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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Chronic Active Antibody Mediated Rejection: 3 Month Response Rates to Treatment and Predictors of Graft Survival

    F. Aziz, M. Jorgenson, S. Parajuli, N. Garg, V. Manchala, E. Yousif, D. Mandelbrot, L. Hidalgo, M. Mohamed, W. Zhong, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: There is limited information on effectiveness of treatment and predictors of graft survival following chronic active antibody mediated rejection (cABMR) in kidney transplant recipients…
  • 2022 American Transplant Congress

    Implementing Genetic Testing in the Evaluation of the Kidney Transplant Candidate

    F. Abu Al Rub1, Y. Caliskan2, H. Randall2, B. Bastani2, V. Fleetwood3, M. Nazzal2, C. Varma2, K. Lentine2

    1St. Louis University, St Louis, MO, 2St. Louis University, St. Louis, MO, 3Department of Transplantation, St. Louis University, St. Louis, MO

    *Purpose: To describe the incorporation of a genetic renal panel to improve the characterization of end stage kidney disease (ESKD) etiology in the kidney transplant…
  • 2022 American Transplant Congress

    Measurement of Physical Activity and Frailty in the Early Post-Operative Period After Kidney Transplant-Single-Center Prospective Pilot Study Using Fitbit Watch

    T. Shamaa, L. Allenspach, O. Shamaa, S. Shimada, C. Crombez, O. Hage-Hassan, T. Kitajima, S. Yeddula, I. Bajjoka, L. Malinzak, J. Denny, D. Kim, M. Abouljoud, S. Nagai

    Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Physical activity monitors (PAMs) allow patients to track multiple health parameters. PAM’s may be helpful to assess a patient’s physical recovery after a Kidney…
  • 2022 American Transplant Congress

    Mitochondrial Transplant as Novel Therapeutic Modality to Reduce Nonalcoholic Fatty Liver Disease

    M. Namwanje1, A. Stayton1, C. White1, C. Kuscu1, C. Kuscu1, J. Eason2, A. Bajwa1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Mitochondrial dysfunction in adipose tissue is one of the mechanisms contributing to obesity and its co-morbidities. Transfer of healthy mitochondria has proven successful in…
  • 2022 American Transplant Congress

    Neutrophil CEACAM1 Regulates Extracellular Trap Formation via Non-Canonical Inflammasome Signaling and Impacts Liver Transplantation in Mouse and Human

    H. Hirao, H. Kojima, K. Kadono, K. J. Dery, D. G. Farmer, F. M. Kaldas, J. Kupiec-Weglinski

    UCLA, Los Angeles, CA

    *Purpose: Neutrophil extracellular trap (NET) formation relates to various diseases, including sterile inflammation. Although neutrophils express proficient CEACAM1 (CC1, also known as CD66a) long isoform,…
  • 2022 American Transplant Congress

    Lung Transplant Waitlist Outcomes for Blood Group O Candidates After the Expansion of the Primary Allocation Unit in November 2017

    S. Greissman1, M. Anderson2, S. Arcasoy3, A. Dimango3, M. Gabriela3, H. Grewal3, H. Robbins3, L. Shah3, J. Costa3, F. D'Ovidio3, M. Leiva Juarez3, P. Lemaitre3, J. Sonett3, L. Benvenuto3

    1Department of Internal Medicine, New York Presbyterian, New York, NY, 2University of Pennsylvania, Philadelphia, PA, 3Columbia University, New York, NY

    *Purpose: Blood group O is associated with decreased lung transplant rates. Occasionally, blood group donor O lungs are allocated to non-blood group O recipients. Since…
  • 2022 American Transplant Congress

    Broad Panel Genetic Testing for Chronic Kidney Disease in the Transplant Center

    A. Bhalla1, D. Raible2, V. Balaraman1, M. Talwar1

    1James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN, 2Natera, Inc., Austin, TX

    *Purpose: Genetic testing is an emerging tool for ‌the evaluation of patients with end-stage renal disease (ESRD). In kidney transplantation (KT), testing can identify disease…
  • 2022 American Transplant Congress

    Absolute Quantification of Donor-Derived Cell-Free DNA Does Not Provide Additional Discriminating Power Over Donor-derived Cell-Free DNA Fraction for Detection of Allograft Rejection

    R. Gohh1, S. Jordan2, R. N. Woodward3, K. M. Clark-Langone3, J. Morlan3, B. Silva3, M. Weir4

    1Alpert School of Medicine Brown University, Providence, RI, 2Cedars Sinai Medical Ctr, Los Angeles, CA, 3CareDx, Redwood City, CA, 4University of Maryland School of Medicine, Baltimore, MD

    *Purpose: High level of background cell-free DNA (cfDNA) has been hypothesized as a concern for false negative results in molecular diagnostics for allograft rejection that…
  • 2022 American Transplant Congress

    The Perspective of General Nephrologists Toward Transitions of Care and Management of Patients with Failing Kidney Allografts

    T. Alhamad1, H. Murad1, D. Dadhania2, M. Pavlakis3, S. Parajuli4, B. P. Concepcion5, N. Singh6, N. Murakami7, M. Casey8, M. Ji1, M. Lubetzky9, E. Tantisattamo10, O. Alomar1, A. Faravardeh11, C. Blosser12, A. Basu13, M. Molnar14, G. Gupta15, J. T. Adler16, D. Adey17, K. J. Woodside18, R. Parsons13, K. Lentine19

    1Wash U in St. Louis, Saint Louis, MO, 2Weill Cornell Med, New York, NY, 3Beth Israel, Boston, MA, 4U of Wisconsin, Madison, WI, 5Vanderbilt U, Nashville, TN, 6Northwell Health, Great neck, NY, 7Brigham and Women, Boston, MA, 8MUSC, Charleston, SC, 9Weill Cornell Medicine, New York, NY, 10UCI, Orange, CA, 11SHARP, San Diego, CA, 12U of Washington, Seattle, WA, 13Emory U, Atlanta, GA, 14U of Utah, Salt Lake City, UT, 15VCU, Richmond, VA, 16Surgery, Brigham and Women, Boston, MA, 17UCSF, San Francisco, CA, 18U of Michigan, Ann Arbor, MI, 19Saint Louis U, Saint Louis, MO

    *Purpose: Failing kidney allograft with subsequent return to dialysis is associated with high risk of morbidity and mortality. This project aimed to examine general nephrologist…
  • 2022 American Transplant Congress

    BK Polyomavirus Infection is Not Associated with a Meaningful Increase in Donor-Derived Cell-Free DNA

    J. Fisher1, K. Vieira1, R. Burke2, R. Gohh1, R. Rogers1

    1Warren Alpert Medical School of Brown University, Providence, RI, 2CareDx, Brisbane, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a non-invasive measure of early allograft injury that has been clinically validated as a surveillance tool to detect antibody…
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