ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Performance of Updated Estimated Glomerular Filtration Rate Equations in Black Living Kidney Donor Candidates

    J. Augustine, A. Liaqat, S. Arrigain, J. Schold, E. Poggio

    Cleveland Clinic, Cleveland, OH

    *Purpose: New estimated glomerular filtration rate (eGFR) equations using serum creatinine (Cr) and/or cystatin C (CysC) have been derived to eliminate adjustment by perceived Black…
  • 2022 American Transplant Congress

    Single Center Experience of Utilizing Genetic Testing (Renasight) in the Kidney Transplant Setting

    Y. A. Qazi, W. Mon, M. Renzu, C. Choi, A. Qazi, M. Smogorzewski

    KECK Medical Center at USC, Los Angeles, CA

    *Purpose: Advances in next generation gene sequencing has made evaluation of genes associated with kidney easily accessible in the clinical settings. Renasight testing analyzes over…
  • 2022 American Transplant Congress

    Outcomes Following Liver Re-Transplantation for Delayed Graft Loss in Recipients of Donation After Circulatory Death Allografts in the United States

    S. Kumar1, S. Lin2, J. D. Schold3

    1Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 2Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Center for Populations Health Research, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Donation after circulatory death (DCD) liver transplant (LT) recipients have a higher likelihood of delayed graft loss due to Ischemic cholangiopathy (IC). Limited data…
  • 2022 American Transplant Congress

    A Machine Learning Approach to Estimating Anticipated Waiting Time and Survival Benefit in Older Kidney Transplant Candidates

    D. M. Vock1, E. S. Helgeson2, A. J. Matas2

    1University of Minnesota, Minneapolis, MN, 2U MN, Mpls, MN

    *Purpose: Older kidney transplant (ktx) recipients face worse post-transplant survival due to increasing age and more comorbidities. Simultaneously, older ktx candidates are more likely to…
  • 2022 American Transplant Congress

    Decision-Making Among HCV-Negative Transplant Candidates Offered Organs from Donors with HCV Infection

    E. Schnellinger1, E. Saine1, M. Liu1, J. Diamond1, M. Crespo1, S. Prenner1, V. Potluri1, C. Bermudez1, H. Mentch1, M. Moore2, B. Besharatian1, D. Goldberg3, F. Barg1, P. Reese1

    1University of Pennsylvania, Philadelphia, PA, 2University of London, London, United Kingdom, 3University of Miami, Miami, FL

    *Purpose: Historically, many organs from deceased donors with hepatitis C virus (HCV) infection were discarded due to stigma and challenges in treating HCV after transplant.…
  • 2022 American Transplant Congress

    TEMRA CD8 T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2x4 Receptor-Dependent Proinflammatory and Migratory Responses

    G. Tilly1, T. Doan-Ngoc1, O. Bonizec1, C. Masset2, R. Danger3, P. Guérif1, S. Bruneau1, J. Harb1, M. Giral1, C. Pecqueur4, S. Brouard1, N. Degauque1

    1Nantes Université, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France, 2University Hospital of Nantes, Nantes, France, 3CRTI- INSERM UMR 1064, Nantes, France, 4Nantes Université, Univ Angers, INSERM, CNRS, CRCINA, F-44000 Nantes, Nantes, France

    *Purpose: Whereas the role of effector memory and TEMRA CD8 in allotransplantation has been clearly evidenced and particularly the direct correlation between intragraft infiltrating CD8…
  • 2022 American Transplant Congress

    Why Females Have Weaker Tregs Than Males: Inhibitory Effects of Estrogen Receptor Signaling on Foxp3+ Treg Cell Suppressive Function

    L. M. Christensen1, T. Akimova1, G. Ge2, R. Han1, L. Wang3, C. O'Brien2, M. Levine2, W. W. Hancock3

    1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Childrens Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Estrogen signaling is thought to play a role in nearly every cell type, but the biological significance of estrogen signaling via estrogen receptors in…
  • 2022 American Transplant Congress

    Utilizing Microporous Annealed Particle (MAP) Gel as an Immunomodulatory Carrier for Islet Delivery

    M. Ma1, P. Chhabra1, C. Roosa2, D. R. Griffin2, K. L. Brayman1

    1Department of Surgery, University of Virginia Health System, Charlottesville, VA, 2Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA

    *Purpose: To investigate if coating with MAP gel improves dissociated or whole islet transplantation outcome.*Background: MAP gel platform technology is composed of hydrogel microspheres that…
  • 2022 American Transplant Congress

    Allogenic Cardiac Progenitor Cells Transplantation with Immune Suppressant Cyclosporine a Recovers Myocardial Infarction in Rodent Model

    M. Gunasekaran, R. Mishra, S. Sharma, P. Saha, L. Chen, S. Guru, A. Stefanowicz, A. Bilewska, S. Zarinebaf, G. Zhi-Dong, S. Kaushal

    Pediatrics, Lurie Childrens Hospital, Chicago, IL

    *Purpose: Cardiac progenitor cells (CPCs) are well-characterized stem cell type shown to potentiate cardiac regeneration in myocardial infarct (MI) model. However, auto and allo immune…
  • 2022 American Transplant Congress

    Cd47 Expression on Transplanted Human Neonatal Mesenchymal Stem Cells Inhibits Phagocytosis in Rat Myocardial Infarction Model

    M. Gunasekaran, R. Mishra, S. Sharma, P. Saha, L. Chen, S. Guru, A. Stefanowicz, A. Bilewska, S. Zarinebaf, G. Zhi-Dong, S. Kaushal

    Lurie Childrens Hospital, Chicago, IL

    *Purpose: Immune rejection of transplanted stem/progenitor cells is a major stumbling block in designing effective therapy for myocardial infarction (MI). Human neonatal mesenchymal stem cells…
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