ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Does Black Race Modify the Risk of Transplant Failure Associated with HLA Mismatch in First Adult Kidney Allografts from Deceased Donors?

    K. Atiemo

    Tulane University, New Orleans, LA

    *Purpose: Current US- based data suggests Black patients awaiting kidney re-transplantation are more likely to be highly sensitized compared to other races. Degree of HLA…
  • 2022 American Transplant Congress

    Acute Cellular Rejection in Liver Transplant Recipients Following Vaccination Against Covid-19

    R. Sarwar1, O. Adeyi2, N. Lim1

    1Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, 2Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: The coronavirus disease 2019 (COVID-19) global pandemic has seen the development of effective vaccines in record time. We report a series of five liver…
  • 2022 American Transplant Congress

    DonorNet Procurement Photos and Their Association with Kidney Utilization

    M. Stuart1, A. M. Placona1, C. Martinez1, K. Andreoni2

    1United Network for Organ Sharing, Richmond, VA, 2University Hospitals, Case Western University, Cleveland, OH

    *Purpose: Procurement teams can upload backbench photos of organs to DonorNet. It is unclear if these photos are associated with kidney utilization. We examined the…
  • 2022 American Transplant Congress

    National Consortium Registry Insights on Management and Outcome of Hepatitis C Viremic Heart Transplants

    R. Gottlieb1, M. Salem1, A. Ravichandran2, J. Kennedy3, J. Strope4, S. Lin5, J. Chow6, P. Eckman7, S. Desai8, O. Larkins1, J. Vanzyl1, S. Hall1

    1Baylor Scott & White Healthcare, Dallas, TX, 2Ascension Medical Group, Indianapolis, IN, 3Inova Heart and Vascular Institute, Falls Church, VA, 4Medical University of South Carolina, Charleston, SC, 5University of Washington Medical Center, Seattle, WA, 6Tufts Medical Center, Boston, MA, 7Minneapolis Heart Institute, Minneapolis, MN, 8Ochsner Medical Center, New Orleans, LA

    *Purpose: Multicenter US registry of clinical management of HCV NAT+ hearts.*Methods: An ongoing 8-center retrospective IRB-approved registry collected baseline characteristics, labs, management, and outcomes after…
  • 2022 American Transplant Congress

    Microvascular Inflammation in Kidney Transplant Biopsies in the Absence of HLA-DSA Displays Intense Cytotoxic T-cell and NK Cell but Not Plasma Cell Infiltration

    A. Buxeda1, L. Llinàs-Mallol1, J. Gimeno2, D. Redondo-Pachón1, C. Arias-Cabrales1, C. Burballa1, A. Puche2, M. Pérez-Sáez1, J. Pascual3, M. Crespo1

    1Nephrology Department, Hospital del Mar, Institute Mar for Medical Research (IMIM), Barcelona, Spain, 2Pathology Department, Hospital del Mar, Institute Mar for Medical Research (IMIM), Barcelona, Spain, 3Nephrology Department, Hospital Universitario 12 de Octubre. Institute Mar for Medical Research (IMIM), Madrid, Spain

    *Purpose: Microvascular inflammation (MVI) without evidence of HLA-donor-specific antibodies (HLA-DSA) or C4d+ deposition remains an enigmatic phenotype, which cannot be classified as antibody-mediated rejection (ABMR)…
  • 2022 American Transplant Congress

    Immunity Rates to Hepatitis B Among Solid Organ Transplant Recipients

    S. Kopf1, J. Walker2, K. Bruxvoort3, H. Budhwani3, A. Nellore4

    1Infectious Disease, University of Alabama at Birmingham Hospital, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3University of Alabama at Birmingham Hospital, Birmingham, AL, 4University of Alabama, Birmingham, AL

    *Purpose: Immunosuppression after transplantation decreases vaccine responsiveness. Thus, to be best protected from post-transplant communicable diseases, vaccination of organ transplant candidates in the pre-transplant period…
  • 2022 American Transplant Congress

    A Novel Approach to Non-Invasive Multimodality Testing with Allosure and Allomap Predicts Microvascular Inflammation with High Accuracy in Kidney Transplant Recipients

    S. Parajuli, F. Aziz, N. Garg, S. E. Panzer, K. Van Hyfte, K. Degner, S. Reese, L. Ptak, N. Wilson, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: The most prominent histologic lesion in antibody-mediated rejection (ABMR) is microvascular inflammation (MVI); however, its recognition and scoring can be challenging and poorly reproducible…
  • 2022 American Transplant Congress

    High TTV Load Before First Vaccine Dose is Associated with Poor Serological Response to Covid-19 Vaccination in Lung Transplant Recipients

    C. C. Van Leer Buter1, R. A. Hoek2, E. A. Verschuuren3, R. D. de Vries4, D. van Baarle1, M. van der Heiden1, H. G. Niesters1, C. GeurtsvanKessel4

    1Dept. of Medical Microbiology, University Medical Center Groningen, Groningen, Netherlands, 2Dept. of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 3Dept. of Pulmonary Diseases,, University Medical Center Groningen, Groningen, Netherlands, 4Dept. of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: Torque tenovirus (TTV), a highly prevalent virus which is not known to cause pathology in humans, is currently being investigated as a marker of…
  • 2022 American Transplant Congress

    Analysis of Sars-Cov-2-Specific T-Cell Responses Using Novel Single-Cell Multiplexed Isolight in Covid-19 Convalescents

    Y. Sambandam1, J. He1, N. Vanderhyde2, L. Gallon1, J. Leventhal1, J. Mathew1

    1Northwestern University, Chicago, IL, 2IsoPlexis, Branford, CT

    *Purpose: COVID-19 has poor outcomes in transplant recipients with reduced antibody responses. However, the exact cellular immune response against SARS-CoV-2 remains largely unclear. We developed…
  • 2022 American Transplant Congress

    Barriers to Completing the Transplant Evaluation Process: A Mixed-Methods Study

    E. J. Gordon1, J. J. Uriarte1, A. N. McLagan1, B. Kuramitsu1, J. Gacki-Smith1, M. Shumate2, L. McElroy3, J. Caicedo1

    1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University, Evanston, IL, 3Duke University, Durham, NC

    *Purpose: Little is known about patient-reported factors affecting patients’ access to the kidney transplant waitlist after starting evaluation. We qualitatively assessed patients’ perceived barriers to…
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