2022 American Transplant Congress
Creating a Workflow for the Electronic Medical Record Allows Living Donor Liver Transplantation Programs to Track Candidates and Identify Areas for Optimization
1Yale University School of Medicine, New Haven, CT, 2Yale New Haven Hospital, New Haven, CT
*Purpose: To provide a pathway to increase living donor liver transplantation (LDLT) opportunities through creation of a simple workflow algorithm embedded within the EPIC electronic…2022 American Transplant Congress
Comparison of Immediate-Release Tacrolimus to Envarsus XR on the Development of Donor Specific Antibodies in Kidney Transplant Recipients
Northwestern Memorial Hospital, Chicago, IL
*Purpose: Major causes of de novo development of donor specific antibodies (DSA) after kidney transplant include medication noncompliance and immunosuppression minimization or elimination that may…2022 American Transplant Congress
Belatacept-Based Maintenance Immunosuppression Promoted Long-Term Antibody-Mediated Rejection Free Graft Survival After Desensitization in Sensitized Multiparous Female Recipients
Duke Transplant Center, Durham, NC
*Purpose: Amongst sensitized patients awaiting a transplant, females are disproportionately represented. To date, nonhuman primate (NHP) models of transplantation have relied on male animals, sensitized…2022 American Transplant Congress
Optimization of Human Liver Organoid Model for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
*Purpose: The aim of our project is to develop an in vitro 3D human liver organoid (3D-HLO) model for studying nonalcoholic fatty liver disease (NAFLD)…2022 American Transplant Congress
Is a Single Dose of Steroids in Adult Living Donor Liver Transplant Safe? – A Cohort Analysis
University of California San Francisco, San Francisco, CA
*Purpose: Steroids increase morbidity, and steroid avoidance (SA) has been studied in deceased donor liver transplant but, little is known about SA in living donor…2022 American Transplant Congress
Knowledge Gaps and Perceptions of Liver Disease and Liver Transplant Referral Serve as Barriers to Transplant Among Primary Care Providers in Non-Urban America
*Purpose: The path to liver transplant (LTX) typically begins with primary care providers(PCPs), and is dependent on timely referral to transplant centers. The referral patterns…2022 American Transplant Congress
Recipient and Center Factors Associated with Immunosuppression Practice Beyond the First Year After Liver Transplantation
1University of Pennsylvania, Philadelphia, PA, 2University of Miami, Miami, FL
*Purpose: To investigate patient and center factors associated with differences in immunosuppression management in the first 5 years after LT.*Methods: A retrospective cohort of 11,326…2022 American Transplant Congress
Evaluation of Compliance and Efficacy with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Tacrolimus in Kidney Transplant Recipients
*Purpose: The purpose of this study is to evaluate compliance and efficacy of The Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype guided tacrolimus…2022 American Transplant Congress
Simultaneous Liver/ Kidney Transplant Reduces Both Donor Specific and Non-Donor Specific HLA Antibodies
Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Kidney allografts can be transplanted across strong donor specific antibody (DSA) barriers in simultaneous liver/kidney transplant (SLK) recipients. It is suggested that preformed DSAs…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…
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