ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Tacrolimus and Mycophenolic Acid Therapeutic Exposure Targets in Black and White Kidney Transplant Recipients

    K. Tornatore1, K. Attwood1, S. Chang1, A. Gundroo2, B. Murray1

    1Univeristy at Buffalo/SUNY, Buffalo, NY, 2Ohio State Medical Center, Columbus, OH

    *Purpose: Tacrolimus and Mycophenolic Acid(MPA), the preferred immunosuppressive regimen for kidney transplant recipients(KTR), exhibit interpatient pharmacokinetic variability which may impact allograft survival in Black and…
  • 2022 American Transplant Congress

    Longitudinal Characterization of the Microvirome in a Cohort of Renal Transplant Recipients

    A. C. Johnson, G. Karadkhele, C. P. Larsen

    Emory University, Atlanta, GA

    *Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections, with different immunosuppression regimens resulting in…
  • 2022 American Transplant Congress

    Urinary Cell CTOT-04 Signature is Diagnostic of Glomerulitis in Kidney Allograft Biopsies

    T. Salinas1, C. Li1, C. Snopkowski1, K. Chen1, S. Albakry1, S. Salvatore2, S. Seshan2, J. R. Lee1, M. Thangamani1, D. Dadhania1, M. Suthanthiran1

    1Nephrology, Weill Cornell-NYPH, New York, NY, 2Pathology, Weill Cornell-NYPH, New York, NY

    *Purpose: Antibody mediated rejection is a significant complication after kidney transplantation and is an important cause of allograft failure. In the multicenter CTOT-04 study, we…
  • 2022 American Transplant Congress

    TNX-1500, an Fc-Modified Anti-cd154 Antibody, Prolongs Nonhuman Primate Cardiac Allograft Survival

    S. Miura1, Z. Abady1, F. Pollok1, M. Ma1, K. Kinoshita1, S. Fogarty2, P. Maguire2, B. Daugherty2, S. Lederman2, R. Pierson III1

    1Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA, 2Tonix Pharmaceuticals, Chatham, NJ

    *Purpose: Blockade of the CD40/CD154 T cell costimulation pathway is a promising approach to replace current clinical immunosuppression. TNX-1500 (TNX) is a novel humanized anti-CD154…
  • 2022 American Transplant Congress

    Twelve Month Outcomes of Kidney Transplantation from Hepatitis C Viremic Deceased Donors to Aviremic Recipients

    L. A. Binari, R. C. Forbes, S. Rega, I. D. Feurer, A. Dreher, S. Shawar, H. Schaefer, D. Shaffer, B. P. Concepcion

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: The utilization of Hepatitis C viremic (HCV+) deceased donor kidneys for uninfected recipients allows for increased opportunities for organ transplantation. Initial studies have indicated…
  • 2022 American Transplant Congress

    Expanding Access to Robotic Kidney Transplantation for Candidates with High BMI. A Training Tool for Transplant Centers

    J. A. Almario Alvarez, G. Aguiluz, V. Valle, R. Bustos, S. Akshelyan, A. M. Fratti, P. D. Cocco, M. Spaggiari, I. G. Tzvetanov, E. Benedetti

    Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: Recently published literature has demonstrated favorable outcomes for Robotic Kidney Transplant (RKT) in high BMI recipients. The University of Illinois at Chicago (UIC) has…
  • 2022 American Transplant Congress

    Gender Disparities in Kidney Transplantation Referral Vary by Age and Race in the Southeast US

    L. Smothers1, R. Patzer1, S. Pastan1, D. DuBay2, J. Harding1

    1Emory University, Atlanta, GA, 2Medical University of South Carolina, Charleston, SC

    *Purpose: Men (vs. women) are more likely to be waitlisted or receive a kidney transplant. Whether gender disparities exist in earlier transplant steps (i.e., referral)…
  • 2022 American Transplant Congress

    Financial Barriers Experienced During the Transplant Process by Caregivers of Children with End Stage Kidney Disease

    R. Goldfarb Terry1, A. Edwards1, U. Parlin2, A. Chung1, S. Amaral1

    1Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Known socioeconomic disparities in transplant referral and evaluation exist in adults with end-stage kidney disease, but little is known about the financial burden that…
  • 2022 American Transplant Congress

    Finding Living Donors on Social Media for Pediatric Kidney and Liver Transplant Candidates

    D. Yoeli1, S. Mathai2, J. Kaar3, C. Mata3, A. Feldman4, M. Bock5, W. Jackson6, M. Adams1

    1Surgery, University of Colorado Anschutz Medical, Aurora, CO, 2School of Medicine, University of Colorado Anschutz Medical, Aurora, CO, 3Center for Research in Outcomes for Children's Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, 4Section of Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, Children's Hospital Colorado, Aurora, CO, 5Department of Pediatric Nephrology, Children's Hospital Colorado, Aurora, CO, 6Hepatology, University of Colorado Anschutz Medical Campus, Aurora, CO

    *Purpose: Living donor kidney and liver transplantation are associated with superior outcomes in children. We hypothesized that social media can be a valuable tool to…
  • 2022 American Transplant Congress

    Factors Associated with Ineligible Donor Use in the United States

    L. DeRoos, B. Li, M. Lavieri, D. Hutton, N. Parikh

    University of Michigan, Ann Arbor, MI

    *Purpose: Increasing and standardizing the use of donors who do not meet the OPTN-defined eligibility criteria would increase the number of organs available for transplantation…
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