
Deletion of Fibroblastic Reticular Cell Derived Laminin A4 Impairs Lymph Node Vasculature and Conduits
L. Li¹, M. Shirkey¹, W. Piao¹, A. Kensiski¹, V. Saxena¹, T. Zhang¹, X. Li², J. Zhao², S. Gavzy¹, R. Abdi², J. Bromberg¹
¹UMB, Baltimore, MD, ²Harvard University, Boston, MA
*Purpose: Fibroblastic reticular cells (FRCs) support lymph node (LN) structure by producing various functional extracellular matrix (ECM) components. We hypothesized that FRCs and their ECM…
2022 American Transplant Congress
Status Exception Use in the New Seven-Tiered Heart Allocation System
A. Plana¹, A. Kanelidis¹, W. F. Parker², V. Jeevanandam³, C. Salerno³, B. Smith¹, S. Kalantari¹, S. Pinney¹, J. Grinstein¹
¹Cardiology, University of Chicago, Chicago, IL, ²Pulmonary/Critical Care, University of Chicago, Chicago, IL, ³Cardiac Surgery, University of Chicago, Chicago, IL
*Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…