ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA and Gene Expression Profiling for Surveillance of Renal Allograft Injury and Rejection

    A. N. Carrier, A. Crane, M. Pinedo, A. Bartosic, A. Haririan, J. R. Scalea, M. R. Weir, J. S. Bromberg

    University of Maryland, Baltimore, MD

    *Purpose: Donor derived cell free DNA (dd-cfDNA) and gene expression profiling offer non-invasive methods of early detection of graft injury and rejection in solid organ…
  • 2022 American Transplant Congress

    Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data

    A. E. Mangus1, C. Kubal2, B. Ekser3, P. Mihaylov4, A. J. Lutz1, J. Fridell5, R. Mangus6

    1Indiana University Purdue University of Indianapolis, Indianapolis, IN, 2Indiana University Hospital, Indianapolis, IN, 3Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 4Indiana Univ School of Medicine, Indianapolis, IN, 5Indiana University School of Medicine, Indianapolis, IN, 6Indiana University, Indianapolis, IN

    *Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
  • 2022 American Transplant Congress

    Normothermic Organ Preservation: The New Standard?

    K. Mistry

    Sanford Health, Fargo, ND

    *Purpose: Normothermic perfusion (NMP) is a new technique that has been introduced into transplantation expanding capacity for organ utilization. NMP has been shown to be…
  • 2022 American Transplant Congress

    Intraabdominal Hypertension in the Death by Neurologic Criteria Organ Donor

    C. Schardein1, M. Moncure2, S. Craft1, S. Sanders3

    1General Surgery, University of Missouri at Kansas City, Kansas City, MO, 2Trauma and Critical Care Surgery, University of Missouri at Kansas City, Kansas City, MO, 3MTN, Kansas City, MO

    *Purpose: This study attempts to identify the incidence of abdominal compartment syndrome (ACS) within the death by neurological criteria organ donor population, provide timely intervention,…
  • 2022 American Transplant Congress

    Normal Saline vs Electrolyte-a Use Peri- and Post-Operatively in Adult Kidney Transplant Recipients

    K. R. Szempruch, A. D. Martschenko, H. Arora, R. Isaak, R. Prasad, P. Serrano

    UNC Medical Center, Chapel Hill, NC

    *Purpose: 0.9% normal saline (NS) has been used as the standard fluid replacement in kidney transplant recipients (KTRs) to prevent dehydration and to improve renal…
  • 2022 American Transplant Congress

    A Novel Prospective Validation Trial Of Multiple Blood-based RNA Signature Assays Pre And Post Kidney Transplant To Predict Rejection

    L. Gallon1, P. O'Connell2, A. Chang3, M. Donovan4

    1Northwestern Univ, Chicago, IL, 2Westmead Inst, Sydney, Australia, 3Univ of Chicago, Chicago, IL, 4Verici Dx, Franklin, TN

    *Purpose: The accuracy and utility of clinically defined and analytically validated predictive biomarkers in kidney transplantation is limited. We leveraged prior feasibility blood-RNA studies to…
  • 2022 American Transplant Congress

    Early vs. Late Heparin Administration After Declaration of Death in DCD Donors Does Not Impact Short Term Outcomes in Kidney Transplantation

    A. M. Hawxby, R. Ketcham, R. Squires, J. P. Orlowski, H. Solomon, C. Hostetler

    Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK

    *Purpose: Kidneys from Donation after Cardiac Death (DCD) donors are well-known to have satisfactory outcomes post-transplant. In DCD donors, heparin is typically given immediately prior…
  • 2022 American Transplant Congress

    Thymoglobulin Induction Protocol: Quality Improvement Project via Clinical Audit

    S. Mouawad1, J. Dann1, A. Kumar2, S. Rao3

    1University of Virginia Health System, Charlottesville, VA, 2Nephrology, University of Virginia, Charlottesville, VA, 3University of Virginia, Charlottesville, VA

    *Purpose: The aim of our study was to analyze the adequacy of the thymoglobulin (rATG) induction protocol for the expanding and higher complexity kidney transplant…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA Testing in Kidney Transplantation: Do One-Month Values Have Any Prognostic Significance?

    B. K. Sharda1, M. Garner1, A. Farney1, G. Orlando2, J. Rogers2, C. Jay3, A. Daniel1, A. Guiterrez1, N. Sakhovskaya1, R. Stratta1

    1ATRIUM HEALTH Wake Forest Baptist Medical Center, Winston Salem, NC, 2Wake Forest Baptist Medical Center, Winston Salem, NC, 3Wake Forest Baptist Health, Winston-Salem, NC

    *Purpose: Plasma-based donor-derived cell-free DNA (dd-cfDNA) assays have been proposed as an alternative to percutaneous renal allograft biopsy which is the current gold standard for…
  • 2022 American Transplant Congress

    Towards Bionic Organs: Biocompatibility Of Newly Developed Porcine Decm-based Hydrogels.

    M. Rachalewski, M. Klak, D. Ujazdowska, P. Cywoniuk, T. Dobrzanski, G. Tymicki, K. Kosowska, T. Bryniarski, A. Berman, M. Wszola

    Foundation of Research and Science Development, Warsaw, Poland

    *Purpose: There is a growing interest in fabrication of bioinks which on one hand biocompatible and on the other hand possess mechanical properties which would…
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