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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Impact of Cyp 3a5 Genotype on Lcp Tacrolimus Dosing and Monitoring in Kidney Transplantation

    D. J. Taber, T. Carcella, N. Patel, F. Bartlett, A. Posadas, V. Rao, M. Casey, V. Rohan, D. Dubay, D. Taber

    Med Univ of South Carolina, Charleston, SC

    *Purpose: LCP Tacrolimus has a recommended de novo starting dose of 0.14 mg/kg/day in kidney transplantation (KTR). There is limited data on the influence of…
  • 2022 American Transplant Congress

    Kidney Transplantation Utilizing SARS-CoV-2 Rt-PCR Positive Donor Kidneys with Immediate Post Exposure Casirivimab /Imdevimab Followed by Thymoglobulin Induction

    S. K. Patel1, E. Siskind1, M. Laftavi1, J. Splinter1, E. Shipman2, S. Shah1, S. Nijim1, A. Adekile1, S. Asad1

    1Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV, 2Nevada Donor Network, Las Vegas, NV

    *Purpose: At the beginning of the pandemic, kidneys from SARS-CoV-2 (COVID) RT-PCR positive donors were not utilized for transplantation, due to the risk of viral…
  • 2022 American Transplant Congress

    Safety and Efficacy at 4 Years in Post-Liver Transplant Patients with Chronic Kidney Disease Receiving Tenofovir Alafenamide (TAF) for HBV Prophylaxis

    E. Gane1, B. George1, D. Ray-Chaudhuri1, T. Mules1, C. D. Holt2, H. Wang2, V. Suri2, A. Gaggar2, A. Osinusi2, J. Flaherty2

    1Auckland City Hospital and University of Auckland, Auckland, New Zealand, 2Gilead Sciences, Inc., Foster City, CA

    *Purpose: Recommended antiviral prophylaxis to prevent recurrent HBV infection after liver transplantation includes tenofovir disoproxil fumarate (TDF). However, given risks of bone/renal toxicity associated with…
  • 2022 American Transplant Congress

    Mitochondrial Dysfunction and Alloimmunity in Chronic Lung Transplant Rejection

    M. Cano1, D. Zhou2, C. Chen3, K. Pugh4, D. Byers1, D. Kreisel5, R. Hachem1, A. Gelman5

    1Pulmonary and Critical Care, Washington University, Saint Louis, MO, 2Surgery, Washington University, Saint Louis, MO, 3Pulmonary and Critical Care, UT Southwestern Medical Center, Dallas, TX, 4Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 5Surgery and Immunology and Pathology, Washington University, Saint Louis, MO

    *Purpose: Bronchiolitis obliterans syndrome (BOS) remains a major cause of death after lung transplantation. Unfortunately, we lack effective treatments for BOS as the mechanisms by…
  • 2022 American Transplant Congress

    Functional Status Assessment in Kidney Transplant Candidates and Recipients: A Single-Center Experience

    M. Marshall, O. A. Moss, G. Friedman, O. A. Moss

    UC Davis Transplant Center, Sacramento, CA

    *Purpose: Functional status assessment (FSA) is important to kidney transplant (KT) candidacy evaluation; a low Fried Frailty score (FFS) is associated with poor waitlist and…
  • 2022 American Transplant Congress

    Managing Medications During a Pandemic: A Mixed-Methods Study of Perception of Adult Kidney Transplant Recipients and Those Waiting for a Kidney Transplant

    M. R. Wakefield1, C. M. Ashbaugh2, C. Richardson2, M. B. Stephens2, P. Yerram3, M. Freiburghaus4, M. Mercedes4, C. L. Russell4

    1Surgery/Urology, University of Missouri School of Medicine, Columbia, MO, 2Transplant, University of Missouri Health Care, Columbia, MO, 3Nephrology, Harry S Truman VA Hospital, Columbia, MO, 4University of Missouri-Kansas City, Kansas City, MO

    *Purpose: Patients interact with healthcare providers (HCP) and pharmacists to manage medications. Little is known about the impact of COVID-19 on medication management. The purpose…
  • 2022 American Transplant Congress

    Safety and Mortality Benefit of Direct Oral Anticoagulants in Kidney Transplant

    C. Firth, M. Apolinario, F. Shamoun, E. Lim, N. Zhang, M. Keddis

    Mayo Clinic, Scottsdale, AZ

    *Purpose: Direct oral anticoagulants (DOACs) are increasingly used in renal transplant recipients (RTR). We aim to identify bleeding events and all-cause mortality between DOACs and…
  • 2022 American Transplant Congress

    Impact of Sub-therapeutic Tacrolimus Troughs at Discharge from Index Admission on Short-Term Outcomes in Kidney Transplant Recipients Receiving Rabbit Anti-Thymocyte Globulin Induction

    X. Liu1, J. Trofe-Clark2, D. Sawinski3, B. Steiner1, S. Sharma1, S. Witek1, T. Fallah2, M. Norris2, C. Sammons2, G. Malat2

    1Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, 2Penn Transplant Institute and Pharmacy Dept, Hosp of Univ of Pennsylvania, Philadelphia, PA, 3Penn Transplant Institute, Hosp of Univ of Pennsylvania, Philadelphia, PA

    *Purpose: Kidney transplant (KTx) recipients are often discharged with subtherapeutic tacrolimus (TAC) troughs due to short hospital lengths of stay (LOS) for index KTx admissions.…
  • 2022 American Transplant Congress

    Racial Differences in the Predictability of Donor-Derived Cell-Free DNA Among Renal Transplant Recipients

    M. D. Williams1, N. Nimmagadda1, S. Patel2, O. Olaitan1

    1Rush University Medical Center, Chicago, IL, 2CareDx, Brisbane, CA

    *Purpose: Donor-Derived Cell-Free DNA (dd-cfDNA) is used to monitor for allograft rejection following renal transplantation. Baseline dd-cfDNA is higher in African American (AA) patients compared…
  • 2022 American Transplant Congress

    Outcomes in Elderly Black Renal Transplant Recipients Receiving Basiliximab Induction and Early Steroid Withdrawal

    E. Garcia, T. Sparkes, A. Szczepanik, S. Bova, J. Bromberg, A. Haririan, J. Casale

    University of Maryland Medical Center, Baltimore, MD

    *Purpose: Black renal transplant recipients (RTR) carry a higher risk of rejection (BPAR) and graft loss due to immunologic and non-immunologic factors. Lymphocyte depleting induction…
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