ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    A Novel, High Throughput Droplet Digital PCR-Based Indel Quantification Method for the Detection of Circulating Donor-Derived Cell-Free DNA After Kidney Transplantation

    J. G. Verhoeven1, K. Boer1, A. M. Peeters1, M. C. Clahsen-van Groningen2, J. I. Roodnat1, J. van de Wetering1, D. Nieboer3, D. A. Bost4, C. C. Baan1, D. A. Hesselink1

    1Department of Internal Medicine, Erasmus MC Transplant Institute, Rotterdam, Netherlands, 2Department of Pathology, University Medical Center Rotterdam, Rotterdam, Netherlands, 3Department of Public Health, University Medical Center Rotterdam, Rotterdam, Netherlands, 4JETA Molecular, Utrecht, Netherlands

    *Purpose: Donor-derived cell-free DNA (ddcfDNA) is a promising minimally invasive biomarker for acute rejection (AR) in kidney transplant recipients. To assess the diagnostic value of…
  • 2022 American Transplant Congress

    Peripheral Blood Immune Cell Profiles of Corneal Transplant with and without Acute Rejection

    J. Hjortdal1, M. Griffin2, C. C. Murphy3, S. Brouard4, N. Degauque4

    1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark, 2National University of Ireland, Galway, Galway, Ireland, 3Royal Victoria Eye and Ear Hospital, Dublin, Ireland, 4Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France

    *Purpose: Acute rejection (AR) of allogeneic corneal transplantation (CT) has a profound effect on subsequent graft survival, indicating that immunological damage is often not fully…
  • 2022 American Transplant Congress

    Impact of Sars-CoV-2 Vaccination on Donor-Derived Cell Free DNA Levels in Renal Transplant Recipients

    H. Alvarado Verduzco, E. Daniel, D. Kim, A. Hussain, S. Mohan, D. Cohen

    Columbia University Irving Medical Center, New York, NY

    *Purpose: COVID-19 poses a disproportionate threat to renal transplant recipients (RTR), who are chronically immunosuppressed. Studies have indicated a 16% mortality rate compared to
  • 2022 American Transplant Congress

    Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial

    M. M. Pascale1, G. Bianco1, L. Ferri1, F. Giovinazzo1, A. Liguori2, G. Marrone2, A. Grieco2, S. Agnes1

    1General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, 2Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy

    *Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…
  • 2022 American Transplant Congress

    Predictive Value of Abnormal Hemodynamic Response to Dobutamine Stress Echocardiography in Liver Transplant Recipients

    M. Groose, A. Peotter, L. Hammel

    University of Wisconsin Hospitals and Clinics, Madison, WI

    *Purpose: Dobutamine stress echocardiography (DSE) is an effective tool for perioperative cardiac risk stratification in patients without end-stage liver disease (ESLD). However, DSE is frequently…
  • 2022 American Transplant Congress

    Resource Utilization in Liver Transplant Patients Based on Psychological Evaluation of High Risk vs. Non-High Risk

    K. Barber1, D. Chism2, R. Sauls3, R. Shargo3, M. Gosselin4, S. Mohammed3, K. Robichaux3, A. Kumar5, J. Buggs1

    1Transplant Surgery, Tampa General Hospital, Tampa, FL, 2Lake Erie College of Osteopathic Medicine, Bradenton, FL, 3University of South Florida, Tampa, FL, 4University of Tampa, Tampa, FL, 5Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Psychological evaluation in liver transplant candidates helps to determine suitability. The psychological risk assessment results in the characterization of either low, medium, or high…
  • 2022 American Transplant Congress

    DCD Liver Grafts Can Safely be Used for Recipients with Grade 1-2 Portal Vein Thrombosis

    L. A. Mercado1, H. K. Bhangu1, K. R. Musto2, K. D. Watt3, B. Taner4, C. B. Rosen5, T. Taner5, L. Yang1, D. M. Harnois1, J. D. LeGout6, K. P. Croome4

    1Liver Transplant, Mayo Clinic, Jacksonville, FL, 2Transplant, Mayo Clinic, Jacksonville, FL, 3Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 4Transplant Surgery, Mayo Clinic, Jacksonville, FL, 5Transplant Surgery, Mayo Clinic, Rochester, MN, 6Radiology, Mayo Clinic, Jacksonville, FL

    *Purpose: Limited data is available in the literature regarding patients with portal vein thrombosis (PVT) receiving a liver transplant (LT) from a donation after circulatory…
  • 2022 American Transplant Congress

    Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants

    S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King

    Surgery, Johns Hopkins University, Baltimore, MD

    *Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
  • 2022 American Transplant Congress

    National Landscape of the Utilization of Living Donor Liver Allografts in Redo Liver Transplantation

    J. I. López, K. Nijhar, J. Mitchell, L. Bowles Zeiser, K. Key, A. Asamoah-Mensah, A. Thomas, R. Haneda, S. K. Romano, J. Huang, A. Massie, A. M. Cameron, D. L. Segev, E. A. King

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: To examine the use of living donor liver allografts in patient’s requiring redo liver transplantation.*Methods: Using data from SRTR 2009-2020, we evaluated the number…
  • 2022 American Transplant Congress

    Impact of Graft Type, Presence and Type of Inflammatory Bowel Disease on Outcomes Following Liver Transplantation for Primary Sclerosing Cholangitis

    S. Kumar1, S. Lin2, J. D. Schold3

    1Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 2Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Center for Populations Health Research, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: In Primary sclerosing cholangitis (PSC), concerns exist regarding outcomes following donation after circulatory death (DCD) liver transplantation (LT) due to risk of ischemic cholangiopathy…
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