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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Type 1 Innate Lymphoid Cells Alleviate Acute Liver Injury Following Transplantation via Interferon-γ Mediated Pathway

    H. Kojima, K. Kadono, H. Hirao, K. J. Dery, J. Kupiec-Weglinski, Y. Zhai

    Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: Innate lymphoid cells (ILCs), a heterogeneous population of non-B non-T lymphocytes, have been found in recent years to plays key regulatory roles in tissue…
  • 2022 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorder in Kidney and Simultaneous Pancreas and Kidney Transplant Recipients Predictors, and Patient and Allograft Outcomes

    M. A. Mohamed1, E. A. Yousif1, V. Manchala2, F. Aziz3, N. Garg4, S. Parajuli4, D. Mandelbrot5, B. Astor1

    1Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2Medicine-Transplant Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 3University of Wsiconsin, Madison, WI, 4University of Wisconsin, Madison, WI, 5UW Health, Madison, WI

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a devastating complication following kidney and pancreas transplantation. 12% of UNOS waitlisted candidates had previous transplant and 20% are…
  • 2022 American Transplant Congress

    Molecular ABO Typing: An Effective Tool for Resolving Deceased Donor Indeterminate ABO Types

    D. Tanglao1, S. S. Musa1, J. J. Chew1, L. Santiago2, K. Herron3, B. O'Neale3, N. A. Lemp1, S. O. Dionne4

    1Eurofins DPT, Los Angeles, CA, 2Eurofins DPT, Centennial, CO, 3Eurofins DPT, Centennial, CA, 4Eurofins DPT, denver, CO

    *Purpose: In order to evaluate molecular ABO typing as an alternative method of blood typing that may be employed when indeterminate serological typing results are…
  • 2022 American Transplant Congress

    Impact of Pretransplant Infectious Diseases Wellness Visit on Vaccine Uptake in Solid Organ Transplant Candidates

    J. Jarrah, Z. Hanna, J. Williams, J. McCorquodale, T. Párraga, S. Greenlee, O. Abreu Lanfranco, M. Ramesh, R. del Busto, G. Alangaden

    Transplant Infectious Diseases, Henry Ford Hospital, Detroit, MI

    *Purpose: Vaccination rates in solid organ transplant candidates (SOTc) remains suboptimal. We report the effect of a dedicated Infectious Disease Pre-transplant (IDPT) clinic visit on…
  • 2022 American Transplant Congress

    Impact of Induction Immunosuppression on Renal Recovery in Adult Liver Transplant Recipients – A Single Center Experience

    T. Zurick1, D. Bruno2, D. Kumar3, R. Winstead1, C. Song1, A. Brown1, S. Sterling1, I. Yakubu1

    1Pharmacy, VCU Health System, Richmond, VA, 2Transplant Surgery, VCU Health System, Richmond, VA, 3Transplant Nephrology, VCU Health System, Richmond, VA

    *Purpose: Renal dysfunction after liver transplantation (LT) is associated with increased morbidity and mortality. Early exposure to calcineurin inhibitors (CNI) is a risk factor for…
  • 2022 American Transplant Congress

    Impact of Glecaprevir/Pibrentasvir on Tacrolimus Concentration in Solid Organ Transplant Recipients with or without Triazole Antifungal Therapy

    D. Abraham1, A. Feist2, N. Law1, S. Aslam1, V. Nguyen1

    1University of California San Diego Health, San Diego, CA, 2University of California San Diego, San Diego, CA

    *Purpose: Provide guidance on tacrolimus (TAC) dose adjustments during glecaprevir/pibrentasvir (GLE/PIB) initiation and discontinuation in patients on triazole antifungals by comparing changes in TAC concentration-dose…
  • 2022 American Transplant Congress

    Three Month Antibody Durability and Kinetics in Sars-cov-2 Mrna Vaccinated Heart and Lung Transplant Recipients: Differences Above the Diaphragm

    J. L. Alejo1, J. Ruck1, T. Chiang1, A. Abedon1, J. Kim1, R. Avery1, A. Tobian1, M. Levan1, D. Warren1, A. Massie1, W. Werbel1, J. Garonzik-Wang2, D. Segev1

    1Johns Hopkins, Baltimore, MD, 2University of Wisconsin, Madison, WI

    *Purpose: Heart and lung transplant (HT/LT) recipients have impaired humoral responses to SARS-CoV-2 vaccination compared to other solid organ transplant recipients (SOTRs). The purpose of…
  • 2022 American Transplant Congress

    Normothermic Ex Vivo Perfusion of Discarded Human Pancreases: A Feasibility Study to Expand the Pancreas Donor Pool

    C. Parmentier, S. Ray, L. Mazilescu, M. Kawamura, Y. Noguchi, T. Goto, B. Arulratnam, S. Ganesh, M. Selzner, T. Reichman

    UHN - Toronto General Hospital, Toronto, ON, Canada

    *Purpose: Normothermic Ex Vivo Perfusion (NEVPP) model has been used in the clinical setting for Lung, heart, liver, and kidney. However, a system for human…
  • 2022 American Transplant Congress

    CD40 Expressed by FRC Regulates Lymph Node Structure and Function

    M. W. Shirkey1, L. Li1, R. Abdi2, J. S. Bromberg1

    1University of Maryland School of Medicine, Baltimore, MD, 2Transplant Research Center, Harvard Medical School, Boston, MA

    *Purpose: Fibroblastic reticular cells (FRC) support lymph node (LN) structure and can regulate T cell function through the CD40-CD40L pathway. Our previous work showed that…
  • 2022 American Transplant Congress

    An Additional Dose Of Viral Vector Covid-19 Vaccine And Mrna Covid-19 Vaccine In Kidney Transplant Recipients: A Randomized Controlled Trial

    J. Bruminhent1, C. Setthaudom2, P. Phornkittikorn3, P. Chaumdee3, S. Prasongtanakij4, S. Srisala4, K. Malathum1, S. Boongird5, A. Nongnuch5, M. Assanatham5, S. Kiertiburanakul1

    1Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 2Immunology Laboratory, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 3Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 4Office of Research, Academic Affairs and Innovation, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 5Division of Nephrology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

    *Purpose: An additional dose of the COVID-19 vaccine following a primary series is recommended for solid organ transplant recipients. However, a comparison of the immunogenicity…
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