ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Induction Immunosuppression in ABO-Incompatible Liver Transplant Recipients

    S. Shaikh1, I. Hasan1, N. Kaur2

    1Keck Medicine of USC, Los Angeles, CA, 2Keck School of Medicine, Los Angeles, CA

    *Purpose: ABO-incompatible (ABO-i) liver transplantation (LT) has been associated with an increased risk of AMR, as well as poor patient and graft survival. With advances…
  • 2022 American Transplant Congress

    A New Algorithm Combining Donor Derived Cell-Free DNA Fraction and Quantity to Detect Kidney Transplant Rejection Using Molecular Diagnoses and Histology

    P. F. Halloran1, J. Reeve1, K. S. Madill-Thomsen1, N. Kaur2, E. Ahmed2, N. Al Haj Baddar2, Z. Demko2, N. Liang2, R. K. Swenerton2, B. G. Zimmermann2, P. Van Hummelen2, A. Prewett2, H. Tabriziani2, P. Gauthier2, P. R. Billings2

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2Natera, Inc., Austin, TX

    *Purpose: Donor derived cell-free DNA (dd-cfDNA) has been shown to be associated with allograft rejection, both histological and molecular (JASN, in press). Clinically available dd-cfDNA…
  • 2022 American Transplant Congress

    Experience with Covid-19 Infection and Vaccination in Combined Kidney/HSCT Recipients

    M. Gibson1, D. Belshe1, G. Gregory1, S. Tanna1, M. Ison1, S. Ildstad2, J. R. Leventhal1

    1Northwestern University, Chicago, IL, 2University of Louisville, Louisville, KY

    *Purpose: Kidney transplant(KTx) recipients are at increased risk of COVID-19 related complications. KTx pts who have undergone therapy to induce tolerance are a unique cohort…
  • 2022 American Transplant Congress

    Gm2a Regulates Memory Cd8+ T Cell Activation and Differentiation

    K. P. Tong1, K. M. Baecher2, C. R. Hartigan1, M. Ford3

    1Emory University Transplant Center, Emory University, Atlanta, GA, 2Department of Surgery, Emory University, Atlanta, GA, 3Emory University, Atlanta, GA

    *Purpose: In a clinical trial, patients who underwent kidney transplantation and were subsequently stable off tacrolimus immunosuppression exhibited increased Gm2a transcript in PBMC relative to…
  • 2022 American Transplant Congress

    When Pancreata Fly: Excellent Results from Long Distance Imported Pancreas Allografts

    N. Owen-Simon, G. Dube, P. Sandoval, L. Ratner, K. McCune

    Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY

    *Purpose: To address long waitlist times and increase pancreas transplantation in a competitive donor service area, our center has adopted a protocol for long distance…
  • 2022 American Transplant Congress

    Basiliximab Provides Similar Efficacy and Renal Recovery in Steroid-Minimal Liver Transplantation

    L. Bowman1, A. Webb1, Y. Alsalihi2, F. Fakhre3, R. Baliga4, V. Subramanian5, K. Robichaux3, S. Mohammed3, M. Gosselin6, J. Buggs5, A. Kumar7

    1Transplant Pharmacy, Tampa General Hospital, Tampa, FL, 2California Health Sciences University, Clovis, CA, 3University of South Florida, Tampa, FL, 4Florida Kidney Physicians, Tampa, FL, 5Transplant Surgery, Tampa General Hospital, Tampa, FL, 6University of Tampa, Tampa, FL, 7Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Due to nephrotoxic effects of tacrolimus, previous studies have evaluated the utility of basiliximab to delay or reduce tacrolimus for renal preservation in orthotopic…
  • 2022 American Transplant Congress

    Outcome of Living Donor Kidney Transplant and Deceased Donor Kidney Transplant: A Retrospective Cohort Study at National Kidney and Transplant Institute

    A. B. Burog, A. Parayno

    ORGAN TRANSPLANTATION AND VASCULAR SURGERY, National Kidney And Transplant Institute, Quezon City, Philippines

    *Purpose: To compare the graft and patient survival of living and deceased donor kidney transplant and identify the factors that affect graft survival.*Methods: Retrospective cohort…
  • 2022 American Transplant Congress

    Tacrolimus Metabolizer Heterogeneity within Caucasian Kidney Transplant (KT) Recipients

    J. Sanchez-Garcia1, N. Oliver1, D. Morris1, A. Raza1, L. Lindberg1, S. LeCorhick1, T. Srinivas2, S. Anand1

    1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA

    *Purpose: Weight-based tacrolimus (T) dosing is the standard in post-transplant KT. African-Americans and Caucasians differ in their metabolizer phenotype for T. However, two morphometrically similar…
  • 2022 American Transplant Congress

    Risk of Clostridioides Difficile Infection After Kidney Transplant

    C. Thomas1, B. Crowther2, K. Schwarz2, D. Chen1, Y. Shandaliy1, K. Johnson1, P. Klem2

    1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, 2Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Hospital System, Aurora, CO

    *Purpose: For patients undergoing kidney transplant, the risk of developing Clostridioides difficle infection (CDI) is reported to be 4.7%, likely due to risk factors such…
  • 2022 American Transplant Congress

    Muscle Damage from Hind Limb Transplantation Does Not Lead to Acute Kidney Injury

    D. Yoeli, Z. Wang, J. Huang, Y. Wang, B. Li, S. Jain, N. Nakra, K. Rampalski, A. Su, D. Mathes, K. Washington, E. Farkash, C. Huang, A. Jani

    University of Colorado Anschutz Medical, Aurora, CO

    *Purpose: The impact of muscle injury from vascularized composite allograft (VCA) transplantation ischemia-reperfusion injury on renal function is not well known. The aim of this…
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