Am J Transplant, Volume 22, Suppl 3 Archives - Page 44 of 190 - ATC Abstracts

2022 American Transplant Congress
P2X7R Inhibition Impairs In Vitro Training of Macrophages
H. H. Lancia¹, R. Sanchez², A. G. Lellouch¹, C. L. Cetrulo¹, J. Ochando³, G. Benichou⁴
¹Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, ²Icahn School of Medicine at Mount Sinai, New York, NY, ³Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, ⁴Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA
*Purpose: Macrophage training and ATP-mediated P2X7R signaling are unrelated key elements of the innate immune response associated with allotransplant rejection. In the present study, we…
2022 American Transplant Congress
Increased Plasminogen Activator Inhibitor-1 is Associated with Less Severe Clinical Bleeding After Reperfusion During Liver Transplantation
H. J. Braun, N. Ascher, G. Roll, J. Roberts, C. Niemann, M. Bokoch
University of California, San Francisco, San Francisco, CA
*Purpose: Severe bleeding following reperfusion in liver transplantation (LT) is often discrepant with available objective laboratory and thromboelastography data. This bleeding may be due to…
2022 American Transplant Congress
On the Circuit: Intra-Operative CRRT in Pediatric Liver Transplant Recipients with Acute Kidney Injury
E. Blanchette¹, M. Chandran², D. Yoeli³, M. Adams³, M. Bock¹
¹Pediatric Nephrology, University of Colorado, Aurora, CO, ²Transplant Pharmacy, University of North Carolina, Raleigh, NC, ³Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Acute renal failure is common in pediatric patients undergoing liver transplantation (LT), with an incidence of 17-55%. Fluid, metabolic and acid-base aberrancies are often…
2022 American Transplant Congress
Impact and Consequences of Recipient Gastroduodenal Artery (GDA) Ligation Prior to Hepatic Artery (HA) Anastomosis During Orthotopic Liver Transplantation (OLT)
A. Kumar, D. Gerber, C. Desai
Abdominal Transplant Surgery, UNC School of Medicine, Chapel Hill, NC
*Purpose: The recipient GDA is often ligated before the HA anastomosis during OLT either to gain mobility, length on recipient HA and with hypothesis that…
2022 American Transplant Congress
Evaluation of Voriconazole Dosing for Preventing Aspergillus in Lung Transplant Recipients
A. Chaplain¹, B. J. Pierce¹, C. Pham¹, A. Hutchins¹, W. L. Musick¹, D. T. Nguyen², E. A. Graviss², S. W. Yau³, J. G. Youssef³, A. Goodarzi³, H. J. Huang³
¹Pharmacy, Houston Methodist Hospital, Houston, TX, ²Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, ³Medicine, Houston Methodist Hospital, Houston, TX
*Purpose: We sought to evaluate the efficacy of voriconazole (VCZ) 200 mg twice a day (BID) for 3 months post lung transplant (LT) in preventing…
2022 American Transplant Congress
Depletion of Donor Macrophages Permits Post-Transplant Tolerance Induction
M. Dilts¹, A. Dangi², X. Luo³
¹Pathology, Duke University, Durham, NC, ²Medicine, Duke University, Durham, NC, ³Duke University School of Medicine, Durham, NC
*Purpose: Using donor splenocytes fixed with cross-linker ethylcarbodiimide (ECDI-SPs), our lab has induced tolerance in a variety of murine and non-human primate models when one…
2022 American Transplant Congress
Pretransplant Transcriptome Predicts 24-Month Kidney Function
E. Bardhi¹, K. Archer², D. Maluf¹, J. McDaniels¹, T. Rousselle¹, E. Akalin³, T. Mueller⁴, V. Mas¹
¹University of Maryland School of Medicine, Baltimore, MD, ²Ohio State University, Columbus, OH, ³Montefiore Medical Center, Bronx, NY, ⁴Universityspital Zurich, Zurich, Switzerland
*Purpose: With the development of novel prognostic tools derived from omics technologies, transplant medicine is entering the era of precision medicine, however, there are no…
2022 American Transplant Congress
Effects of Pre-Lung Transplantation Pulmonary Rehabilitation on Functional Capacity and Quality of Life
R. M. AlGhofaily
Physical Therapy, Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: Pulmonary rehabilitation (PR) prior lung transplantation (LT) has been effective in reducing post transplantation complications. However, few studies have examined the effect of pre-lung…
2022 American Transplant Congress
Variation Exists in Hospital Policies for Donation After Circulatory Death Within a Single Donor Service Area
R. Shabbir¹, S. Chebrolu², E. Vines³, C. Trahan³, P. Niles³, G. Testa¹, A. Wall¹
¹Baylor University Medical Center, Dallas, TX, ²Texas A&M University College of Medicine, Dallas, TX, ³Southwest Transplant Alliance, Dallas, TX
*Purpose: The Joint Commission mandates that all hospitals have a donation after circulatory death (DCD) policy. Previous studies have demonstrated variability in DCD policy elements.…
2022 American Transplant Congress
Increased Costs, Cold Ischemia Time, and Sharing Associated with Removing DSA and OPTN Region from Kidney Allocation: A Single-Center Analysis
R. Forbes¹, A. Dreher¹, E. Zavala², L. A. Hickman¹, L. Smith³, J. Lawson¹, D. Shaffer¹, B. P. Concepcion¹
¹Vanderbilt University Medical Center, Nashville, TN, ²Transplant Center, Vanderbilt University Medical Center, Nashville, TN, ³Vanderbilt Transplant Center, Nashville, TN
*Purpose: On March 15, 2021, Donation Service Area (DSA) and OPTN Region were removed from kidney allocation and replaced with a 250 nautical mile (NM)…