Am J Transplant, Volume 22, Suppl 3 Archives - Page 45 of 190 - ATC Abstracts

2022 American Transplant Congress
NecroX-7 Ameliorate FK506-Induced Nephrotoxicity in LLC-PK1 Cells (Pig Kidney Epithelial Cells)
H. J. Jang
Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea, Republic of
*Purpose: Tacrolimus (FK506) is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and…
2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
K. E. Karakasi¹, G. Katsanos², I. Karolos³, V. Tsioukas³, G. Tsoulfas⁴
¹University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, ²Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, ³School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, ⁴University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
2022 American Transplant Congress
The Unique Course of dd-cfDNA After Lung Transplant
D. Levine¹, C. Giner¹, C. Pham², R. Woodward³, A. Roux⁴
¹University of Texas Health System San Antonio, San Antonio, TX, ²CareDX, South San Francisco, CA, ³CareDx, South San Francisco, CA, ⁴Pneumology, Adult CF Center and Lung Transplantation Department, Foch Hospital, Suresnes, France
*Purpose: The time necessary for dd-cfDNA to reach baseline levels following transplantation has been reported in kidney, heart, and liver as 14-21 days. We explored…
2022 American Transplant Congress
CD31⁺ Extracellular Vesicles in Ex Vivo Lung Perfusion Are Associated with Unsuitability for Transplant
G. C. Madu¹, S. Moshkelgosha², A. Chruscinski³, A. Sage², M. Cypel², S. Keshavjee², S. Juvet²
¹Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada, ²University Health Network, Toronto, ON, Canada, ³Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada
*Purpose: Primary graft dysfunction (PGD) is an important cause of morbidity and mortality following lung transplantation and results in part from injuries sustained in the…
2022 American Transplant Congress
Dynamic Changes of Serum Soluble B Cell Activating Factor in Kidney Transplant with De Novo Donor Specific Antibody
S. Wu¹, X. Su¹, Y. Gao¹, Y. Wei¹, Q. Ye¹, M. Huang², Y. Chen¹, J. Wang¹, Q. Zhang³, Q. Fu¹, J. Li², H. Huang², B. Xu², H. Zhang¹, L. Liu², C. Wang²
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, ²The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, ³Charité - Universitätsmedizin Berlin, Berlin, Germany
*Purpose: De novo donor specific antibody (dnDSA) plays a crucial role in the development of antibody mediated rejection (ABMR) and is correlated to the worse…
2022 American Transplant Congress
Integrated Alcohol Use Disorder Clinic as a Strategy to Reduce Alcohol Relapse After Early Liver Transplantation in Patients with Alcohol Related Liver Disease
R. Z. Syed¹, C. Albers², N. Kemmer², V. Subramanian², C. Machado-Denis¹, K. Dhanireddy²
¹Hepatology and Liver Transplantation, Tampa General Hospital, Tampa, FL, ²Tampa General Hospital, Tampa, FL
*Purpose: In recent years, for patients with Alcohol related Liver Disease (ALD), there has been a trend towards early Liver Transplantation (LT) rather than waiting…
2022 American Transplant Congress
Critical Care of the Brain-Dead Recipient of a Pig-to-Human Renal Transplant
G. L. Piper¹, P. Sommer², J. M. Stern¹, B. Sullivan¹, E. Weldon¹, N. Lawson¹, B. Lonze¹, R. Dieter², G. Boulton¹, R. Montgomery¹
¹NYU Langone Transplant Institute, New York, NY, ²NYU Langone Health, New York, NY
*Purpose: The care of a brain dead (BD) patient undergoing xenotransplantation in a non-clinical environment poses unique challenges. Selection of an appropriate decedent, stabilization of…
2022 American Transplant Congress
Use of Ancestral Genetic SNP Phenotyping to Define Genotypic Ethnicity in Solid Organ Transplant Patients
P. Jindra, T. Tu, N. D'Silva, C. T. Stewart, J. Magana, N. Chitnis
Surgery, Baylor College of Medicine, Houston, TX
*Purpose: Transplantation research has mainly categorized ethnicity into four main groups African American, Caucasian, Hispanic, and Asian Pacific Islander. Our world has increased in admixure…
2022 American Transplant Congress
Detection of CMV Mediated Sub-Clinical Rejection by Urine Biomarkers
S. Ghosh¹, R. Sarwal¹, C. Mark¹, E. Reed², J. Shoji³, S. Bunnapradist², T. Sigdel³, M. Sarwal³
¹Nephrosant Inc, San Francisco, CA, ²UCLA, Los Angeles, CA, ³UCSF, San Francisco, CA
*Purpose: Research on early detection of Cytomegalovirus (CMV) mediated sub-clinical rejection (sAR) is in its nascence. This study explores the efficacy of urine-based biomarkers for…
2022 American Transplant Congress
Detection of Alloreactive CD8+ T Cell Responses and the Immunopeptidome That Elicits Their Activation
A. B. Morris, X. Zhang, E. V. Peek, A. Hadley, C. Larsen
Emory University, Atlanta, GA
*Purpose: T cell-mediated rejection results in graft dysfunction and contributes to premature failure. Due to the complexity of the TCR:pMHC interaction, prediction of alloreactive T…