ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Correlation of Non-HLA Antibodies and Biopsy-Proven Antibody-Mediated Rejection

    N. Patel, M. Kittleson, J. Patel, T. Singer-Englar, S. Kim, D. Chang, E. Kransdorf, D. Megna, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Non-HLA antibodies are seen in heart transplantation (HTx), but the clinical significance has not been established. In many cases, non-HLA antibodies are drawn, but…
  • 2022 American Transplant Congress

    Concordance of POLQ and PARP-1 Expression and MMEJ Type Viral Integration in the Progression of BKPyV-Associated Diseases

    Y. Wang1, Z. Yan1, Y. Liu2, J. Geng3, W. Deng1, R. Xia1, W. Zeng1, J. Xu1, C. Wu4, Y. Miao1

    1Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, 3Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China, 4Departments of Urology & Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    *Purpose: To reveal the mechanism of the increasing dominant position of integration, especially the microhomology-mediated end joint (MMEJ) form in the development of BK Polyomavirus…
  • 2022 American Transplant Congress

    Pretransplant Rifaximin Treatment Improves Liver Transplant Outcomes in Mice and Humans

    H. Kojima, S. Kageyama, T. Ito, D. Noguchi, H. Hirao, K. Kadono, K. J. Dery, F. Kaldas, J. Kupiec-Weglinski

    UCLA Medical Center, Los Angeles, CA

    *Purpose: We recently reported modifications of the gut microbiota by amoxicillin influences liver allograft function. Rifaximin (RFX), a nonabsorbable oral antimicrobial agent with a low…
  • 2022 American Transplant Congress

    Effects of Race, Previous CoV2 Exposure and the Length and Type of Maintenance Immunosuppression on Protective Immunity to COVID19 Vaccine in Solid Organ Transplant Recipients

    A. Choudhary1, M. Lerman2, S. Khan2, J. Hunt2, A. Nikaein3, D. Calianese1, E. Kalu2, D. K. Jaijyan4, W. Honnen1, A. Pinter1

    1PHRI, Rutgers University, Newark, NJ, 2Transplant, Medical City Dallas, Dallas, TX, 3Texas Speciality, Medical City Dallas, Dallas, TX, 4pHRI, Rutgers University, Newark, NJ

    *Purpose: The diverse factors affecting the vaccine induced neutralizing antibody response in solid organ transplant recipients and their immunity against CoV2 variants are needed to…
  • 2022 American Transplant Congress

    Does Donor-to-Recipient Weight Mismatch Influence Short Term Outcomes of Deceased Donor Kidney Transplantation?

    L. Sabbagh, M. Killackey, H. Jeon, K. Atiemo, A. Paramesh, A. Vijay

    Tulane University School of Medicine, New Orleans, LA

    *Purpose: The functional nephron mass of an allograft is often taken into consideration when contemplating transplanting a small kidney into a large recipient. We aim…
  • 2022 American Transplant Congress

    The Association of Pre-Transplant Dialysis Time and the Survival Benefit of Deceased Donor Kidney Transplantation

    W. F. Parker1, Y. Becker2, R. Gibbons1

    1University of Chicago, Chicago, IL, 2University of Chicago, Hinsdale, IL

    *Purpose: The US Kidney Allocation System (KAS) allows for deceased donor kidney transplant (DDKT) candidates not yet on dialysis to accrue waiting time points by…
  • 2022 American Transplant Congress

    Is Abo Incompatible Living Donor Liver Transplantation Really a Good Alternative for Pediatric Recipients?

    C. de Magnée1, L. Brunée1, R. Tambucci1, A. Pire1, I. Scheers2, E. Sokal2, P. Baldin3, F. Zech4, S. Eeckhoudt5, R. Reding1, X. Stephenne2

    1Pediatric Surgery and Transplantation Unit, Cliniques Universitaires St Luc, Brussels, Belgium, 2Pediatric Gastroenterology And Hepatology division, Cliniques Universitaires St Luc, Brussels, Belgium, 3Pathology department, Cliniques Universitaires St Luc, Brussels, Belgium, 4Institute of Experimental and Clinical Research, Université Catholique de Louvain, Brussels, Belgium, 5Laboratoire Hospitalier Universitaire de Bruxelles, Université Libre de Bruxelles, Brussels, Belgium

    *Purpose: ABO incompatible (ABOi) living donor liver transplantation (LDLT) has been proposed to compensate for donor shortage. To date, few studies have reported detailed ABOi…
  • 2022 American Transplant Congress

    The Effect of COVID-19 Pandemic in Intestinal Rehabilitation and Transplant Patients – International Multicenter Survey

    M. Segovia1, M. Fernandez2, S. Jafri3, T. Schiano4, S. Horslen5, C. Rumbo2, C. Zanfi6, A. Testro7, L. Sharkey8, F. Braun9, H. Vilca Melendez10, R. Sanchez Claria11, L. Ceulemans12, T. Hibi13, D. Ramish2, G. Noel1, G. Dijkstra14, P. Friend15, F. Lacaille16, D. Sudan1, G. Mazariegos17, J. Yap18, G. Herlenius19, H. Solar2, G. Gondolesi2

    1Duke, Durham, NC, 2Favaloro, Buenos Aires, Argentina, 3Henry Ford, Detroit, MI, 4Mount Sinai, New York, NY, 5UPMC, Edgeworth, PA, 6U Bologna, Bologna, Italy, 7Austin Health, Melbourne, Australia, 8Cambridge, Cambridge, United Kingdom, 9Schleswig-Holstein, Kiel, Germany, 10King's College, London, United Kingdom, 11Hosp Italiano, Buenos Aires, Argentina, 12U Leuven, Brussels, Belgium, 13Kumamoto Univ, Kumamoto, Japan, 14U Groningen, Groningen, Netherlands, 15U Oxford, Oxford, United Kingdom, 16Necker-Enfants Malades, Paris, France, 17UPMC, Pittsburgh, PA, 18U Melbourne, Melbourne, Australia, 19U Sahlgrenska, Gothenburg, Sweden

    *Purpose: It has been proposed that patients with intestinal failure (IF) and intestine transplant (IT) are at higher risk of severe complications of COVID-19 due…
  • 2022 American Transplant Congress

    Noroviral Diarrhea in Solid Organ Transplant Recipients: Characteristics, Interventions and Outcomes

    S. N. Nair, A. Bhaskaran, A. Chandorkar, L. Fontana, K. Obeid

    University of Minnesota, Minneapolis, MN

    *Purpose: Norovirus may result in significant morbidity in solid organ transplant (SOT) recipients. There is limited evidence for therapeutics beyond supportive care for the management…
  • 2022 American Transplant Congress

    Gm2a: A Novel Regulatory Pathway Controlling CD8+ T Cell Alloimmunity

    K. M. Baecher1, J. Bazzano1, K. Tong1, M. Fribourg2, P. Cravedi2, P. S. Heeger2, M. L. Ford1

    1Department of Surgery, Emory University, Atlanta, GA, 2Mount Sinai School of Medicine, New York, NY

    *Purpose: Transplant recipients experience lifelong immunosuppression, yet studies have shown that a subset of patients may be able to retain stable graft function even with…
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