ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Tacrolimus Exposure Estimation in Stable Kidney Transplant Recipients Using Maximum A Posteriori Bayesian Approach

    T. Nguyen1, N. M. Smith1, K. Attwood2, B. Murray3, K. Tornatore-Morse1

    1University at Buffalo School of Pharmacy and Pharmaceutical Sciences, Buffalo, NY, 2School of Public Health; University at Buffalo, Buffalo, NY, 3Erie County Medical Center; School of Medicine/UB, Buffalo, NY

    *Purpose: Tacrolimus exhibits interpatient pharmacokinetic variability that impacts clinical responses and requires routine trough therapeutic drug monitoring. Tacrolimus troughs do not consistently predict area under…
  • 2022 American Transplant Congress

    Augmented Reality in Hand-Assisted Retroperitoneal Donor Nephrectomy – Procedure Step Adjusted Evaluation for the Surgeons’ Benefits

    R. Wahba1, L. Krames2, J. Hogervorst3, R. R. Datta1, M. N. Thomas1, P. Suppa3, D. L. Stippel1

    1Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Köln, Germany, 2Karlsruhe Institute of Technology, Institute of Biomedical Engineering (IBT), Karlsruhe, Germany, 3Olympus Surgical Technologies Europe, Hamburg, Germany

    *Purpose: To identify procedure steps where a patient-specific CT-reconstructed virtual 3D model of the kidney displayed on the screen can support the surgeon while performing…
  • 2022 American Transplant Congress

    Variable Course of Hepatitis A Virus Infection in Solid Organ Transplant Recipients

    A. Vostal1, J. Husson2, A. Shishido1, N. Jakhete3, E. Moore4, X. Wen5, A. Amoroso2, R. Meier6, E. Wilson2, K. K. Saharia2

    1Div. of Infectious Diseases, Univ. of Maryland Medical Center, Baltimore, MD, 2Div. of Infectious Diseases, Univ. of Maryland School of Medicine and Institute of Human Virology, Baltimore, MD, 3Div. of Hepatology, Univ. of Maryland School of Medicine, Baltimore, MD, 4Dept of Surgery, Brooklyn Hospital Center, Brooklyn, NY, 5Dept. of Surgery, Univ. of Florida, Gainesville, FL, 6Dept. of Surgery, Univ. of Maryland School of Medicine, Baltimore, MD

    *Purpose: Although Hepatitis A virus (HAV) infection is typically a self-limited disease in immunocompetent individuals, the natural history and viral kinetics of HAV in solid…
  • 2022 American Transplant Congress

    One Nuclei at a Time: Decoding Kidney Allograft Fibrosis by Single Nuclei RNA-Sequencing

    J. McDaniels1, A. Shetty1, C. Kuscu2, C. Kuscu2, E. Bhardi1, T. Rousselle1, C. Drachenberg3, M. Talwar4, J. Eason5, T. Muthukumar6, D. Maluf1, V. Mas1

    1University of Maryland, Baltimore, Baltimore, MD, 2University of Tennessee Health Science Center, Memphis, TN, 3University of Maryland, Baltimore, MD, 4UTHSC, memphis, TN, 5University of Tennessee/Methodist Transplant Institute, Memphis, TN, 6Weill Cornell Medicine, New York, NY

    *Purpose: The biological mechanisms underpinning late graft loss due to chronic allograft dysfunction remain unknown. Single nuclei RNA-sequencing (snRNAseq) of healthy and fibrotic kidney grafts…
  • 2022 American Transplant Congress

    Financial Impact of Adult Kidney Transplant MS-DRGs 650, 651 and 652 in U.S. Transplant Hospitals

    E. Zavala1, J. Rogers2, H. Buschmann1, S. Rath1, S. Karp1

    1VUMC, Nashville, TN, 2Transplant Management Group, San Diego, CA

    *Purpose: The Medicare Hospital Inpatient Prospective Payment System (IPPS) permits each inpatient admission to be categorized into a diagnosis-related group (DRG). DRGs can be further…
  • 2022 American Transplant Congress

    Preemptive Therapy in Cytomegalovirus (CMV) Seropositive Donor to Seronegative Recipient Liver Transplants

    J. Revollo, E. Aldag, K. Cooper, B. Noell, V. Casingal, K. Gajurel

    Transplant, Atrium Health's Carolinas Medical Center, Charlotte, NC

    *Purpose: To evaluate if a preemptive therapy strategy can prevent CMV disease and induce CMV seroconversion.*Methods: Observational data collection for CMV D+/R- adult liver transplant…
  • 2022 American Transplant Congress

    Delayed Graft Function in Kidney Transplant Recipients is Associated with an Increased Risk f Post-Transplant Infections

    V. Manchala, B. Muth, E. Yousif, J. Turk, J. Blazel, M. Bloom, N. Garg, F. Aziz, M. Mohamed, A. Djamali, D. Mandelbrot, B. Astor, S. Parajuli

    UWSMPH, Madison, WI

    *Purpose: Delayed graft function (DGF) is a known complication among kidney transplant recipients (KTRs) and is associated with decreased graft survival, increased rejection, and increased…
  • 2022 American Transplant Congress

    Outcome of Donor Derived and Community Acquired West Nile Infections in Kidney Transplant Recipients

    R. K. Thimmisetty1, G. Larrieux2, S. Wilson2, F. Barrantes1, S. Kundeling1, J. Kumar1

    1Renal Medicine Associates, Albuquerque, NM, 2Presbyterian Health Services, Albuquerque, NM

    *Purpose: Donor derived West Nile Virus(WNV) Infections can occur but rare. We are presenting four cases that were seen at our transplant center*Methods: Case 1:…
  • 2022 American Transplant Congress

    Use of Kidneys from Hepatitis C Nat Positive Donors for Uninfected Recipients: Early Results from a Rural Appalachian Kidney Transplant Program

    B. Gillis1, F. Afridi1, R. Lopez1, V. Chaudhary1, D. Kannabhiran1, C. Fagella1, R. Zomak1, K. Meyer1, M. Thornberg1, L. Biondi2

    1Department of Surgery, West Virginia University, Morgantown, WV, 2Department of Surgery, West Virginia University, Morgantown, WV, WV

    *Purpose: Increasing mismatch between kidneys available for transplant and the number of patients on the transplant wait list has led to research into novel sources…
  • 2022 American Transplant Congress

    Evaluation of GLP-1 Receptor Agonist Use in the Solid Organ Transplant Population

    S. E. Lawrence, M. R. Norvell, K. Schwarz, B. Crowther, P. Klem

    Pharmacy, University of Colorado Hospital, Aurora, CO

    *Purpose: The purpose of this study was to evaluate the utilization of and identify opportunities to optimize the use of glucagon-like peptide-1 receptor agonist (GLP-1…
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