2022 American Transplant Congress
Identification of Akkermansia Muciniphila and Bacteroides Thetaiotaomicron Associated with the Alleviation of Peritransplant Liver Damage in Mouse Recipients
*Purpose: Although recent evidence shows that modifications of gut microbiota by antibiotics (Abx) influences liver allograft function, its compositional role in orthotopic liver transplantation (OLT)…2022 American Transplant Congress
Fixed-Dose Rituximab for Pre-Transplant DSA in Kidney Transplant Recipients
*Purpose: Donor specific antibodies (DSAs) occur in 15-30% of kidney transplant recipients (KTRs) and are associated with rejection and graft loss. Rituximab (RTX), an antiCD20…2022 American Transplant Congress
Exosomal TGFbeta:LAP as Immunosuppressive Mediator of Allo-Tolerance
*Purpose: TGFβ has long been known as a key component in tolerance mediated by Treg cells. Here we show that, unlike IL10, but like CD39/CD73,…2022 American Transplant Congress
Characterization of GZMB+ Bregs Transcriptome and Their Impact on Target Cells in Single-Cell RNA-seq
CRTI- INSERM UMR 1064, Nantes, France
*Purpose: During the inflammatory process, the immune system capacity to regulate itself is mandatory to balance effector positive feedback, avoid allergies and autoimmunity. Different subsets…2022 American Transplant Congress
Impact of the Weekend Effect on Adult and Pediatric Liver or Kidney Offer Acceptance
Transplant Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA
*Purpose: Weekends may impose resource and manpower constraints on hospitals. Studies using data from prior allocation schemas showed increased adult organ discards on weekends. We…2022 American Transplant Congress
dd-cfDNA Varies Among Diagnostics Groups of Pulmonary AMR
*Purpose: Antibody mediated rejection (AMR) in lung transplant remains complex, with differential diagnosis often overlapping with other causes of lung dysfunction. Diagnostic certainty declines to…2022 American Transplant Congress
Pooled Prevalence of Pulmonary Embolism in Lung Transplant Recipients – A Meta-Analysis
Department of Pulmonary and Critical Care, Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Similar to other operations, lung transplantation surgery has been associated with an increased risk of venous thromboembolism. While various studies have aimed to estimate…2022 American Transplant Congress
Normothermic Machine Perfusion of the Liver Supports Protein Translation and Mitochondrial Function While Reducing Protein Degradation and Metabolic Imbalance: A Proteomics Study
*Purpose: Liver preservation by normothermic machine perfusion (NMP) involves perfusion of the graft with oxygenated blood and nutrients. The NMP Liver trial by the Consortium…2022 American Transplant Congress
Multicenter Effort Assessing the Effects of COVID Infection and Vaccination on HLA Antibodies in Waitlisted Patients with ESRD
*Purpose: Although rare, infection and vaccination have been reported to result in human leukocyte antibodies (HLA). We analyzed the effect of SARS-CoV2 infection, or COVID-19…2022 American Transplant Congress
Portal Vein Thrombosis and DCD Liver Transplantation: Dangerous Combination or Clinical Opportunity?
*Purpose: Individually, recipient portal vein thrombosis (PVT) and donation after circulatory death (DCD) allografts are associated with a higher risk of poor deceased donor liver…
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