ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Complete and High-Resolution HLA Typing Improves the Accuracy of Post-Transplant Assessment of De Novo Anti-Donor Immune-Mediated Events

    M. Meneghini1, A. Perona2, E. Crespo3, F. J. Bemelman4, P. M. Reinke5, O. Viklicky6, M. Giral7, O. Bestard1

    1Vall d'Hebron University Hospital, Barcelona, Spain, 2Universitat de Barcelona, Barcelona, Spain, 3Nephrology and Transplantation Laboratory, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, 4Amsterdam University Medical Centers, Amsterdam, Netherlands, 5Charité Universitätsmedizin, Berlin, Germany, 6Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, 7Nantes Université, Inserm, CHU Nantes, Nantes, France

    *Purpose: High-resolution (HR) HLA typing using NGS technology has shown to improve the accuracy of assessing donor-recipient compatibility and characterization of pre-transplant anti HLA antibodies…
  • 2022 American Transplant Congress

    Establishment of an In Vitro Assay to Evaluate Indirect T-cell Allo-Response Using Donor PBMC-Pulsed Dendritic Cells

    K. Iwasaki1, T. Tomosugi2, T. Sekiya3, H. Hamana4, Y. Miwa1, K. Futamura2, M. Okada2, T. Hiramitsu2, N. Goto2, S. Narumi2, Y. Watarai2, H. Kishi4, M. Okumura5, S. Ashimine5, K. Ishiyama5, T. Kobayashi5

    1Department of Kidney Diseases and Transplant Immunology, Aichi Medical University School of Medicine, Nagakute, Japan, 2Department of Transplant Surgery, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan, 3Department of Immune Regulation, The Research Center for Hepatitis and Immunology, Ichikawa, Japan, 4Department of Immunology, University of Toyama, Toyama, Japan, 5Department of Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Japan

    *Purpose: Conventional MLR-based methods which evaluate donor-specific immune response via direct T-cell recognition pathway have been reported to be useful in predicting acute TCMR. However,…
  • 2022 American Transplant Congress

    Outcomes in Kidney Transplant Recipients 70 Years and Older

    J. Mehta, N. F. Okonkwo, A. Paramesh, K. Atiemo, M. Killackey, H. Jeon, A. Vijay

    Tulane University School of Medicine, New Orleans, LA

    *Purpose: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in…
  • 2022 American Transplant Congress

    Portal-Endocrine and Gastric-Exocrine Drainage Technique in Pancreatic Transplantation

    H. Shokouh-Amiri1, M. S. Naseer2, R. McMillan1, D. Aultman1, S. Tandukar1, N. Singh1, G. B. Zibari1

    1John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, 2Transplant, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA

    *Purpose: Diagnosis of rejection has continued to be problematic in pancreas transplantation (PT). In 2007, we innovated a new surgical technique for PT, portal-endocrine and…
  • 2022 American Transplant Congress

    Solid Organ Pancreas Transplantation Offers Superior Glycemic Control Compared to State of the Art Insulin Delivery with Continuous Glucose Monitoring (CGM)

    K. R. McCune, G. K. Dube, P. R. Sandoval, L. E. Ratner

    Columbia University, New York, NY

    *Purpose: Advanced insulin delivery systems with CGM fail to keep serum glucose within range (70-180 mmol/L) 30-40% of the time resulting in Hgb A1C goals…
  • 2022 American Transplant Congress

    Phenytoin To Expedite Sirolimus & Tacrolimus Elimination: A Case Report

    A. Lemke, B. A. Boilson, R. Razonable, S. A. Bernard

    Mayo Clinic, Rochester, MN

    *Purpose: Sirolimus (SIR), a mammalian target of rapamycin inhibitor (mTORi), may be used with or without a calcineurin inhibitor after heart transplant (HT). The anti-proliferative…
  • 2022 American Transplant Congress

    Outcomes and Complications of Covid-19 in Pediatric Solid Organ Transplant Patients

    L. Ott, P. Scalise, B. Kimball, A. G. Cuenca

    Department of Surgery, Boston Children's Hospital, Boston, MA

    *Purpose: The purpose of the study was to examine the clinical course, outcomes, and complications of COVID-19 in pediatric solid organ transplant patients from a…
  • 2022 American Transplant Congress

    Impact of Cytomegalovirus Infection on mRNA Expression Utilizing the Molecular Microscope in Heart Transplant Recipients

    S. S. Patlolla, J. Van Zyl, K. Castro, S. Mckean, R. Patel, S. Carey, A. Alam, S. Hall

    Cardiology, Baylor University Medical Center, Dallas, TX

    *Purpose: Little is known about the effect of CMV infection on transplant messenger RNA expression utilizing the molecular microscope (MMDx) in the absence of acute…
  • 2022 American Transplant Congress

    Impact of Immunosuppression on T-cell Responses After mRNA-Based Sars-CoV-2 Vaccination

    E. Wong1, N. L. Bert2, H. K. Sran1, A. Lim1, M. D'Costa1, K. Akalya2, S. Hang2, A. Bertoletti2, A. Vathsala1

    1National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore, 2Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore

    *Purpose: Administration of mRNA-based SARS-CoV-2 vaccines confers protection from SARS-CoV-2 infection and reduces its severity in the general population. It has been suggested that mounting…
  • 2022 American Transplant Congress

    Sex- and Insurance- Based Disparities in Listing for and Benefit from Simultaneous Heart-Kidney Transplant

    B. Wayda1, X. S. Cheng1, P. Garcia1, S. Sanoff2, L. M. McElroy2, K. K. Khush1

    1Stanford University School of Medicine, Stanford, CA, 2Duke University School of Medicine, Durham, NC

    *Purpose: Rates of simultaneous heart-kidney (SHK) transplant vary widely in the United States (US). Absent uniform eligibility criteria, sex and insurance status could influence patient…
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