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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pre-Transplant Frailty Predicts Infection After Liver Transplant in a Multi-Center Study of Older Adults

    M. Malinis1, M. Abidi2, E. Benamu2, N. Jakharia3, N. Law4, R. Sigler4, R. Nog5, S. Olivier5, S. Taimur6, N. Theodoropoulos7, J. Schaenman8

    1Yale SOM, New Haven, CT, 2Univ of CO, Aurora, CO, 3Stanford, Palo, Alto, CA, 4UCSD, San Diego, CA, 5Westchester Med Ctr, Westchester, NY, 6Mount Sinai SOM, New York, NY, 7Univ of MA, Worcester, MA, 8UCLA, Los Angeles, CA

    *Purpose: Frailty is a complex multi-system characterization of reduced physiologic reserve and functional decline in older adults. At the time of transplant, frailty has been…
  • 2022 American Transplant Congress

    Hepatocyte SIRT1 Regulation of Apoptosis-Mediated Pyroptosis Cell Death in Mouse and Human Liver Transplantation

    K. Kadono1, H. Hirao1, H. Kojima1, K. J. Dery1, X. Li2, J. Kupiec-Weglinski1

    1UCLA Medical Center, Los Angeles, CA, 2NIEHS, Durham, NC

    *Purpose: Cold static preservation is a gold-standard in orthotopic liver transplantation (OLT). However, the role of hepatocyte-specific SIRT1 transcriptional regulation of cell death programs during…
  • 2022 American Transplant Congress

    Novel Role of CD74 in Regulatory T Cell Homeostasis and Function in Allo-Immune Response

    Z. Solhjou1, H. Zhang1, N. Younis1, J. Choi1, C. Deban1, A. Saad1, A. Halawi1, Z. Jing1, R. Bucala2, J. Azzi1

    1Brigham and Women's Hospital, Boston, MA, 2Yale University School of Medicine, New Haven, CT

    *Purpose: Identifying new molecular targets based on our understanding of the biology of the allo-immune response in the allograft microenvironment is critical to develop more…
  • 2022 American Transplant Congress

    Il-33 Induced Regulatory Macrophages Inhibit Transplantation Immune Rejection by Inducing Tregs

    J. Wu, F. Zhang, W. Wang

    Beijing Chaoyang Hospital, Beijing, China

    *Purpose: The occurrence of acute and chronic rejections after transplantation are key factors that affect the survival of the recipients. Induction of transplantation immune tolerance…
  • 2022 American Transplant Congress

    Robotic Partial Nephrectomy in Transplanted Kidney

    A. Kaviani, M. Abou Zeinab, M. Noble, Y. Lin, A. Wee, J. Kaouk, M. Eltemamy

    Cleveland Clinic, Cleveland, OH

    *Purpose: To present, in a video format, the technical considerations for performing a robotic partial nephrectomy in a transplanted kidney.*Methods: Two patients underwent this procedure.…
  • 2022 American Transplant Congress

    Miami Protocol for Liver Deceased Donors After Circulatory Death: Increased 1-year Overall Survival for Selected Patients

    V. Venkatasamy, P. Abreu, J. Riella, R. Miyashiro, A. Tector, A. Tekin, G. Selvaggi, R. Vianna

    University of Miami, Jackson Memorial Hospital, Miami Transplant Institute, Miami, FL

    *Purpose: The use of deceased donors after circulatory death (DCD) for liver transplantation (LT) is still underutilized. It provides an acceptable solution to increase the…
  • 2022 American Transplant Congress

    Abdominal Incision Technique Tailored to Patient’s Age May Reduce the Rate of Surgical Wound Complication After Unilateral Kidney Transplantation- A Preliminary Report

    Y. AlSalmay, P. Bachul, B. Juengel, J. Kumar, A. Perez-Guttierez, R. Barth, J. Fung, P. Witkowski

    University of Chicago, Chicago, IL

    *Purpose: Previously, we compared the risk of abdominal wound complications after lateral rectus incision sheath (LRS) versus traditional Gibson incision in a retrospective analysis of…
  • 2022 American Transplant Congress

    Cytomegalovirus Prophylaxis in Pediatric Liver Transplantation: A Comparison of Strategies Across the SPLIT Consortium

    E. D. Knackstedt1, S. G. Anderson2, R. Anand2, J. Mitchell2, J. Bucuvalas3, L. Danziger-Isakov4

    1Univ of Utah/Primary Children's Hosp, SLC, UT, 2Emmes, Rockville, MD, 3Icahn School of Med at Mount Sinai, New York City, NY, 4Cincinnati Children's Hosp Med Ctr, Cincinnati, OH

    *Purpose: To compare the effectiveness of short (180d) cytomegalovirus (CMV) prophylaxis in pediatric liver transplantation (pLTX).*Methods: A prospective cohort study of primary pLTX (≤18 yrs…
  • 2022 American Transplant Congress

    Differing Gene Expression Profiles and Signaling Pathways Observed Between Alloreactive and Tolerant T Cells in a Recipient Following Bilateral Orthotopic Lung Transplant (BOLT) and Bone Marrow Transplant (BMT) from the Same Cadaveric UNOS Donor

    P. Szabolcs, E. Garchar, D. Rajasundaram, X. Chen

    UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA

    *Purpose: Primary immunodeficiency (PID) patients may develop pulmonary complications, and most are ineligible for either BOLT or BMT due to futility. A prospective trial in…
  • 2022 American Transplant Congress

    Assessment of Circulating B Cell Developmental Stages Early After Kidney Transplantation. Preliminary Data from a Single Center

    A. Fouza1, A. Fylaktou2, A. Xohelli2, E. Sampani3, B. Nikolaidou2, D. Asouhidou2, N. Antoniadis1, E. Kasimatis3, M. Stangou3, G. Tsoulfas1, A. Papagianni3

    1Division of Transplantation, Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece, 2National Peripheral Histocompatibility Center, Immunology Department, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece, 3Department of Nephrology, Aristotle University of Thessaloniki, Thessaloniki, Greece

    *Purpose: B lymphocytes (BL) is an important immune component in the function of kidney transplants, through antibody production, antigen-presentation to T cells, secretion of cytokines,…
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