ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Month 1 Donor Derived Cell Free DNA Levels Predict Future Kidney Transplant Rejection

    B. M. Kinsella1, K. Guo1, C. Rebello1, L. Zhao1, S. Park2, J. Friedewald1

    1Northwestern University, Chicago, IL, 2Transplant Nephrology, Northwestern University, Chicago, IL

    *Purpose: The purpose of this study was to determine if donor-derived cell-free DNA (dd-cfDNA) can be used one-month post-transplant to predict later allograft rejection.*Methods: Retrospective…
  • 2022 American Transplant Congress

    Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft

    E. S. Szuter1, T. Yokose1, M. T. Guinn1, J. Ge2, I. Rosales3, B. Kwon4, P. S. Russell1, A. Cuenca2, D. Kreisel5, P. Sage6, J. C. Madsen1, R. B. Colvin3, A. Alessandrini1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Boston Children's Hospital, Boston, MA, 3Department of Pathology, Massachusetts General Hospital, Boston, MA, 4Harvard College, Cambridge, MA, 5Department of Surgery, Washington University, St. Louis, MO, 6Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA

    *Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
  • 2022 American Transplant Congress

    The Role of Donor Sex in Females Undergoing Repeat Kidney Transplant: Does Prior Donor Sex Matter?

    S. Craig1, K. Tennankore2, A. J. Vinson2

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada

    *Purpose: Female recipients of male donor kidneys are at increased risk for graft failure compared with all other donor-recipient sex pairings. The presumed mechanism relates…
  • 2022 American Transplant Congress

    Timing of Hypotension Post Kidney Transplant Impacts the Risk of Subsequent Delayed Graft Function

    S. A. Morrison1, A. Thanamayooran2, K. Tennankore1, A. J. Vinson1

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada

    *Purpose: Hypotension is common post-kidney transplant and is associated with delayed graft function (DGF; a need for dialysis in the first week post-transplant) and prolonged…
  • 2022 American Transplant Congress

    De Novo DSA in the Setting of Stable Allograft Function is a Benign Finding

    R. J. Knight, E. A. Graviss, D. T. Nguyen, T. N. Eagar, S. G. Yi, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: We sought to determine the long-term outcome of renal allografts that developed de novo DSA (dnDSA) in the setting of stable renal function.*Methods: A…
  • 2022 American Transplant Congress

    De Novo Focal Segmental Glomerulosclerosis in the Kidney Allograft: Association with Alloimmunity Leading to Poor Outcome

    J. Leon1, J. Duong Van Huyen2, A. Abderrahmane1, D. Anglicheau1, C. Legendre1, M. Rabant2

    1KIDNEY TRANSPLANTATION, Necker Hospital, Paris, France, 2KIDNEY PATHOLOGY, Necker Hospital, Paris, France

    *Purpose: Focal Segmental Glomerulosclerosis (FSGS) can be found de novo (Dn) or as a recurrence in kidney allograft. While FSGS recurrence has been extensively described…
  • 2022 American Transplant Congress

    Poor Prognosis of Proliferative Glomerulonephritis with Monoclonal IgG Deposits in Renal Allografts: A Retrospective Multicenter Study from China

    Q. Wu1, D. Liang1, X. Ni1, T. Song2, X. Wu3, M. Zhang1, J. Chen1, D. Cheng1, W. Jiqiu1

    1National Clinical Research Center of Kidney Diseases, Jinling Hospital,Nanjing University Jinling School of Medicine, Nanjing, China, 2Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China, 3Department of Urology, Henan Provincial People's Hospital; Zhengzhou University People's Hospital, Zhengzhou, China

    *Purpose: To analyze the clinicopathological characteristics, treatment efficacy and prognosis of proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) in renal allografts from multi-centers in China.*Methods:…
  • 2022 American Transplant Congress

    Mortality and Cardiovascular Outcomes in Adult Non-Liver Solid Organ Transplant Patients with Non-Alcoholic Steatohepatitis

    N. Dutta1, N. Marka2, J. Lake1, N. Lim1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Clinical and Translational Sciences Institute, University of Minnesota, Minneapolis, MN

    *Purpose: Despite the increasing incidence of non-alcoholic steatohepatitis (NASH) worldwide, its impact on mortality or major adverse cardiovascular events (MACE) in non-liver solid organ transplant…
  • 2022 American Transplant Congress

    Characteristics and Outcomes of Anhepatic Patients Listed for Liver Retransplantation

    R. G. Kathawate1, T. Ibeabuchi2, P. Abt2, T. Bittermann2

    1University of Michigan, Ann Arbor, MI, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: The frequency and outcomes of anhepatic patients listed for transplantation in the United States has not been previously described. The United Network for Organ…
  • 2022 American Transplant Congress

    Are Autoimmune Conditions Disadvantaged Compared to Alcoholic Cirrhosis and Hepatocellular Carcinoma?

    S. S. Keeling

    Baylor College of Medicine, Houston, TX

    *Purpose: Orthotopic liver transplantation (OLT) is a lifesaving therapy for patients with irreversible liver damage caused by autoimmune liver diseases (ALD) including autoimmune hepatitis (AIH),…
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