Am J Transplant, Volume 22, Suppl 3 Archives - Page 50 of 190 - ATC Abstracts

2022 American Transplant Congress
Investigating RNA Interference-Mediated Inhibition of Liver Ischemia Reperfusion Injury During Liver Preservation
J. E. Buchwald¹, D. Echeverria², J. Sousa², N. McHugh², A. Khvorova², P. N. Martins³
¹RNA Therapeutics Institute, Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA, ²RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, ³Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA
*Purpose: Liver transplantation cures acute end-stage and chronic liver diseases, yet current strategies of organ preservation including static cold storage (SCS) and machine perfusion (MP)…
2022 American Transplant Congress
An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion Injury in a Murine Model
S. Duarte, A. Kobayashi, V. Boominathan, A. Kwiatkowski, J. Simonovich, A. Wanchoo, G. Hudalla, B. Keselowsky, A. Zarrinpar
University of Florida, Gainesville, FL
*Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor liver grafts. However, despite its…
2022 American Transplant Congress
Outcomes After Conversion to Belatacept in Pediatric Kidney Transplantation
C. Duneton, A. Maisin, E. Cheyssac, H. Dahdouh, V. Baudouin, J. Hogan
Pediatric Nephrology, Robert Debré Hospital, APHP, Paris, France
*Purpose: Belatacept (CTLA-Ig) is a selective co-stimulation blocker that is associated with reduced dnDSA, improved renal function, and prolonged allograft survival in adult transplant recipients…
2022 American Transplant Congress
Single Kidney Transplantation Using Pediatric Donor Kidneys: Satisfactory Outcomes but Specific Attentions Needed
M. Huang, W. Wu, X. Su, J. Li, C. Wu, H. Zhang, Q. Fu, J. Li, S. Wu, Y. Chen, Q. Zhang, L. Liu, C. Wang
The First Affiliated Hospital Of Sun Yat-sen University, Guangzhou, China
*Purpose: Utilization of pediatric donor in single kidney transplantation (SKT) are popular and can greatly expand the scarce donor pool, whereas potential risk factors remain…
2022 American Transplant Congress
Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Practice Patterns, Report from the Paramour “Pediatric Renal AMR Outcomes” Study
N. Hayde¹, K. Twombley², I. Ashoor³, R. Engen⁴, L. Harshman⁵, R. Zahr⁶, C. Peterson⁷, S. McEwen⁸, A. Jain⁹, R. Garro¹⁰, M. Kallash¹¹, A. Mansuri¹², D. Puliyanda¹³
¹Montefiore Medical Center, Bronx, NY, ²Medical University of South Carolina, Charleston, SC, ³LCMCHealth, New Orleans, LA, ⁴Pediatrics, University of Wisconsin Madison, Madison, WI, ⁵University of Iowa Children's Hospital, Iowa City, IA, ⁶Le Bonheur Children's Hospital, Nashville, TN, ⁷University of Utah, Salt Lake City, UT, ⁸University of Minnesota, Minneapolis, MN, ⁹Wayne State, Troy, MI, ¹⁰Emory Universtiy, Atlanta, GA, ¹¹The Ohio State, Columbus, OH, ¹²Augusta University Medical Center, Augusta, GA, ¹³Cedars-Sinai Med Ctr, West Hollywood, CA
*Purpose: There is insufficient data on children with AMR in the literature, and the optimal therapy for AMR is not well defined. We aim to…
2022 American Transplant Congress
Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion
L. James¹, M. D'Angelo¹, J. Carillo¹, J. C. Berger¹, D. E. Smith¹, N. Moazami¹, B. Lonze²
¹NYU Langone Health, New York, NY, ²NYU Langone Transplant Institute, New York, NY
*Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
2022 American Transplant Congress
Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient
A. Weissenbacher¹, S. Mathis², B. Cardini¹, C. Bogensperger¹, G. Putzer², L. Gasteiger², T. Resch¹, R. Oberhuber¹, D. Öfner¹, T. Hell³, J. Martini², S. Schneeberger¹
¹Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria, ²Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria, ³Department of Mathematics, Faculty of Mathematics, Computer Science and Physics, University of Innsbruck, Innsbruck, Austria
*Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…
2022 American Transplant Congress
Physician Preferences When Selecting Candidates for Marginal Quality Kidney Offers: A Discrete Choice Experiment
S. Mehrotra
Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL
*Purpose: This study assesses the tradeoffs that physicians make when accepting marginal-quality kidneys, and the extent to which recipient-specific factors influence the acceptability of these…
2022 American Transplant Congress
Physiological Age by Artificial Intelligence-Enhanced Electrograms as a Novel Biomarker of Mortality in Kidney Transplant Candidates
E. Lorenz, I. Zaniletti, B. Johnson, T. Petterson, W. Kremers, C. Schinstock, H. Amer, A. Cheville, N. LeBrasseur, A. Baez-Suarez, Z. Attia, F. Lopez-Jimenez, P. Friedman, C. Kennedy, A. Rule
Mayo Clinic, Rochester, MN
*Purpose: Assessing mortality risk prior to kidney transplantation is challenging. Age-Gap, which is the difference between physiological age determined by artificial intelligence-enhanced electrocardiograms (ECG) and…
2022 American Transplant Congress
Prevalence and Characteristics of Covid-19-Associated Pulmonary Diagnoses in Lung Transplant Patients in the United States
T. G. Mupfudze¹, A. R. Wilk¹, R. R. Goff¹, M. Valapour², J. Miller³, M. Budev², E. D. Lease⁴
¹Research Department, United Network for Organ Sharing, Richmond, VA, ²Respiratory Institute, Cleveland Clinic, Cleveland, OH, ³Scientific Registry of Transplant Recipients, Minneapolis, MN, ⁴Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA
*Purpose: Lung transplant may be a viable treatment option for select patients with non-recoverable COVID-19-associated acute respiratory distress syndrome (ARDS) and COVID-19-associated pulmonary fibrosis. This…