ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Association of Chest CT Score During Acute COVID-19 Illness with Subsequent Lung Function Loss Among Lung Transplant Patients

    Q. M. Halverson, K. Batra, L. D. Mahan, M. Mohanka, A. C. Lawrence, J. Joerns, S. Bollineni, V. Kaza, I. L. Timofte, C. D. Kershaw, L. C. Terada, F. Torres, A. Banga

    University of Texas Southwestern, Dallas, TX

    *Purpose: Limited data exists on CT chest abnormalities during acute Coronavirus disease 2019 (COVID-19) infection and associated post-illness loss of lung function among lung transplant…
  • 2022 American Transplant Congress

    Single Cell And Spatial Transcriptomics Of Blood And Biopsies Reveals Enhanced Alloantigen Presenting Function And T-follicular Helper Cell (tfh) Expansion Early After Pediatric Liver Transplantation

    R. Sindhi1, C. Ashokkumar1, M. Ningappa1, D. Rajasundaram1, B. W. Higgs1, Q. Xu2, A. Zeevi2, M. Reyes-Mugica1

    1Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: We have previously reported enhanced B-cell presentation of donor antigen during early T-cell mediated liver transplant (LT) rejection.*Methods: To characterize B-cell related immunological mechanisms…
  • 2022 American Transplant Congress

    Direct Central Ambulatory Venoarterial Extracorporeal Membrane Oxygenation and Double Lung Transplantation without Graft Reduction with Extreme Mediastinal Shift

    A. Gorton1, S. Keshavamurthy2

    1Cardiothoracic Surgery, University of Kentucky, Lexington, KY, 2University of Kentucky, Lexington, KY

    *Purpose: Double Lung transplantation in the presence of extreme mediastinal shift can be technically challenging due to donor sizing and recipient factors.*Methods: We present the…
  • 2022 American Transplant Congress

    The Ontario Anatomic Kidney Score (OAKS) : Quantitative Macroscopic Assessment versus Histological Grading in Pre-transplant Evaluation of Donor Kidneys

    J. Mello Offerni1, D. Matty2, H. Abed3, P. Roshanov4, A. Sener1, P. Luke1

    1Urology, Western University, London, ON, Canada, 2Undergraduate Medical Education, Western University, Schulich School of Medicine & Dentistry, London, ON, Canada, 3Division of Urology, Department of Surgery, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada, 4Division of Nephrology, Department of Internal Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada

    *Purpose: Quantitative gross assessment of a kidney has not been used to influence the evaluation to utilize a kidney for transplantation. The Ontario Anatomic Kidney…
  • 2022 American Transplant Congress

    Validation of the iBox Surrogate End Point in CNI Free, Belatacept Treated Patients (BENEFIT & BENEFIT-EXT)

    G. Divard1, O. Aubert1, M. Raynaud1, F. Vincenti2, L. Rostaing3, A. Durbach4, C. Legendre1, R. Vadanici5, A. Loupy1, -. BENEFIT & BENEFIT-EXT Investigators6

    1Paris Transplant Group, INSERM, Paris, France, 2UCSF, San Francisco, CA, 3Grenoble, Grenoble, France, 4APHP, Paris, France, 5BMS, Rueil Malmaison, France, 6BMS, New York, NY

    *Purpose: The iBox is a prognostication system for long-term kidney allograft survival, developed with mostly patients under a CNI based immunosuppression. Patients treated with a…
  • 2022 American Transplant Congress

    DCD vs DBD Pancreas Transplant Outcome – A Comprehensive Registry Analysis

    A. C. Gruessner1, S. J. Saggi2, R. Gruessner1

    1SUNY Downstate Medical Center, Brooklyn, NY, 2Medicine, SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Pancreas transplantation offers long-term independence from insulin injections for patients with labile diabetes mellitus. After a decade of decline (2004-2015), the number of pancreas…
  • 2022 American Transplant Congress

    Final Flow and Resistance with Cold Pulsatile Perfusion Preservation Are Independent Risk Factors for Dialysis in the First Week Post-Transplant, Analysis of SRTR Data

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine if final flow or resistance on cold pulsatile perfusion preservation (CPPP) have independent predictive value for dialysis in the first week post-transplant.*Methods:…
  • 2022 American Transplant Congress

    VCA Waiting List and Transplant Trends and Challenges in the US

    J. Wainright1, W. Cherikh1, S. Booker1, D. Klassen2

    1Research, UNOS, Richmond, VA, 2Office of the CMO, UNOS, Richmond, VA

    *Purpose: VCA transplantation has grown and changed, encountering challenges such as scarce funding sources and the COVID-19 pandemic.*Methods: The OPTN cohort includes 105 candidates listed…
  • 2022 American Transplant Congress

    Crosstalk Between micro-RNAs, mRNAs, and Long Non-Coding RNAs in Human Hepatic Ischemia Reperfusion Injury

    C. Kuscu1, S. Naik1, C. Eymard2, A. Bajwa1, D. Maluf3, V. Mas3, J. Eason4, C. Kuscu1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 3Surgery, University of Maryland, Baltimore, MD, 4University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Present study utilizes multiple omics tools and clinical samples with a system biology approach characterizing mRNAs, long non-coding RNAs (lncRNAs) and small non-coding RNAs…
  • 2022 American Transplant Congress

    Donor App Increases Awareness and Overall Rates of Living Kidney Donation

    T. Shamaa1, I. Bajjoka1, H. Kandalaft1, R. Prashar2, M. Callaghan1, C. Crombez1, S. J. Serra1, M. Abouljoud1, J. Denny1

    1Transplant and Hepatobiliary Surgery, Henry Ford Transplant Institute, Detroit, MI, 2Transplant Nephrology, Henry Ford Transplant Institute, Detroit, MI

    *Purpose: The rate of living donor kidney transplants (LDKTs) performed has declined overall regardless of race. Studies show that web-based tools increase access to living…
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