Am J Transplant, Volume 22, Suppl 3 Archives - Page 3 of 190 - ATC Abstracts

2022 American Transplant Congress
Cell-free Amniotic Fluid Reduces Liver Inflammation And Fibrosis
F. Ditmars¹, C. Bowen¹, N. Liu¹, K. L. Pereira de Castro¹, J. Johnson¹, M. Kueht¹, A. Saad², H. L. Stevenson³, J. Fair¹, W. S. Fagg¹
¹Surgery, University of Texas Medical Branch, Galveston, TX, ²Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, ³Pathology, University of Texas Medical Branch, Galveston, TX
*Purpose: Effective interventions for hepatic inflammation and fibrosis remain a dire unmet need in transplant medicine. Cell-free amniotic fluid (AF) represents a potential alternative to…
2022 American Transplant Congress
Lung Transplantation For COVID Acute Respiratory Distress Syndrome: A Pediatric And Adult Case Series
C. Arendale¹, D. Kumar², P. S. Garcha³, C. Kutac⁴, G. Loor¹, A. Rana¹, J. Goss¹, N. Galvan¹
¹Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, ²Department of Biochemistry, Baylor College of Medicine, Houston, TX, ³Department of Medicine, Baylor College of Medicine, Houston, TX, ⁴Baylor St. Luke’s Medical Center, Houston, TX
*Purpose: Lung transplantation (LTx) has been shown to be a viable treatment for irreversible lung disease caused by COVID-19. Given the limited data on the…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
Clinical Efficacy of Adjuvant Immunotherapy for Liver Transplant Recipients with Exceeding Japan Criteria of Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells
M. Ohira¹, Y. Imaoka², K. Sato³, K. Imaoka¹, N. Tanimine¹, H. Tahara¹, K. Ide¹, T. Kobayashi¹, Y. Tanaka¹, A. G. Tzakis⁴, S. Nishida⁵, H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²Hiroshima Uni., Hiroshima, Japan, ³Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan, ⁴Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, OH, ⁵Univ of Miami School of Medicine, Valhalla, NY
*Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
2022 American Transplant Congress
Longitudinal Analysis of the Lung Microbiome and Immune Status in Lung Transplant Recipients
Y. Zhao, P. Zhang, Y. Su, Y. Zhu, L. Shen
Shanghai Pulmonary Hospital, Shanghai, China
*Purpose: The dynamic remodeling of lung flora structure and the association between microbial community dynamics and immune status after lung transplantation (LTx) remain unclear.*Methods: Fourteen…
2022 American Transplant Congress
Characterizing the Landscape of Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation
J. D. Motter¹, K. Jackson¹, K. Yu², R. M. Pfeiffer², A. Massie¹, J. Garonzik-Wang³, D. Segev¹, E. A. Engels²
¹Johns Hopkins University, Baltimore, MD, ²National Cancer Institute, Bethesda, MD, ³University of Wisconsin-Madison, Madison, WI
*Purpose: Incompatible living donor kidney transplant recipients (ILDKTr) require desensitization to facilitate transplantation across donor-specific antibody (DSA); however, this substantial upfront immunosuppression may result in…
2022 American Transplant Congress
First Report of Xenotransplantation from a Pig to Human Recipient
J. Stern¹, V. Tatapudi¹, B. Lonze¹, Z. Stewart¹, M. Mangiola¹, M. Wu¹, S. Mehta¹, E. Weldon¹, R. Dieter¹, N. Lawson¹, A. Griesemer², B. Parent¹, G. Piper¹, P. Sommer¹, S. Cawthon¹, B. Sullivan¹, N. Ali¹, R. A. Montgomery¹
¹NYU Langone Transplant Institute, New York, NY, ²CUMC, New York, NY
*Purpose: Xenotransplantation of genetically edited pig organs into human recipients can solve the global scarcity of organs for transplantation. Humans lack the α1,3-Gal glycan ubiquitously…
2022 American Transplant Congress
2021 Outcomes Analysis Of U.S. Transplant Centers Performing High Volumes Of Hard To Place Kidneys
D. Bahl¹, A. Mahajan², M. Smogorzewski³, Y. A. Qazi⁴
¹St. George's University, St Georges, Grenada, ²University College Cork School Of Medicine, Cork City, Ireland, ³Keck Medical Center at USC, los angeles, CA, ⁴Keck Medical Center at USC, LOS ANGELES, CA
*Purpose: Despite a growing number of patients awaiting a kidney transplant, discard rate remains significantly high. The UNOS SRTR data now provides information on all…
2022 American Transplant Congress
Validation of a Prediction System for Risk of Allograft Loss (iBOX) in Pediatric Kidney Transplant Recipients
J. Hogan¹, G. Divard², R. Garro³, O. Boyer⁴, M. Seifert⁵, J. Smith⁶, B. Toenshoff⁷, K. Twombley⁸, B. Warady⁹, P. Weng¹⁰, R. Zaar¹¹, R. Patzer¹², A. Loupy²
¹Pediatric Nephrology, Robert Debré Hospital, APHP, Paris, France, ²Paris Transplant Group, INSERM, Paris, France, ³Pediatric Nephrology, Children Healthcare of Atlanta, Atlanta, GA, ⁴Pediatric Nephrology, Necker Hospital, Paris, France, ⁵UAB School of Medicine, Birmingham, AL, ⁶Pediatric Nephrology, Seattle Children, Seattle, WA, ⁷University Children's Hospital, Heidelberg, Germany, ⁸Medical University of South Carolina, Charleston, SC, ⁹Childrens Mercy Hospital, Kansas City, MO, ¹⁰Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, ¹¹Pediatric Nephrology, Le Bonheur Children's Hospital, Memphis, TN, ¹²Emory Transplant Center, Emory University, Atlanta, GA
*Purpose: Kidney allograft loss is a common cause of end-stage renal disease but accurate prediction models of kidney allograft loss are lacking in children. The…
2022 American Transplant Congress
Which is More Important for Predicting De Novo DSA Production, B Cell Epitope (EPLET) or T Cell Epitope (PIRCHE) Analysis ?
T. Kobayashi¹, T. Tomosugi², S. Sakamoto², S. Ashimine¹, K. Iwasaki¹, M. Niemann³, E. Spierings⁴, Y. Miwa¹, M. Okumura¹, K. Ishiyama¹, A. Takeda², N. Goto², S. Narumi², Y. Watarai²
¹Aichi Medical University School of Medicine, Nagakute, Japan, ²Nagoya Daini Red Cross Hospital, Nagoya, Japan, ³PIRCHE AG, Berlin, Germany, ⁴UMC Utrecht, Utrecht, Netherlands
*Purpose: De novo donor-specific antibodies (dnDSA) can cause chronic ABMR, resulting in poor prognosis. Recently, mismatch at B cell epitope level, i.e. EPLET mismatch, has…