2022 American Transplant Congress
cDC1-Mediated Prolongation of Cardiac Allograft Survival and Alloantigen Induced Transcriptional Programming
Pathology, Northwestern Feinberg School of Medicine, Chicago, IL
*Purpose: Heart transplantation is currently the only treatment for advanced stage heart failure. While patient survival after transplantation has improved acutely, the same cannot be…2022 American Transplant Congress
High-Throughput Immune Synapse Detection as a Tool for the Measurement of T Cell Alloreactivity in Humans
University Health Network, Toronto, ON, Canada
*Purpose: Accurate measurement of T cell alloreactivity may allow prediction of graft outcome and the selection of patients for immunosuppression optimization. Current technologies cannot reliably…2022 American Transplant Congress
Surging Liver Transplant Rates for Alcohol-Associated Liver Disease May Exacerbate Waitlist Death of Patients with Hepatocellular Carcinoma in MMAT-3 Era
*Purpose: Rates of liver transplantation (LT) for alcohol-associated liver disease (ALD) have increased significantly, in part related to broader acceptance of severe alcohol hepatitis (AH)…2022 American Transplant Congress
Association of Change in Kidney Volume with Proteinuria After Donation
*Purpose: In living kidney transplantation, the risk of end-stage kidney disease in kidney donors is crucial, however, it still remains to be resolved. Any useful…2022 American Transplant Congress
Evaluation of UW-Based Solutions Formulated to Be Anti-Apoptotic and Neuroprotective of Retinal Ganglion Cells (RGCs) Following Whole Eye Transplantation (WET) in a Rat Model
*Purpose: As vascularized composite allotransplantation (VCA) of an intact optical system to restore vision requires overcoming RGC apoptosis caused by ischemia reperfusion injury, UW and…2022 American Transplant Congress
Complete and High-Resolution HLA Typing Improves the Accuracy of Post-Transplant Assessment of De Novo Anti-Donor Immune-Mediated Events
*Purpose: High-resolution (HR) HLA typing using NGS technology has shown to improve the accuracy of assessing donor-recipient compatibility and characterization of pre-transplant anti HLA antibodies…2022 American Transplant Congress
Establishment of an In Vitro Assay to Evaluate Indirect T-cell Allo-Response Using Donor PBMC-Pulsed Dendritic Cells
*Purpose: Conventional MLR-based methods which evaluate donor-specific immune response via direct T-cell recognition pathway have been reported to be useful in predicting acute TCMR. However,…2022 American Transplant Congress
Outcomes in Kidney Transplant Recipients 70 Years and Older
Tulane University School of Medicine, New Orleans, LA
*Purpose: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in…2022 American Transplant Congress
Portal-Endocrine and Gastric-Exocrine Drainage Technique in Pancreatic Transplantation
*Purpose: Diagnosis of rejection has continued to be problematic in pancreas transplantation (PT). In 2007, we innovated a new surgical technique for PT, portal-endocrine and…2022 American Transplant Congress
Solid Organ Pancreas Transplantation Offers Superior Glycemic Control Compared to State of the Art Insulin Delivery with Continuous Glucose Monitoring (CGM)
Columbia University, New York, NY
*Purpose: Advanced insulin delivery systems with CGM fail to keep serum glucose within range (70-180 mmol/L) 30-40% of the time resulting in Hgb A1C goals…
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