ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Race Inequity in Liver Transplant Waitlisting: Effect Modification by Psychosocial Factors and the Stanford Integrated Psychosocial Assessment for Transplant

    S. Deutsch-Link1, L. Nephew2, E. Weinberg3, R. Weinrieb4, M. Serper3

    1Gastroenterology & Hepatology, University of North Carolina, Chapel Hill, NC, 2Gastroenterology & Hepatology, Indiana University, Chapel Hill, NC, 3Gastroenterology & Hepatology, University of Pennsylvania, Philadelphia, PA, 4Psychiatry, University of Pennsylvania, Philadelphia, PA

    *Purpose: Race inequity in liver transplantation (LT) has been a longstanding area of injustice within the field of hepatology. Information from psychosocial evaluations and The…
  • 2022 American Transplant Congress

    Fibroblastic Reticular Cell Subset Transcriptional Reprogramming Differs in Response to Immunity versus Tolerance

    L. Li1, Y. Song1, M. Shirkey1, A. Kensiski1, W. Piao1, V. Saxena1, S. Gavzy1, B. Ma1, R. Abdi2, J. Bromberg1

    1UMB, Baltimore, MD, 2Harvard University, Boston, MD

    *Purpose: Lymph node (LN) fibroblastic reticular cells (FRCs) are central contributors to the LN niche. We hypothesized that FRC subsets reactive to immunity versus tolerance…
  • 2022 American Transplant Congress

    Validation of a Hypertension Risk Calculator for Living Kidney Donors

    E. S. Helgeson1, S. Vempati1, E. F. Palzer1, G. Mjøen2, A. J. Haugen3, A. Matas4

    1Division of Biostatistics, University of Minnesota, Minneapolis, MN, 2Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, 3Department of Internal Medicine, Bærum Hospital, Sandvika, Norway, 4Department of Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: It would be ideal if candidates considering kidney donation understood their long-term risks. Using single-center data (n=4055; median [IQR] f/u: 18 [9-28] yrs), we…
  • 2022 American Transplant Congress

    Digital Spatial Profiling of Kidney Allograft Biopsies with Chronic Allograft Dysfunction in African American Transplant Recipients

    C. R. Dorr1, S. A. Elmer1, B. Wu2, B. Guo2, J. Czyzyk2, G. Crary3, G. Onyeaghala1, W. Oetting2, P. Jacobson2, R. B. Mannon4, G. Agarwal5, J. Maltzman6, A. Matas2, A. Israni3

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2University of Minnesota, Minneapolis, MN, 3Hennepin County Medical Center, Minneapolis, MN, 4Medicine, University of Nebraska Medical Center, Omaha, NE, 5University of Alabama at Birmingham, Birmingham, AL, 6Stanford University, Palo Alto, CA

    *Purpose: Understanding tissue heterogeneity is important to identify the molecular and cellular mechanisms of kidney allograft loss in African American (AA) transplant recipients. Our aim…
  • 2022 American Transplant Congress

    Higher Baseline Serum Creatinine Levels AreAssociated with an Increased Incidence of Renal Replacement Therapy in Patients with Hepatorenal Syndrome Type 1 on the Liver Transplant Waitlist

    S. N. Sclair1, A. Befeler2, K. Jamil3

    1Hepatology, University Hospitals Cleveland Medical Center & Case Western Reserve University, Cleveland, OH, 2Gastroenterology, Hepatology, Transplant Hepatology, Saint Louis University School of Medicine, St Louis, MO, 3Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ

    *Purpose: Pretransplant and posttransplant renal replacement therapy (RRT) is associated with increased morbidity and mortality in liver transplant recipients, including those with Hepatorenal syndrome type…
  • 2022 American Transplant Congress

    Pregnancy After Heart Transplant Does Not Negatively Impact Long Term Patient Survival

    M. J. Moritz1, D. Lee2, C. Madu2, S. Hossain3, L. A. Coscia4, S. Rao5, S. Constantinescu6

    1Surgery, Lehigh Valley Health Network, Allentown, PA, 2Cardiovascular Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL, 3Data Analytics, University of South Florida, Muma College of Business, Tampa, FL, 4Transplant Pregnancy Registry International, Philadelphia, PA, 5Nephrology, University of Virginia Health System, Charlottesville, VA, 6Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA

    *Purpose: To evaluate the impact of pregnancy on patient survival in heart transplant recipients (HTRs), we linked the Transplant Pregnancy Registry International (TPRI) dataset with…
  • 2022 American Transplant Congress

    Higher Immunogenicity of a Third Heterologous Dose with BNT262b2 Mensanger RNA Vaccine Compared to a Homologous Dose in Kidney Transplant Recipients Fully Vaccinated with Inactivated Whole-Virion CoronaVac Vaccine

    L. V. Pouzo1, M. Nakamura1, L. A. Viana2, E. Lucena1, M. Jesus1, G. Bittencourt Pereira Lima1, J. Medina1, H. Tedesco1, M. Cristelli1

    1Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil, 2Nephrology, Hospital do rim, Sao Paulo, Brazil

    *Purpose: This study aims to compare the immunogenicity of a third dose of the heterologous BNT262b2 mRNA vaccine versus the homologous inactivated whole-virion CoronaVac vaccine…
  • 2022 American Transplant Congress

    Autologous Mesenchymal Stem Cells for Treatment of Chronic Antibody-Mediated Kidney Graft Rejection: Report of the First Phase I/II Clinical Case Series

    Ž. Večerić-Haler1, M. Sever2, N. Kojc3, G. Mlinšek1, M. Oblak1, P. Halloran4, A. Aleš Rigler1, J. Buturović Ponikvar1, M. Arnol5

    1Nephrology, UMC Ljubljans, Ljubljana, Slovenia, 2Haematology, UMC Ljubljans, Ljubljana, Slovenia, 3Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana,, Ljubljana, Slovenia, 4Division of Nephrology and Transplant Immunology, University of Alberta, Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 5University Medical Centre Ljubljana, Ljubljana, Slovenia

    *Purpose: The aim of this study is to evaluate the safety and efficacy of autologous mesenchymal stem cellc (MSCs) in combination with standard of care…
  • 2022 American Transplant Congress

    Successful Transplantation of CPRA 95-100% HLA Incompatible (HLA I) KPD Candidates: A New Combined KPD Matching Strategy at a Single Centre

    H. Helwani1, D. Broering2, I. Alahmadi3, T. Ali1, F. Alzayer4, M. Mankowski5, A. Algharabli1

    1Kidney & Pancreas Health Centre, OTCoE, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 2Organ Transplant Centre of Excellence, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 3Kidney & Pancreas Transplant Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 4King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 5King Abdullah University for Science & Technology, Saudi Arabia, Saudi Arabia

    *Purpose: The six components of the new strategy are Universal flexible assignments of unacceptable antigens (UA); individualized deletion of carefully selected UA; inclusion of compatible…
  • 2022 American Transplant Congress

    Preoperative Antibiotics Administration is Important to Prevent Hand Port-Site Infection After Hand-Assisted Laparoscopic Donor Nephrectomy for Living-Donor Kidney Transplantation

    T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, N. Goto, T. Ichimori, S. Narumi, Y. Watarai

    Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan

    *Purpose: Due to the profound organ shortage, the number of living donor kidney transplantation (LDKT) is increasing. Hand-assisted laparoscopic donor nephrectomy (HALDN) is widely performed…
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