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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Impact of Immunosuppression on T-cell Responses After mRNA-Based Sars-CoV-2 Vaccination

    E. Wong1, N. L. Bert2, H. K. Sran1, A. Lim1, M. D'Costa1, K. Akalya2, S. Hang2, A. Bertoletti2, A. Vathsala1

    1National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore, 2Programme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore

    *Purpose: Administration of mRNA-based SARS-CoV-2 vaccines confers protection from SARS-CoV-2 infection and reduces its severity in the general population. It has been suggested that mounting…
  • 2022 American Transplant Congress

    Sex- and Insurance- Based Disparities in Listing for and Benefit from Simultaneous Heart-Kidney Transplant

    B. Wayda1, X. S. Cheng1, P. Garcia1, S. Sanoff2, L. M. McElroy2, K. K. Khush1

    1Stanford University School of Medicine, Stanford, CA, 2Duke University School of Medicine, Durham, NC

    *Purpose: Rates of simultaneous heart-kidney (SHK) transplant vary widely in the United States (US). Absent uniform eligibility criteria, sex and insurance status could influence patient…
  • 2022 American Transplant Congress

    Impact of Early Corticosteroid Withdrawal on Simultaneous Pancreas-Kidney Transplant Long-Term Outcomes: Single Center Experience and Comparison to the International Pancreas Transplant Registry

    D. Pierce1, A. Lichvar2, A. Gruessner3, I. Tang1, P. DiCocco1, M. Spaggiari1, I. Tzvetanov4, E. Benedetti1, M. Campara1

    1University of Illinois at Chicago, Chicago, IL, 2University of California San Diego Health, San Diego, CA, 3SUNY Downstate Medical Center, Brooklyn, NY, 4University of Illinios at Chicago, Chicago, IL

    *Purpose: The purpose of this study is to assess the long-term efficacy and safety of early corticosteroid withdrawal (ESW) compared to corticosteroid maintenance (CCS) immunosuppression…
  • 2022 American Transplant Congress

    A Conceptual Framework for Supporting Living Kidney Donors Throughout the Donation Process

    C. Killian, H. Qu, R. Reed, C. Woods, G. Owens, A. Carter, V. Kumar, M. J. Hanaway, I. Herbey, N. Ivankova, R. Shewchuk, J. Locke

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: The majority of programs aimed to increase living donor kidney transplantation (LDKT) address transplant candidates’ needs, not those of potential donors. The Living Donor…
  • 2022 American Transplant Congress

    Two-Week Protocol Biopsy in Renal Allograft: Feasibility, Safety, and Outcomes

    M. Lim1, K. Lee2

    1Samsung Medical Center, Seoul, Korea, Republic of, 2Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: Protocol biopsy in renal allograft helps to early detect subclinical rejection (SCR) in patients who have no abnormal clinical and laboratory findings. Still, there…
  • 2022 American Transplant Congress

    T-cell Depletion vs. Il-2 Receptor Blockade in Pancreas Transplantationt-Cell Depletion vs. Il-2 Receptor Blockade in Pancreas Transplantation

    F. Aziz, S. Parajuli, D. Kaufman, J. Odorico, D. Mandelbrot

    University of Wisconsin, Madison, WI

    *Purpose: Because of the higher immunological risk associated with pancreas compared to kidney transplantation, many have assumed that T depleting induction is required for pancreas…
  • 2022 American Transplant Congress

    Is BK After SPK Okay?: Kidney and Pancreas Transplant Outcomes After BK Viremia

    G. Dube1, K. McCune2, D. Cohen3, L. Ratner2, S. Husain1

    1Columbia University Medical Center, New York, NY, 2Columbia University, New York, NY, 3Columbia University Med Ctr, New York, NY

    *Purpose: BK viremia and BK nephropathy (BKN) are common after kidney transplant alone, occurring in ~15% and ~1-10%, and are associated with an increased risk…
  • 2022 American Transplant Congress

    Comparative Outcomes at a Single Center for 71 Deceased Donor Kidney Transplants from Donors with Sars-CoV-2 RNA Detection

    C. E. Koval1, E. Poggio2, M. Eltemamy3, Y. Lin2, M. Duck4, N. Shrestha5, A. Wee2

    1Cleveland Clinic Foundation, Cleveland, OH, 2Cleveland Clinic, Cleveland, OH, 3The Cleveland Clinic, Cleveland, OH, 4Nephrology, Cleveland Clinic Foundation, Cleveland, OH, 5Infectious Diseases, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Extra-pulmonary organs from donors with SARS-CoV-2 detection during donor evaluation are not accepted by many centers due to theoretical concerns for productive infection and…
  • 2022 American Transplant Congress

    Molecular Associations in Kidney Transplant Biopsies in the Trifecta Study Indicate That at Least Three Distinct Processes Release Dd-cfDNA: ABMR, TCMR, and Injury

    P. F. Halloran1, J. Reeve1, K. S. Madill-Thomsen1, Z. Demko2, A. Prewett2, P. Billings2, .. and the Trifecta Investigators3

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2Natera Inc., San Carlos, CA, 3., ., AB, Canada

    *Purpose: In the Trifecta study (ClinicalTrials.gov # NCT04239703 53), elevated plasma dd-cfDNA is associated with molecular rejection in kidney transplant indication biopsies, particularly active ABMR…
  • 2022 American Transplant Congress

    Does Machine Perfusion of Heart for Donation After Cardiac Death (DCD) Transplantation Affect Other Organ Outcomes?

    R. Misawa1, K. Okumura2, H. Sogawa1, G. Veillette1, A. Dhand3, R. Bodin4, D. C. Wolf4, B. Partiula4, D. John1, T. Diflo5, S. Nishida1

    1Department of Surgery, Transplant, Westchester Medical Center/New York Medical College, Valhalla, NY, 2Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY, 3Department of Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, 4Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, 5Westchester Medical Center/New York Medical College, Valhalla, NY

    *Purpose: Machine perfusion of heart for donation after cardiac death (DCD) transplants is being increasingly utilized. Initial protocol of the heart machine perfusion for the…
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