Am J Transplant, Volume 22, Suppl 3 Archives - Page 72 of 190 - ATC Abstracts

2022 American Transplant Congress
Concordance of POLQ and PARP-1 Expression and MMEJ Type Viral Integration in the Progression of BKPyV-Associated Diseases
Y. Wang¹, Z. Yan¹, Y. Liu², J. Geng³, W. Deng¹, R. Xia¹, W. Zeng¹, J. Xu¹, C. Wu⁴, Y. Miao¹
¹Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China, ²Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, ³Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China, ⁴Departments of Urology & Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
*Purpose: To reveal the mechanism of the increasing dominant position of integration, especially the microhomology-mediated end joint (MMEJ) form in the development of BK Polyomavirus…
2022 American Transplant Congress
Pretransplant Rifaximin Treatment Improves Liver Transplant Outcomes in Mice and Humans
H. Kojima, S. Kageyama, T. Ito, D. Noguchi, H. Hirao, K. Kadono, K. J. Dery, F. Kaldas, J. Kupiec-Weglinski
UCLA Medical Center, Los Angeles, CA
*Purpose: We recently reported modifications of the gut microbiota by amoxicillin influences liver allograft function. Rifaximin (RFX), a nonabsorbable oral antimicrobial agent with a low…
2022 American Transplant Congress
Multiomic Analyses Of Two Pig Kidney To Human Xenotransplants
B. Keating¹, B. Piening², M. Mangiola³, J. Stern⁴, W. Zhang⁵, A. Griesemer⁶, B. Lonze⁷, M. Snyder⁸, J. Boeke⁵, R. Montgomery⁷
¹University of Pennsylvania, Philadelphia, PA, ²Providence Cancer Center, Portland, OR, ³New York University Langone Medical Center, New York, NY, ⁴Department of Surgery, NYU Langone, New York, NY, ⁵Institute of Systems Genetics, NYU Langone, New York, NY, ⁶Surgery, NYU Langone, New York, NY, ⁷NYU Langone Transplant Institute, New York, NY, ⁸Genetics, Stanford, Palo Alto, CA
*Purpose: Organ shortage remains a major limitation within transplantation, with waiting lists greatly outpacing the number of donors available. Pig organs offer significant advantages for…
2022 American Transplant Congress
Impact of Recipient Warm Ischemic Time on Outcomes Associated with High KDPI and DCD Donor Kidneys: Cold Ischemic Time Remains Paramount
M. L. Jacobs, R. Stratta, M. Garner, B. Sharda, A. Farney, G. Orlando, A. Reeves-Daniel, C. Jay
Department of Surgery, Atrium Health Wake Forest Baptist, Winston Salem, NC
*Purpose: Previously we demonstrated that cold ischemic time (CIT) beyond 24 hours was an important risk predictor of early graft loss (EGL) and primary non-function…
2022 American Transplant Congress
Use of New 2021 CKD-EPI as an Endpoint in Transplant Trials May Significantly Influence Observations
E. Yanqui¹, H. Hames¹, T. Shi², A. R. Shields¹, E. S. Woodle¹, R. R. Alloway¹
¹University of Cincinnati, Cincinnati, OH, ²CCHMC, Cincinnati, OH
*Purpose: GFR equations have recently been modified primarily to avoid disadvantaging black populations. The purpose of this study was to evaluate renal function and the…
2022 American Transplant Congress
Identifying Predictors of Pediatric Heart Only versus Combined Heart-Liver Transplantation
K. Zhang, S. Chen, A. Syed, A. Gallo, C. Esquivel, C. Bonham, S. Hollander, M. Ma, J. Han, N. Ebel
Stanford University, Stanford, CA
*Purpose: A standardized protocol to identify which patients with Fontan failure require combined heart liver transplant (cHLT) versus isolated heart transplant (HT) has not yet…
2022 American Transplant Congress
The Outcome of Clostridioides Difficile Infection in Hospitalized Intestinal Transplant Recipients
W. Amjad¹, T. Schiano², A. Malik³, M. Segovia⁴, S. Jafri⁵
¹Clinical Investigation, Harvard Medical School, Boston, MA, ²Intestinal and Liver Transplantation, Mount Sinai Medical Center, New York, NY, ³Internal Medicine, Saint Joseph's Medical Center, Stockton, CA, ⁴Small Intestine and Liver Transplant, Duke University School of Medicine, Durham, NC, ⁵Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI
*Purpose: Organ transplantation is a known risk factor of Clostridioides difficile infection. There is limited published data on the frequency and impact of CDI in…
2022 American Transplant Congress
A Single Center Retrospective Cohort Study Comparing the Rates of MDROs in DCD vs DBD Liver Transplant Recipients
J. Walker, C. Bennett, R. Griffin, B. Orandi, J. Locke, R. Cannon, S. Sheikh, A. Nellore, R. Lee
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Donation after cardiac death (DCD) offers an opportunity to reduce wait list mortality with similar 5-year graft survival rates to donation after brain death…
2022 American Transplant Congress
M1 Macrophage Polarization in Antibody-Mediated Rejection After Renal Transplantation and the Intervention Study of Iguratimod
M. Zheng¹, W. Zijie², Z. Gui³, R. Tan¹, M. Gu³
¹Department of Urology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China, ²Jiangsu Province Hospital, Nanjing, China, ³Department of Urology, The Second Affiliated Hospital with Nanjing Medical University, Nanjing, China
*Purpose: After kidney transplantation, Antibody Mediated Rejection (ABMR) is the main factor affecting the long-term survival of kidney transplantation. Previous studies have confirmed that macrophage…
2022 American Transplant Congress
Efficacy and Safety of a Delayed Graft Function Protocol in Kidney Transplant Recipients
V. Vu¹, S. Bhayana², H. Sweiss¹, N. Castro¹, R. Hall¹, J. Nelson¹
¹University Health, San Antonio, TX, ²University of Texas Health Science Center at San Antonio, San Antonio, TX
*Purpose: To evaluate the efficacy and safety of a protocol increasing the net state of immunosuppression for adult kidney transplant recipients (KTR) with delayed graft…