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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    The Prevalence and Morbidity Associated with BK Virus in Heart Transplant Recipients

    A. Nguyen1, Z. Li2, N. F. Rasheed2, J. Cruz2, M. Fei3, G. Kim1, S. Pinney1, N. Uriel4

    1University of Chicago Medicine, Chicago, IL, 2University of Chicago, Chicago, IL, 3CareDx, Brisbane, CA, 4New York Presbyterian, Columbia University Irving Medical Center, New York, NY

    *Purpose: BK polyomavirus (BKV) is a quiescent polyomavirus that is present in approximately 80% of the population and can reactivate in immunocompromised patients and impair…
  • 2022 American Transplant Congress

    Co-stimulation Patways Pd-1 (the Programmed Death 1) And Icos (the Inducible T Cell Co-stimulator) In Peripheral Mononuclear Cells Mesured By Flow Cytometry As A Possible Tool In The Follow-up And Diagnosis Of Kidney Transplant Rejection.

    M. A. Carmona-Escamilla

    Posgrado de Ciencias médicas, Universidad Nacional Autonoma de México, CDMX, Mexico

    *Purpose: Currently, the follow-up of KT in the clinic remains the creatinine levels, this is a highly specific, however, without sensitivity to determine diagnosis of…
  • 2022 American Transplant Congress

    Early Kidney Transplantation Irrespective of Donor Profile Offers Survival Benefit in Recipients Older Than 70 Years

    A. Mujkanovic1, T. Jarmi2, C. B. Taner1, K. P. Croome1, S. A. Mao1

    1Transplant Surgery, Mayo Clinic, Jacksonville, FL, 2Transplant Medicine, Mayo Clinic, Jacksonville, FL

    *Purpose: Donor and recipient pre-transplant risk factors are known to influence post-transplant recipient survival. This study’s purpose was to identify the most important donor and…
  • 2022 American Transplant Congress

    Of the Individual Components of a Modified Freid Frailty Score, Pre-Transplant Walk Time and Grip Strength Are the Strongest Predictors of Post Kidney Transplant Outcomes

    S. Parajuli, F. Aziz, H. L. Lorden, K. A. O'Toole, R. E. Wallschlaeger, I. C. Breyer, B. Dodin, J. Goronzik Wang, D. A. Mandelbrot

    University of Wisconsin, Madison, WI

    *Purpose: Frailty assessment has become common during evaluation for kidney transplantation; however, a variety of different tools are used for frailty assessment. The Freid frailty…
  • 2022 American Transplant Congress

    Impact of Donor and Recipient Characteristics on Early Post-Transplant Donor-Derived Cell-Free DNA (dd-cfDNA) Scores

    A. Alam1, J. Zeng2, J. Teuteberg3, S. Hall1

    1Baylor University Medical Center, Dallas, TX, 2CareDx, Brisbane, CA, 3Stanford University, Stanford, CA

    *Purpose: Dd-cfDNA (AlloSure, CareDx; Brisbane, CA) has been demonstrated to detect allograft injury after heart transplantation in a large and diverse patient cohort in the…
  • 2022 American Transplant Congress

    The Molecular Landscape of Bk Polyomavirus Infection in Kidney Transplant Recipients at Single Cell Resolution

    P. J. McCown, E. Farkash, F. Alakwaa, F. Eichinger, R. Menon, E. Otto, C. C. Berthier, K. J. Woodside, S. Norman, M. Kretzler, A. Naik

    University of Michigan, Ann Arbor, MI

    *Purpose: BK polyomavirus has devastating consequences in patients with kidney transplants. While in vitro studies in primary epithelial cell lines, and bulk transcriptomic studies in…
  • 2022 American Transplant Congress

    Comparative Analysis of Liver Organ Offers Pre- and Post- Acuity Circle Policy Change in the US

    V. Reddy1, R. Ruiz2, H. Fernandez3, J. Bayer3, E. Martinez3, A. Gupta3, G. McKenna4, N. Onaca3, S. Lee3, T. Ma3, G. Testa3, A. Wall3

    1Baylor Scott and White Research Institute, Allen, TX, 2Baylor University Medical Center, Fort Worth, TX, 3Baylor University Medical Center, Dallas, TX, 4Baylor Simmons Transplant Inst, Dallas, TX

    *Purpose: With the intended goal of reducing geographic inequities, the United Network for Organ Sharing (UNOS) and Organ Procurement and Transplantation Network (OPTN) transitioned to…
  • 2022 American Transplant Congress

    The Roles of Intrarenal B Cells in Regulating Antibody Mediated Rejection After Kidney Transplantation

    H. Zhang1, C. Cavazzoni1, E. Bechu1, B. Hanson1, M. A. Podestà1, D. Kreisel2, A. Alessandrini3, P. Sage1

    1Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 2Department of Surgery, Washington University in St Louis, St. Louis, MO, 3Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard, Boston, MA

    *Purpose: Alloimmune rejection after kidney transplantation is associated with substantial infiltration of immune cells such as T and B cells in transplanted grafts. However, the…
  • 2022 American Transplant Congress

    Pre-Transplant Ex-Vivo Analysis of Kidney Vasculature and Perfusion Using Contrast Computed Tomography

    A. Feizi1, J. R. DiRito1, M. Harris1, J. C. Stendahl1, S. Spindler1, C. M. Edwards1, T. Lysyy1, S. Lee1, N. Boutagy1, A. Fehér1, P. Yoo1, S. A. Hosgood2, D. C. Mulligan1, M. L. Nicholson2, A. J. Sinusas1, D. J. Haakinson1, G. T. Tietjen1

    1Yale School of Medicine, New Haven, CT, 2University of Cambridge, Cambridge, United Kingdom

    *Purpose: Ex-vivo normothermic perfusion (NMP) has been developed with the goal of improving viability of the thousands of donated organs that are declined for transplant…
  • 2022 American Transplant Congress

    Racial Disparities in Preemptive Kidney Transplantation Beyond Listing Estimated Glomerular Filtration Rate

    K. L. King1, S. Husain2, S. Mohan2

    1Medicine - Nephrology, Columbia University Medical Center, New York, NY, 2Columbia University Medical Center, New York, NY

    *Purpose: Given recent attention on the impact of the race coefficient in equations for estimated glomerular filtration rate (eGFR) on racial disparities in kidney transplantation,…
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