ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Passenger Lymphocyte Syndrome Presented as Hemolytic Anemia After Small Bowel Transplantation: A Case Report

    M. Kim1, D. Kim1, J. Lim1, J. Jung2, J. Kim3, J. Hwang1

    1Eunpyeong St. Mary's Hospital, Eunpyeong-gu, Seoul, Korea, Republic of, 2Seoul St. Mary's Hospital, Seoul, Korea, Republic of, 3Uijeongbu Eulji Medical Center, Uijeongbu, Korea, Republic of

    *Purpose: The passenger lymphocyte syndrome (PLS) induces hemolytic anemia after minor ABO mismatched organ transplantation. We experienced a case of PLS with hemolysis after small…
  • 2022 American Transplant Congress

    Analysis of Tissue and Effluent Damage Associated Molecular Patterns Following Hypothermic Oxygenated Machine Perfusion vs Static Cold Storage in Liver Transplantation

    G. G. Panayotova, Y. Qin, S. Simonishvili, T. Ayorinde, F. Paterno, L. Brown, A. Amin, K. E. Lunsford, J. V. Guarrera

    Transplant Surgery, Rutgers New Jersey Medical School, Newark, NJ

    *Purpose: Hypothermic Oxygenated Machine Perfusion (HMP-O2) results in decreased ischemia/reperfusion injury (IRI) after liver transplantation; however, the molecular pathways of protection are largely unexplored. In…
  • 2022 American Transplant Congress

    Intrinsic DEPTOR Activity Modulates Treg Subset Differentiation

    J. Wedel1, M. Maslyar1, B. Alsairafi1, S. Kong2, D. M. Briscoe1

    1Transplant Research Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, 2Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA

    *Purpose: We have previously reported that DEPTOR activity within CD4+Foxp3+ Tregs increases immunomodulation following transplantation. DEPTOR functions by both stabilization of Foxp3 expression through epigenetic…
  • 2022 American Transplant Congress

    Influence of Immunosuppressive Drugs on Nk Cells in Therapeutic Drug Exposured

    R. r. Qin1, C. Sun2, B. Nashan1

    1Division of Life and Medicine, University of Science and Technology of China/The First affiliated hospital of University of Science and Technology of China, Hefei, China, 2Division of Life and Medicine, University of Science and Technology of China, Hefei, China

    *Purpose:Natural killer (NK) cells as part of the innate immune system are residing in the liver and are considered to be main regulators in alloimmune…
  • 2022 American Transplant Congress

    Risk Factors for Extubation Failure Post- Lung Transplantation

    A. J. Trindade1, W. D. Gannon1, A. G. Dragnich1, G. Dahlberg1, C. T. Demarest2, E. S. Lambright2, K. A. McPherson1, S. G. Norfolk1, C. M. Shaver1, I. M. Robbins1, M. Bacchetta2

    1Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Extubation delays following lung transplantation can result in delirium, deconditioning, infections, and increased hospital length of stay. Risk stratifying patients for extubation failure may…
  • 2022 American Transplant Congress

    Plasmapheresis Dependent AT1R Antibody Associated Recurrent FSGS After Living Donor Kidney Transplantation

    R. K. Mallavarapu

    Transplant Nephrology, Augusta University - Medical College of Georgia, Augusta, GA

    *Purpose: Antibodies against Angiotensin II type 1 receptors (AT1R-Abs) may predispose to podocyte injury, glomerular endotheliosis and proteinuria. The management of AT1R-Ab associated recurrent FSGS…
  • 2022 American Transplant Congress

    Body Composition and Relationship to Food Scarcity in Kidney Transplant Recipients (KTRS)

    S. Martinez-Machado, C. Canning, B. Sherman, L. Wei, A. Gidon, P. Flynn, M. Markell

    SUNY Downstate Health Sciences University, Brooklyn, NY

    *Purpose: Pts with food scarcity often have poor dietary habits which can result in changes in body composition, including increased or decreased body fat depending…
  • 2022 American Transplant Congress

    Protein and Transcriptomic Differences Between High and Low Neointimal Arteries in Human Cardiac Allograft Vasculopathy Rejected Grafts

    J. Nevarez-Mejia1, H. C. Pickering1, R. A. Sosa1, R. P. Lau1, G. A. Fishbein1, W. M. Baldwin III2, R. L. Fairchild2, E. F. Reed1

    1University of California, Los Angeles, Los Angeles, CA, 2Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH

    *Purpose: Cardiac allograft vasculopathy (CAV) is the leading cause of graft failure and mortality following heart transplantation. Donor specific antibodies (DSA) contribute to CAV progression…
  • 2022 American Transplant Congress

    Atherosclerosis Reduces Anti-Tumor Activity of Liver-Resident Natural Killer Cells

    K. Imaoka, M. Ohira, K. Sato, Y. Imaoka, R. Nakano, H. Ohdan

    Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

    *Purpose: Abdominal aorta calcification (AAC) is associated with an increased relative risk of coronary events, cerebrovascular events, cardiovascular events, and cardiovascular death. We report that…
  • 2022 American Transplant Congress

    Alemtuzumab and Basilximab Induction Therapy in Lung Transplantation

    M. Furukawa, E. Chan, P. G. Sanchez

    Cardiothoracic Surgery, UPMC, Pittsburgh, PA

    *Purpose: Induction therapy is used in about more than 80% of lung transplant centers and is increasing globally. Currently, there are no standards or guideline…
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