ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Impact of Removing DSA and OPTN Region from Pancreas Allocation

    S. E. Booker1, A. Robinson1, K. Gauntt1, J. White1, S. Niederhaus2, O. Olaitan3, R. Forbes4

    1UNOS, Richmond, VA, 2University of Maryland School of Medicine, Baltimore, MD, 3Rush University Medical Center, Chicago, IL, 4Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Donation Service Area (DSA) and OPTN Region were removed from pancreas allocation on 3/15/21 and replaced with a 250 nautical mile (NM) fixed circle…
  • 2022 American Transplant Congress

    Direct Oral Anticoagulants versus Warfarin in Adult Heart Transplant Recipients

    L. Shitanishi, A. Fan, T. Khuu, R. Ardehali

    University of California Los Angeles, Los Angeles, CA

    *Purpose: Direct oral anticoagulants (DOACs) have recently transformed the field of anticoagulation, offering more predictable pharmacokinetic and pharmacodynamic characteristics when compared to traditional warfarin therapy.…
  • 2022 American Transplant Congress

    De Novo Donor-Specific Antibody Development in Heart Transplant Recipients Following COVID-19 Vaccination

    M. Cheng1, O. Behbahani-Nejad1, D. Gupta2

    1Internal Medicine, Emory University School of Medicine, Atlanta, GA, 2Internal Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA

    *Purpose: To determine the incidence of de novo donor-specific antibodies (DSAs) in recipients of orthotopic heart transplants (OHT) who received an mRNA vaccine against SARS-CoV-2.*Methods:…
  • 2022 American Transplant Congress

    Biological Functions of Circulating miRNAs in Patients with Chronic Pancreatitis Undergoing Total Pancreatectomy with Islet Autotransplantation

    S. Vasu1, C. Darden2, Y. Liu3, M. Lawrence4, B. Naziruddin1

    1Baylor University Medical Ctr, Dallas, TX, 2Baylor University, Waco, TX, 3-Baylor University Medical Center, Dallas, TX, 4Baylor University Medical Center, Dallas, TX

    *Purpose: Our previous reports showed that in patients with Chronic Pancreatitis (CP), specific microRNAs (miRNA) were elevated in circulation before, during islet infusion and after…
  • 2022 American Transplant Congress

    Meld 3.0 for Liver Allocation: Results From the Liver Simulated Allocation Model

    A. Kwong1, T. Weaver2, D. Schladt2, A. Wey2, K. Audette2, S. Biggins3, J. Snyder2, A. Israni2, J. Lake4, W. Kim1

    1Stanford University, Stanford, CA, 2Hennepin Healthcare Research Institute, Minneapolis, MN, 3University of Washington, Seattle, WA, 4University of Minnesota, Minneapolis, MN

    *Purpose: Priority on the US liver transplant waitlist is determined by the model for end-stage liver disease (MELD), a score composed of serum bilirubin, creatinine,…
  • 2022 American Transplant Congress

    Very Low Frequency of Pathological Findings in One-Year Protocol Biopsies of Low-Risk Kidney Transplant Recipients – Results from the Nordic Protocol Biopsy Study

    I. Helanterä1, C. Dörje2, F. Ortiz3, A. Varberg Reisæter2, C. Hammarstrøm2, J. Lauronen4, A. Räisänen-Sokolowski5, A. J. Haugen6, M. Lempinen1, A. Åsberg2, G. Mjøen2

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland, 2Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, 3Nephrology, Helsinki University Hospital, Helsinki, Finland, 4Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland, 5Department of Pathology, Helsinki University Hospital, Helsinki, Finland, 6Medical Department, Bærum Hospital, Bærum, Norway

    *Purpose: The clinical usefulness of kidney graft protocol biopsies have been debated. We studied the frequency of borderline and T-cell-mediated rejection (TCMR) in one-year protocol…
  • 2022 American Transplant Congress

    The Acuity Circle Allocation Policy is Associated with Worse Graft Survival After Liver Transplant with Donation After Circulatory Death Donors in Low-MELD Centers

    T. Kitajima1, T. Ivanics2, D. Moonka1, M. Shamaa1, A. Mohamed3, S. Shimada1, K. Collins4, M. Rizzari1, A. Yoshida1, M. Abouljoud4, S. Nagai1

    1Henry Ford Hospital, Detroit, MI, 2Surgery, Henry Ford Hospital, Detroit, MI, 3Department of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, 4Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Liver allocation in the United States was updated in February of 2020, with introduction of the acuity circle (AC) model. However, the effect of…
  • 2022 American Transplant Congress

    CoVID-19 Vaccine Efficacy in Heart Transplant Recipients, a Single Center Experience

    M. Yu1, S. B. Sharmin2, C. Joyce3, Z. Pieters1, S. DeSirkar1, M. Thomas1, S. Kim1, E. Bruno1, M. Liebo1, A. Heroux4, N. Clark1, G. Reid1, S. Uprichard2

    1Loyola University Medical Center, Maywood, IL, 2Microbiology and Immunology, Loyola University Chicago, Chicago, IL, 3Department of Public Health Sciences, Loyola University Chicago, Chicago, IL, 4Loyola Univ Medical Ctr, Maywood, IL

    *Purpose: Transplant recipients have worse CoVID-19 survival compared to the general population, and thus are recommended to be vaccinated and boosted. Determinants of vaccination efficacy…
  • 2022 American Transplant Congress

    BK Polyomavirus and Cytomegalovirus Infections in Kidney Transplantation from Hepatitis C Positive Donors to Uninfected Recipients

    I. Yakubu, V. Amrutiya, I. Moinuddin, M. Levy, G. Gupta, A. Azhar

    Virginia Commonwealth University, Richmond, VA

    *Purpose: Transplantation of hepatitis C viremic (HCV) donor kidneys into uninfected recipients (D+/R-) is becoming more common in the United States. However, the long-term risks…
  • 2022 American Transplant Congress

    Novel Immune Checkpoint Molecule TIGIT Mediates Experimental Kidney Ischemia Reperfusion Injury

    S. Noel, K. Lee, S. Gharaie, J. T. Kurzhagen, H. Rabb

    Medicine, Johns Hopkins University, Baltimore, MD

    *Purpose: T cells play both pathogenic and reparative roles in kidney ischemia reperfusion injury (IRI) but the molecular mechanisms regulating kidney T cell functions are…
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