ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pseudomonas Related Pseudoaneurysm and Rupture of Transplant Renal Artery with Devastating Consequences – A Case Series

    S. Umapathy1, S. Nielsen1, A. Curtis1, A. Reyad1, J. Guiteau1, N. Umezurike1, S. Patel1, W. Miller2, L. Ostrosky-Zeichner2, M. Madhrira3, I. Memon3, B. Sankarapandian3, S. Allam3

    1Medical City Fort Worth, Fort Worth, TX, 2The University of Texas Health Science Center at Houston, Houston, TX, 3PPG Health, Fort Worth, TX

    *Purpose: Only few cases of infectious pseudoaneurysm of the transplant renal artery caused by Pseudomonas aeruginosa are reported in literature. Here we describe three such…
  • 2022 American Transplant Congress

    Use of Pronase to Identify HLA Crossmatch Antibody Interference

    N. Hendren1, C. Lacelle1, S. Carter1, J. L. Grodin1, E. Hardin2, M. Farr3, S. Garg1

    1UT Southwestern, Dallas, TX, 2University of Texas Southwestern Medical Center, Dallas, TX, 3University of Texas Southwestern, Dallas, TX

    *Purpose: Solid organ transplant centers should maintain vigilance that antibody therapies can impact HLA crossmatch results.*Methods: N/A*Results: A 46-year-old man with Mayo stage IV cardiac…
  • 2022 American Transplant Congress

    Early Experience Of 48-hour Normothermic Machine Perfusion In Human Kidneys Applying Urine Recirculation

    F. Messner1, S. Gasteiger1, M. Pühringer-Sturmayr1, A. Soleiman1, D. Öfner1, S. Schneeberger1, A. Weissenbacher2

    1Medical University of Innsbruck, Innsbruck, Austria, 2Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria

    *Purpose: Normothermic machine perfusion (NMP) of the kidney has been studied extensively during the past decade. Short-term kidney NMP has demonstrated promising results, however currently…
  • 2022 American Transplant Congress

    Donor Kidneys from Communities with Higher Deprivation Are Significantly More Likely to be Discarded

    J. Schold1, A. Huml1, E. Poggio1, E. Dewey1, R. Buchalter1, S. Husain2, S. Mohan2

    1Cleveland Clinic, Cleveland, OH, 2Columbia University, New York, NY

    *Purpose: The proportion of kidneys procured for the purpose of transplantation but ultimately discarded exceeds 20% in the US. Factors associated with deceased donor kidney…
  • 2022 American Transplant Congress

    A Comparison of Self-Reported Physical Function to In-Person Frailty Assessments for the Prediction of Rehospitalizations After Kidney Transplantation

    E. Lorenz1, C. Kennedy1, C. Schinstock1, A. Kukla1, D. Eton1, H. Wadei2, G. Mour3, P. Dean4, A. Rule1, N. LeBrasseur1, A. Cheville1

    1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Jacksonville, FL, 3Mayo Clinic, Scottsdale, AZ, 4Mayo Clinic Rochester, Rochester, MN

    *Purpose: Rehospitalizations are common after kidney transplantation (KT) and associated with increased cost, allograft failure, and death. Physical frailty as defined by Fried criteria has…
  • 2022 American Transplant Congress

    Regulatory Gene Pathways Are Upregulated in Heart Transplant Biopsies with Quilty Lesions

    Q. Cai, L. De Las Casas, J. Torrealba

    Pathology, UTSW Medical Ctr, Dallas, TX

    *Purpose: Quilty lesions (QL) are commonly sub-endocardial lymphoid aggregates found in biopsies from heart transplants. Their appearance and presence in the cardiac tissue is still…
  • 2022 American Transplant Congress

    Single-Cell RNA Sequencing Highlights the Role of Epithelial-Immune Dual Feature of Proximal Tubule Cells in BK Virus Nephropathy

    G. Huang, F. Yang, X. Chen, G. Zhao, H. Zhang, J. Luo, S. Yang, L. Zhou

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China

    *Purpose: BK virus nephropathy (BKVN) may cause renal allograft dysfunction and failure. However, a specific antiviral agent for BK virus does not exist. Increasing evidence…
  • 2022 American Transplant Congress

    Final Report of the Use of α-Lipoic Acid in Liver Transplantation to Prevent Ischemia Reperfusion Injury

    P. C. Casciato1, N. Ambrosi2, F. Caro2, L. Oliveira1, F. Zalazar1, A. Garmendia1, M. Bonifacio1, M. Padilla1, J. Paladini1, J. Di Menno1, J. Pekjol1, E. de Santibañes1, M. de Santibañes1, G. Adrian1, C. Incardona1, E. Chuluyan2

    1Hospital Italiano, Buenos Aires, Argentina, 2CEFYBO, Buenos Aires, Argentina

    *Purpose: The ischemia and reperfusion injury contributs to grafts deterioration and adverse post-transplant outcomes. The aim of the present study was to evaluate the safety…
  • 2022 American Transplant Congress

    Autoimmune Responses to DNA Topoisomerase I Exacerbate Renal Allograft Injury

    V. Gorbacheva, R. Fan, S. Miyairi, W. M. Baldwin, R. Fairchild, A. Valujskikh

    Inflammation and Immunity, Cleveland Clinic, Cleveland, OH

    *Purpose: Immune responses to self antigens develop following organ transplantation. Multiple studies describe correlations between pre-existing or de novo autoimmune responses and poor transplant outcome.…
  • 2022 American Transplant Congress

    A Single-Centre Study on the Diagnosis and Management of Transplant Ureteric Strictures: An 11 Year Experience

    W. G. Norton1, E. Aitken1, M. Clancy2, E. Murio1, K. Gillis1

    1Department of Renal Transplantation, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom, 2NHS Greater Glasgow and Clyde, Glasgow, United Kingdom

    *Purpose: The optimal management of transplant ureteric stricture is unclear. This study presents a single-centre's 11-year experience of the diagnosis and management of these cases.*Methods:…
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