Am J Transplant, Volume 22, Suppl 3 Archives - Page 36 of 190 - ATC Abstracts

2022 American Transplant Congress
Of the Individual Components of a Modified Freid Frailty Score, Pre-Transplant Walk Time and Grip Strength Are the Strongest Predictors of Post Kidney Transplant Outcomes
S. Parajuli, F. Aziz, H. L. Lorden, K. A. O'Toole, R. E. Wallschlaeger, I. C. Breyer, B. Dodin, J. Goronzik Wang, D. A. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Frailty assessment has become common during evaluation for kidney transplantation; however, a variety of different tools are used for frailty assessment. The Freid frailty…
2022 American Transplant Congress
Impact of Donor and Recipient Characteristics on Early Post-Transplant Donor-Derived Cell-Free DNA (dd-cfDNA) Scores
A. Alam¹, J. Zeng², J. Teuteberg³, S. Hall¹
¹Baylor University Medical Center, Dallas, TX, ²CareDx, Brisbane, CA, ³Stanford University, Stanford, CA
*Purpose: Dd-cfDNA (AlloSure, CareDx; Brisbane, CA) has been demonstrated to detect allograft injury after heart transplantation in a large and diverse patient cohort in the…
2022 American Transplant Congress
The Molecular Landscape of Bk Polyomavirus Infection in Kidney Transplant Recipients at Single Cell Resolution
P. J. McCown, E. Farkash, F. Alakwaa, F. Eichinger, R. Menon, E. Otto, C. C. Berthier, K. J. Woodside, S. Norman, M. Kretzler, A. Naik
University of Michigan, Ann Arbor, MI
*Purpose: BK polyomavirus has devastating consequences in patients with kidney transplants. While in vitro studies in primary epithelial cell lines, and bulk transcriptomic studies in…
2022 American Transplant Congress
Comparative Analysis of Liver Organ Offers Pre- and Post- Acuity Circle Policy Change in the US
V. Reddy¹, R. Ruiz², H. Fernandez³, J. Bayer³, E. Martinez³, A. Gupta³, G. McKenna⁴, N. Onaca³, S. Lee³, T. Ma³, G. Testa³, A. Wall³
¹Baylor Scott and White Research Institute, Allen, TX, ²Baylor University Medical Center, Fort Worth, TX, ³Baylor University Medical Center, Dallas, TX, ⁴Baylor Simmons Transplant Inst, Dallas, TX
*Purpose: With the intended goal of reducing geographic inequities, the United Network for Organ Sharing (UNOS) and Organ Procurement and Transplantation Network (OPTN) transitioned to…
2022 American Transplant Congress
The Roles of Intrarenal B Cells in Regulating Antibody Mediated Rejection After Kidney Transplantation
H. Zhang¹, C. Cavazzoni¹, E. Bechu¹, B. Hanson¹, M. A. Podestà¹, D. Kreisel², A. Alessandrini³, P. Sage¹
¹Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ²Department of Surgery, Washington University in St Louis, St. Louis, MO, ³Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard, Boston, MA
*Purpose: Alloimmune rejection after kidney transplantation is associated with substantial infiltration of immune cells such as T and B cells in transplanted grafts. However, the…
2022 American Transplant Congress
Pre-Transplant Ex-Vivo Analysis of Kidney Vasculature and Perfusion Using Contrast Computed Tomography
A. Feizi¹, J. R. DiRito¹, M. Harris¹, J. C. Stendahl¹, S. Spindler¹, C. M. Edwards¹, T. Lysyy¹, S. Lee¹, N. Boutagy¹, A. Fehér¹, P. Yoo¹, S. A. Hosgood², D. C. Mulligan¹, M. L. Nicholson², A. J. Sinusas¹, D. J. Haakinson¹, G. T. Tietjen¹
¹Yale School of Medicine, New Haven, CT, ²University of Cambridge, Cambridge, United Kingdom
*Purpose: Ex-vivo normothermic perfusion (NMP) has been developed with the goal of improving viability of the thousands of donated organs that are declined for transplant…
2022 American Transplant Congress
Racial Disparities in Preemptive Kidney Transplantation Beyond Listing Estimated Glomerular Filtration Rate
K. L. King¹, S. Husain², S. Mohan²
¹Medicine - Nephrology, Columbia University Medical Center, New York, NY, ²Columbia University Medical Center, New York, NY
*Purpose: Given recent attention on the impact of the race coefficient in equations for estimated glomerular filtration rate (eGFR) on racial disparities in kidney transplantation,…
2022 American Transplant Congress
Allocation Based on Acuity Circles: Effects on Pediatric Liver Allocation
M. H. Kim, K. Sasaki, A. Gallo, T. Pham, M. L. Melcher, S. Busque, C. Esquivel, C. Bonham
Stanford University, Stanford, CA
*Purpose: In February, 2020, UNOS implemented a new liver allocation system incorporating a combination of acuity based on MELD/PELD score and distance from the donor…
2022 American Transplant Congress
Surveillance with Allosure for Allograft Rejection and Infection in Lung Transplant
M. M. Botros¹, N. Sulejmani², B. F. Reader³, B. C. Keller¹
¹Pulmonary, Critical Care & Sleep Medicine, The Ohio State University, Columbus, OH, ²Medical Affairs, CareDx, South San Francisco, CA, ³Division of Transplant Surgery, The Ohio State University, Columbus, OH
*Purpose: Measurement of plasma donor-derived cell-free DNA (dd-cfDNA; AlloSure, CareDx) has been shown to be a useful non-invasive diagnostic test for injury and infection after…
2022 American Transplant Congress
Infectious Disease Testing Among US Deceased Organ Donors
A. Mezochow¹, T. Bittermann¹, E. Blumberg¹, R. Hasz², J. Anesi¹
¹Hospital of the University of Pennsylvania, Philadelphia, PA, ²Gift of Life Donor Program, Philadelphia, PA
*Purpose: Donor-derived infections are associated with significant morbidity in solid organ transplant recipients. To reduce the risk of donor-derived infections, the United Network for Organ…