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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    BiomarkeR Initiative to Advance Transplantation OutcomEs in Children (BRITE-c) Analysis

    M. E. Seifert1, L. Sheward2, A. Kho2, N. Rodig2, V. Dharnidharka3, M. Diehl2, R. B. Mannon4, O. Bestard5, T. Blydt-Hansen6, D. M. Briscoe2

    1University of Alabama, Birmingham, AL, 2Boston Children's Hospital, Boston, MA, 3St Louis Children's Hospital, St Louis, MO, 4University of Nebraska, Omaha, NE, 5Bellvitge University Hospital, Barcelona, Spain, 6BC Childrens, Vancouver, BC, Canada

    *Purpose: Recent studies indicate that 25-36% of clinically stable pediatric renal transplant recipients will have subclinical rejection detected on surveillance biopsy. These findings highlight a…
  • 2022 American Transplant Congress

    Longevity Matching for Living Donor Renal Transplantation

    S. Karhadkar1, J. Dawes1, K. Wirshup1, J. Kolansky1, A. Gregor1, A. Diamond2, A. DiCarlo1

    1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA

    *Purpose: Living donor kidney transplantation (LDKT) continues to become a more prevalent treatment method for ESRD and is known to increase both organ availability and…
  • 2022 American Transplant Congress

    Outcomes of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists in Diabetic Kidney Transplant Recipients

    T. S. Mahmoud1, J. Yagan1, A. Hasan2, O. Gheith1, M. Mostafa1, S. Rida1, N. El-Serwy1, M. Shaker1, M. Khalid1, P. Nair1, T. Alotaibi1

    1Nephrology, Organ Transplant Center, Kuwait, Kuwait, 2Immunometabolism, Dasman Diabetes Center, Kuwait, Kuwait

    *Purpose: The impact of the new glucose lowering therapies, sodium-glucose cotransporter 2 inhibitors (SGLT2i) and Glucagon-like peptide-1 receptor agonists (GLP-1RA), on managing patients with type…
  • 2022 American Transplant Congress

    Six-Month Outcomes Among Lung Transplant Patients with COVID-19

    L. D. Mahan, J. Rose, M. Mohanka, A. Banga

    UT Southwestern Medical Center, Dallas, TX

    *Purpose: There is limited data on the outcomes beyond the acute illness among lung transplant (LT) patients with Coronavirus disease 2019 (COVID-19). The current study…
  • 2022 American Transplant Congress

    Risk of Post-Transplant Lymphoproliferative Disease After Anti-Thymocyte Globulin in Childhood Solid-Organ Transplant Recipients

    A. M. McKay1, C. Teoh1, J. Vasilevska-Ristovka2, J. Browne2, T. Banh2, A. Dipchand1, V. Ng1, M. Solomon1, U. Allen1, Y. Avitzur1, R. Parekh3

    1Transplant & Regenerative Medicine Centre, The Hospital for Sick Children, Toronto, ON, Canada, 2Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, 3Division of Nephrology, Department of Medicine, Women’s College Hospital and University Health Network, Toronto, ON, Canada

    *Purpose: Determine if the use of anti-thymocyte globulin (ATG) in pediatric solid organ transplant recipients was associated with an increased risk of post-transplant lymphoproliferative disorder…
  • 2022 American Transplant Congress

    CD14+ Monocytes Play a Critical Role in Initiating Xeno-Recognition, Costimulation and Immune-Responses to Porcine Endothelial Cells

    H. Xu, A. Kirk, H. Xu

    Duke University School of Medicine, Durham, NC

    *Purpose: Porcine endothelial cells (PECs) are the first barrier between a pig’s organ and circulating immune system. Unlike allogeneic immune responses, PECs fail to induce…
  • 2022 American Transplant Congress

    Do Clinical & Pathologic Signs of Rejection Develop Following Transplantation of Tissue Containing Non-Autologous Mitochondria in an Autologous Nuclear Cloned Host?

    S. Jacob1, M. L. Baack2, A. Savinov3, P. J. Wettstein4

    1Cardiothoracic Surgery and transplantation, Mayo Clinic, Jacksonville, FL, 2Division of Neonatology, University of South Dakota – Sanford School of Medicine, Sioux Falls, SD, 3Sanford Research, University of South Dakota School of Medicine, Sioux Falls, SD, 4Departments of Surgery and Immunology, Mayo Clinic, Rochester, MN

    *Purpose: Recent studies have yielded conflicting results on the capacity of oocyte-encoded mtDNA polymorphisms to stimulate rejection . Therefore, there are still questions as to…
  • 2022 American Transplant Congress

    BMI Trajectory and Attributable Risk of New Onset Hypertension Among Obese Living Kidney Donors

    R. D. Reed1, M. C. McLeod1, P. A. MacLennan1, V. Kumar1, S. E. Brooks1, A. G. Maynor1, L. A. Stanford1, G. A. Baker1, C. A. Schinstock2, J. R. Silkensen3, G. R. Roll4, D. L. Segev5, B. J. Orandi1, C. E. Lewis6, J. E. Locke1

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 3Medicine, Hennepin County Medical Center, Minneapolis, MN, 4Surgery, University of California San Francisco, San Francisco, CA, 5Surgery, Johns Hopkins University, Baltimore, MD, 6Epidemiology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Obesity increases hypertension risk in general and living kidney donor populations. Risk attributable to donation in the context of obesity and whether that risk…
  • 2022 American Transplant Congress

    Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation

    C. López del Moral1, N. Lachmann2, S. Hergovits2, D. Stauch2, A. Akifova3, M. Naik3, B. Osmanodja3, D. Schmidt3, K. Budde3

    1Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, 3Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany

    *Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…
  • 2022 American Transplant Congress

    Early Outcomes for Liver Transplant with Thoracoabdominal Normothermic Regional Perfusion for Donation After Circulatory Death: A Multi-Center Experience

    A. L. Brubaker1, A. Lee1, B. Jackson1, J. Berumen1, J. R. Parekh1, K. L. Mekeel1, A. R. Gupta2, J. M. Gardner2, T. Chaly3, A. K. Mathur4, C. Jadlowiec4, K. Reddy4, R. Nunez4, J. Bellingham5, E. Thomas6, J. R. Wellen7, M. Kearns1, V. Pretorius1, G. T. Schnickel1

    1UC San Diego, San Diego, CA, 2UC San Francisco, San Francisco, CA, 3Arizona Transplant Associates, Phoenix, AZ, 4Mayo Clinic Arizona, Phoenix, AZ, 5California Pacific Medical Center, Orinda, CA, 6University of Texas, San Antonio, TX, 7Washington University, Saint Louis, MO

    *Purpose: We evaluated early outcomes of liver transplant after thoracoabdominal normothermic regional perfusion (TA-NRP) for controlled donation after circulatory death (cDCD) donors.*Methods: We identified liver…
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