ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Trajectory Analysis Of Single Cell RNAseq Data Suggest Intrarenal Induction Of Tregs In Spontaneously Accepted Kidney Allografts

    M. Guinn1, E. S. Szuter1, T. Yokose1, J. Ge2, B. Kwon1, I. Rosales3, P. S. Russell1, A. Cuenca2, J. Madsen1, R. Colvin3, A. Alessandrini1

    1Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Boston Children's Hospital, Boston, MA, 3Department of Pathology, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    *Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) are spontaneously accepted independent of the recipient’s thymus, spleen, and lymph nodes.…
  • 2022 American Transplant Congress

    Renal Function at Five Years from a Randomized Multicenter Trial of Belatacept-Based CNI Free and Early Steroid Withdrawal Immunosuppression

    E. Yanqui1, H. Hames1, A. R. Shields1, T. Shi1, A. L. Christianson1, J. Kremer2, A. Govil1, R. R. Alloway1, E. S. Woodle1

    1University of Cincinnati, Cincinnati, OH, 2Christ Hospital, Cincinnati, OH

    *Purpose: BENEFIT and BENEFIT EXT trials have demonstrated that belatacept-based immunosuppression was associated with improved long term renal allograft function compared to cyclosporine-based immunosuppression. Similar…
  • 2022 American Transplant Congress

    Quantification of Center Aggressiveness in Accepting Sub-Optimal Kidney Donations from Deceased Donors in the US

    T. P. Chiang1, M. Eagleson1, A. Massie1, M. Krach1, D. Segev1, J. Garonzik Wang2

    1Department of Surgery, Johns Hopkins University, Baltimore, MD, 2School of Medicine and Public Health, University of Wisconsin, Madison, WI

    *Purpose: Understanding center-level differences in usage of marginal deceased-donor kidneys (suboptimal kidneys, SOK) can help centers increase their deceased-donor transplant rate (DDKT), and to direct…
  • 2022 American Transplant Congress

    Variation in Immunosuppressive Regimen in Children Receiving Liver Transplants: An Analysis of the UNOS Database

    V. K. Raghu1, J. E. Squires1, C. Confair2, E. Katz-Eisenberg2, G. V. Mazariegos3, E. R. Perito4

    1Pediatrics, University of Pittsburgh, Pittsburgh, PA, 2Starzl Network for Excellence in Pediatric Transplantation, Pittsburgh, PA, 3UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 4Pediatrics, University of California San Francisco, San Francisco, CA

    *Purpose: Optimizing immunosuppression (IS) was identified as a priority for pediatric liver transplant (LT) families and providers in the Starzl Network, a multi-center learning health…
  • 2022 American Transplant Congress

    Surveillance with Protocol Biopsies for Rejection Significantly Impacts Survival Following Intestine Transplant

    J. R. Sherwood1, Y. Ichkhanian2, N. Beltran3, S. Nagai3, S. Jafri4

    1Wayne State School of Medicine, Detroit, MI, 2Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, 3Department of Transplant Surgery, Henry Ford Hospital, Detroit, MI, 4Division of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI

    *Purpose: Frequent surveillance biopsy is required on the first month post intestinal transplant(IT) due to high-risk of acute rejection. However, the utility and the frequency…
  • 2022 American Transplant Congress

    Novel Portable Hypothermic Cardiac Preservation Device Enhances Cardiac Viability and Function of the Isolated Porcine Hearts

    K. Andrijauskaite, R. J. Veraza, R. P. Lopez, E. C. Cisneros, I. J. Jessop, M. D. Watt, L. Bunegin

    Vascular Perfusion Solutions, Inc, San Antonio, TX

    *Purpose: Cardiac heart transplantation is the gold standard for treating end-stage heart failure; however, the list of patients waiting for heart transplants continues to increase.…
  • 2022 American Transplant Congress

    Characterization of Kidney Allograft Pathology Using the Histomap Gene Expression Profile (GEP) and Formalin Fixed Paraffin Embedded (FFPE) Tissue

    N. Garg1, K. Degner2, H. Zhang3, W. Tian3, F. Aziz4, S. Parajuli2, W. Zhong2, N. Wilson2, S. Panzer1, A. Djamali2

    1University of Wisconsin Madison, Madison, WI, 2University of Wisconsin, Madison, WI, 3CareDx, Brisbane, CA, 4University of Wsiconsin, Madison, WI

    *Purpose: The new Banff Human Organ Transplant (B-HOT) gene panel assessed on nCounter system has been created through a collaboration between NanoString and the Banff…
  • 2022 American Transplant Congress

    Chronic Active Antibody Mediated Rejection: 3 Month Response Rates to Treatment and Predictors of Graft Survival

    F. Aziz, M. Jorgenson, S. Parajuli, N. Garg, V. Manchala, E. Yousif, D. Mandelbrot, L. Hidalgo, M. Mohamed, W. Zhong, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: There is limited information on effectiveness of treatment and predictors of graft survival following chronic active antibody mediated rejection (cABMR) in kidney transplant recipients…
  • 2022 American Transplant Congress

    Implementing Genetic Testing in the Evaluation of the Kidney Transplant Candidate

    F. Abu Al Rub1, Y. Caliskan2, H. Randall2, B. Bastani2, V. Fleetwood3, M. Nazzal2, C. Varma2, K. Lentine2

    1St. Louis University, St Louis, MO, 2St. Louis University, St. Louis, MO, 3Department of Transplantation, St. Louis University, St. Louis, MO

    *Purpose: To describe the incorporation of a genetic renal panel to improve the characterization of end stage kidney disease (ESKD) etiology in the kidney transplant…
  • 2022 American Transplant Congress

    Measurement of Physical Activity and Frailty in the Early Post-Operative Period After Kidney Transplant-Single-Center Prospective Pilot Study Using Fitbit Watch

    T. Shamaa, L. Allenspach, O. Shamaa, S. Shimada, C. Crombez, O. Hage-Hassan, T. Kitajima, S. Yeddula, I. Bajjoka, L. Malinzak, J. Denny, D. Kim, M. Abouljoud, S. Nagai

    Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Physical activity monitors (PAMs) allow patients to track multiple health parameters. PAM’s may be helpful to assess a patient’s physical recovery after a Kidney…
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