ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Batf3 and IRF4 in Control of iTreg Differentiation, Stability, and Survival

    P. Arnold, X. Xiao, X. Zhang, M. Wen, G. Wang, X. Chu, X. C. Li

    Houston Methodist Research Institute, Houston, TX

    *Purpose: The use of in vitro-differentiated induced Tregs (iTregs) in transplantation and various diseases is a promising therapeutic that is limited by challenges to iTreg…
  • 2022 American Transplant Congress

    Ureteral Management for Kidney Transplantation in Patients with Ileal Conduit: Finger Technique

    Y. Lin, M. Eltemamy, H. Kerr, V. Krishnamurthi, D. Goldfarb, A. Wee

    Cleveland Clinic, Cleveland, OH

    *Purpose: Kidney transplantation in patients with previous urinary diversion is a surgical challenge. In patients with ileal conduit, ureteral anastomosis is not standardized.*Methods: The technique…
  • 2022 American Transplant Congress

    Induction of Tolerance After Intestinal Transplantation in a Porcine Model

    S. Merl, R. Jones, B. Chen, M. Sykes, K. Yamada, J. Weiner

    Columbia Center for Translational Immunology, Columbia University, New York, NY

    *Purpose: We describe a case of tolerance from our study investigating multilineage chimerism under immunological conditions after intestinal transplantation using a porcine model with defined…
  • 2022 American Transplant Congress

    Protective Immunity Against a Murine Epstein-Barr Virus Homolog is Preserved During CD11b-CD154 Blockade

    K. L. Alexander, D. Liu, M. L. Ford

    Emory University Transplant Center, Emory University, Atlanta, GA

    *Purpose: CD154 pathway antagonism has shown to be a promising target for inducing long-time graft survival, in some cases showing efficacy that is superior to…
  • 2022 American Transplant Congress

    Processing Personal Activity Tracker (PAT) Through Artificial Intelligence (AI) is a Promising Method to Identify Patterns of Physical Activity in Liver Transplant (LT) Candidates

    A. Duarte-Rojo1, P. M. Bloomer1, J. M. Jakicic2, E. Sejdic3

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2Adventa Health, Orlando, FL, 3University of Pittsburgh, Pittsburgh, PA

    *Purpose: Prehabilitation is recommended for frail and pre-frail LT candidates. Although home-based programs are generalizable, their success depends on the adherence to an exercise prescription.…
  • 2022 American Transplant Congress

    Early Evaluation Of The Impact Of Change In UNet Organ Refusal Code Reasons On Us Transplant Center Organ Offers

    S. Noreen1, C. Martinez1, S. Mohan2, K. McCharen1, A. Placona1, R. Patzer3

    1United Network for Organ Sharing, Richmond, VA, 2Columbia University Medical Center, New York, NY, 3Emory University, Atlanta, GA

    *Purpose: On December 2, 2021 a new set of organ refusal codes was implemented in DonorNet. These new codes were meant to provide more relevant…
  • 2022 American Transplant Congress

    Do CMS Oversight and the Systems Improvement Agreement Really Change Institutional Behavior?

    C. Hoopes

    University of Alabama Birmingham, Birmingham, AL

    *Purpose: A Systems Improvement Agreement (SIA) is a voluntary and binding legal agreement between CMS and a Medicare certified hospital designed to address Condition level…
  • 2022 American Transplant Congress

    Liver Outcomes and Equity (LOEq) Index: Neighborhood-Level Social Determinants of Health and Waitlist Disparities for Adult Liver Transplantation

    K. Zhou, L. S. Kuo, L. K. Thompson, J. L. Dodge, M. G. Cockburn, N. Terrault

    University of Southern California, Los Angeles, CA

    *Purpose: Impact of neighborhood-level social determinants of health (SDOH) among adult liver transplant (LT) candidates is largely unknown. We constructed a novel index (LOEq) to…
  • 2022 American Transplant Congress

    NK Cells in Kidney Allograft Antibody-mediated Rejection Display Increased Proliferation, IL-21 Responsiveness, Type-1 Activation, and Cytotoxic Profile

    E. Bailly1, C. Macedo1, K. Louis2, X. Gu1, B. Ramaswami1, M. Lucas1, C. Bentlejewski1, A. Zeevi1, P. Randhawa1, C. Lefaucheur2, D. Metes1

    1Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, 2INSERM UMR-S976. Endothelium, Inflammation & Alloreactivity, Paris, France

    *Purpose: The role of NK cell during antibody-mediated rejection (ABMR) has been previously recognized, but an in-depth characterization of pathways that contribute to such immune…
  • 2022 American Transplant Congress

    Heterogeneity in Center Practices in Liver Transplantation for Alcohol-Associated Liver Disease in the United States

    N. Lim1, A. Kwong2, S. Jafri3, M. Jesse3, M. Kriss4, K. Nair5, A. Pillai6, A. Shingina7, A. Desai8

    1Division of Gastroenterology, Hepatology & Nutrition, University of Minnesota, Minneapolis, MN, 2Stanford University, Palo Alto, CA, 3Henry Ford Hospital, Detroit, MI, 4University of Colorado School of Medicine, Aurora, CO, 5Community Health Network, Indianapolis, IN, 6University of Chicago, Chicago, IL, 7Vanderbilt University, Nashville, TN, 8Indiana University, Indianapolis, IN

    *Purpose: Alcohol-associated liver disease (ALD) is now the leading indication for liver transplantation (LT) in the United States (US), particularly since LT has emerged as…
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