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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Disparities in Liver Transplantation in Patients with HCC Diagnosis

    C. Warren1, A. Zarrinpar2

    1Surgery, University of Florida Shands Health, Gainesville, FL, 2Surgery, University of Florida Health Shands, Gainesville, FL

    *Purpose: Disparities in outcomes of hepatocellular carcinoma (HCC) have not been adequately studied, especially in the context of liver transplantation (LT). We sought to identify…
  • 2022 American Transplant Congress

    An Interventional Study Using Cell-Mediated Immunity to Guide Primary Prophylaxis for CMV Infection in Organ Transplant Recipients: A Multi-Center Study

    J. T. Solera1, C. Cervera2, S. Hosseini1, J. Gill3, S. Shalhoub4, J. Zaltzman5, N. Pinzon1, A. Humar1, D. Kumar1

    1UHN, Toronto, ON, Canada, 2UAlberta, Edmonton, AB, Canada, 3UBC, Vancouver, BC, Canada, 4LHSC, London, ON, Canada, 5StMH, Toronto, ON, Canada

    *Purpose: There are limited interventional studies using CMV cell-mediated immunity to guide the duration of antiviral prophylaxis. We aimed to use CMV CMI to guide…
  • 2022 American Transplant Congress

    Changes in Health Equity Under Liver Acuity Circles Allocation

    S. Noreen, J. Foutz, A. Henderson, D. Stewart

    United Network for Organ Sharing, Richmond, VA

    *Purpose: Acuity circles (AC) allocation was implemented on 2/4/2020 with a goal of removing DSA and region from liver allocation and sharing livers more broadly.…
  • 2022 American Transplant Congress

    Life Supporting Orthotopic Cardiac Xenotransplantation Using Multiple Human Gene Expressing Pigs in Non Human Primates

    A. K. Singh1, C. Goerlich1, T. Zhang1, I. Tatarov1, P. Odonkor1, E. Strauss1, B. Williams1, B. Lewis1, A. Hershfeld1, F. Sentz1, D. Ayares2, D. Kaczorowski1, B. Griffith1, M. Mohiuddin1

    1Department of Surgery, University of Maryland, Baltimore, MD, 2Revivicor Inc, Blacksburg, WV

    *Purpose: Cardiac xenotransplantation (CXTx) is proposed as an alternate treatment for end-stage cardiac failure patients. The prolonged survival of a heterotopic genetically engineered (GE) pig…
  • 2022 American Transplant Congress

    Healthcare Cost And Kidney Allocation In Liver Recipients With Kidney Disease

    Y. Lu1, X. Cheng2, S. Sanoff3, L. McElroy3

    1University of Michigan, Ann Arbor, MI, 2Stanford University, Palo Alto, CA, 3Duke University, Durham, NC

    *Purpose: End stage kidney disease (ESKD) in liver transplant (LT) candidates is associated with worse survival. We sought to identify the predictors of ESKD in…
  • 2022 American Transplant Congress

    HLA-DR/DQ Single Molecule Eplet Mismatch and Formation of De Novo Donor-Specific Anti-HLA Antibodies After Kidney Transplantation in Children

    V. K. Sigurjonsdottir1, K. Piburn1, P. C. Grimm1, B. M. Zhang2

    1Division of Nephrology, Department of Pediatrics, Stanford University, Palo Alto, CA, 2Histocompatibility and Immunogenetics Laboratory, Stanford Blood Center, Palo Alto, CA

    *Purpose: The advances in HLA typing methods and elucidation of three-dimensional molecular structures of HLA antigens in recent years have allowed analysis of donor/recipient HLA…
  • 2022 American Transplant Congress

    Transjugular Intrahepatic Portosystemic Shunt Placement is Associated with Increased All-Cause and Cardiac Mortality in Those Undergoing Liver Transplant for Nonalcoholic Steatohepatitis

    D. U. Lee1, J. Han2, J. Kwon2, K. Chang2, G. Fan2, K. Lee1, N. Urrunaga3, C. Bhati1, D. Maluf3, K. Shetty3

    1Department of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, 2Tufts Medical Center, Boston, MA, 3University of Maryland, Baltimore, MD

    *Purpose: Since the effect of transjugular intrahepatic portosystemic shunt (TIPS) on post LT outcomes is not well understood, we undertook this analysis of a large…
  • 2022 American Transplant Congress

    Public Acceptance of Living Donor Liver Transplant for Colorectal Liver Metastases: A National Survey

    E. Pope-Collins, M. Nickels, K. Dokus, J. Martens, E. Keller, R. Hernandez-Alejandro, B. Al-Judaibi

    University of Rochester, Rochester, NY

    *Purpose: Recent advancements in cancer treatment and post-transplant management have allowed for a wider population of living donor transplant candidates. We employed a national survey…
  • 2022 American Transplant Congress

    Reduction of Discharge Opioid Prescriptions After Kidney Transplantation: A Quality Improvement Project

    A. W. Rogers, E. Rizk, J. T. Swan, S. G. Yi, M. Hobeika, R. R. McMillan, J. C. Krisl, H. Podder, A. O. Gaber, R. J. Knight

    Houston Methodist Hospital, Houston, TX

    *Purpose: Opioid use after kidney transplant has been linked to poorer outcomes, and unused prescriptions can lead to potential misuse. Historical prescribing practice at our…
  • 2022 American Transplant Congress

    MTOR Inhibition Acts Directly on Endothelial Cells to Induce Contact-Independent Immune-Modulation of Allo-Specific T Cell Activation

    H. Xu, L. Wang, V. A. Bendersky, Q. Gao, Q. Li, A. D. Kirk, H. Xu

    Duke University School of Medicine, Durham, NC

    *Purpose: Endothelial cells (ECs) form a barrier between vascularized organ allografts and host immunity and are known to provoke alloimmune responses. The mTOR inhibitor rapamycin…
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