2022 American Transplant Congress
Induction Immunosuppression in ABO-Incompatible Liver Transplant Recipients
1Keck Medicine of USC, Los Angeles, CA, 2Keck School of Medicine, Los Angeles, CA
*Purpose: ABO-incompatible (ABO-i) liver transplantation (LT) has been associated with an increased risk of AMR, as well as poor patient and graft survival. With advances…2022 American Transplant Congress
A New Algorithm Combining Donor Derived Cell-Free DNA Fraction and Quantity to Detect Kidney Transplant Rejection Using Molecular Diagnoses and Histology
1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2Natera, Inc., Austin, TX
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has been shown to be associated with allograft rejection, both histological and molecular (JASN, in press). Clinically available dd-cfDNA…2022 American Transplant Congress
Experience with Covid-19 Infection and Vaccination in Combined Kidney/HSCT Recipients
1Northwestern University, Chicago, IL, 2University of Louisville, Louisville, KY
*Purpose: Kidney transplant(KTx) recipients are at increased risk of COVID-19 related complications. KTx pts who have undergone therapy to induce tolerance are a unique cohort…2022 American Transplant Congress
Gm2a Regulates Memory Cd8+ T Cell Activation and Differentiation
*Purpose: In a clinical trial, patients who underwent kidney transplantation and were subsequently stable off tacrolimus immunosuppression exhibited increased Gm2a transcript in PBMC relative to…2022 American Transplant Congress
When Pancreata Fly: Excellent Results from Long Distance Imported Pancreas Allografts
Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY
*Purpose: To address long waitlist times and increase pancreas transplantation in a competitive donor service area, our center has adopted a protocol for long distance…2022 American Transplant Congress
Basiliximab Provides Similar Efficacy and Renal Recovery in Steroid-Minimal Liver Transplantation
*Purpose: Due to nephrotoxic effects of tacrolimus, previous studies have evaluated the utility of basiliximab to delay or reduce tacrolimus for renal preservation in orthotopic…2022 American Transplant Congress
Outcome of Living Donor Kidney Transplant and Deceased Donor Kidney Transplant: A Retrospective Cohort Study at National Kidney and Transplant Institute
*Purpose: To compare the graft and patient survival of living and deceased donor kidney transplant and identify the factors that affect graft survival.*Methods: Retrospective cohort…2022 American Transplant Congress
Tacrolimus Metabolizer Heterogeneity within Caucasian Kidney Transplant (KT) Recipients
1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA
*Purpose: Weight-based tacrolimus (T) dosing is the standard in post-transplant KT. African-Americans and Caucasians differ in their metabolizer phenotype for T. However, two morphometrically similar…2022 American Transplant Congress
Risk of Clostridioides Difficile Infection After Kidney Transplant
*Purpose: For patients undergoing kidney transplant, the risk of developing Clostridioides difficle infection (CDI) is reported to be 4.7%, likely due to risk factors such…2022 American Transplant Congress
Muscle Damage from Hind Limb Transplantation Does Not Lead to Acute Kidney Injury
University of Colorado Anschutz Medical, Aurora, CO
*Purpose: The impact of muscle injury from vascularized composite allograft (VCA) transplantation ischemia-reperfusion injury on renal function is not well known. The aim of this…
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