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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Knowledge Gaps and Perceptions of Liver Disease and Liver Transplant Referral Serve as Barriers to Transplant Among Primary Care Providers in Non-Urban America

    M. Wright1, V. Madabhushi1, A. R. Garcia2, N. Pope2, A. Murphy3, C. N. Taylor1, R. Gedaly1, M. Gupta1

    1Surgery, University of Kentucky, Lexington, KY, 2College of Social Work, University of Kentucky, Lexington, KY, 3School of Public Health, University of Kentucky, Lexington, KY

    *Purpose: The path to liver transplant (LTX) typically begins with primary care providers(PCPs), and is dependent on timely referral to transplant centers. The referral patterns…
  • 2022 American Transplant Congress

    Recipient and Center Factors Associated with Immunosuppression Practice Beyond the First Year After Liver Transplantation

    T. Bittermann1, D. Goldberg2

    1University of Pennsylvania, Philadelphia, PA, 2University of Miami, Miami, FL

    *Purpose: To investigate patient and center factors associated with differences in immunosuppression management in the first 5 years after LT.*Methods: A retrospective cohort of 11,326…
  • 2022 American Transplant Congress

    Evaluation of Compliance and Efficacy with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Tacrolimus in Kidney Transplant Recipients

    M. Nikirk1, J. Chen1, E. Tillman2

    1Indiana University Health, Indianapolis, IN, 2Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The purpose of this study is to evaluate compliance and efficacy of The Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 genotype guided tacrolimus…
  • 2022 American Transplant Congress

    Simultaneous Liver/ Kidney Transplant Reduces Both Donor Specific and Non-Donor Specific HLA Antibodies

    X. Zhang, S. Wisel, I. Kim, S. Jordan

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Kidney allografts can be transplanted across strong donor specific antibody (DSA) barriers in simultaneous liver/kidney transplant (SLK) recipients. It is suggested that preformed DSAs…
  • 2022 American Transplant Congress

    Dendritic Cell Senescence as a Key Contributor to Transplant Rejection

    J. Zhao1, X. Li1, S. Jung1, H. Zhang1, V. Kasinath1, J. Azzi1, P. Sage1, J. Bromberg2, R. Abdi1

    1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…
  • 2022 American Transplant Congress

    Improving Access and Equity for Transplant: A Single-Center Experience

    S. Kodali1, A. Lopez2, C. Egwim2, J. Alegria2, S. Yi2, H. Adrogue2, M. Moaddab2, H. Huang2, I. Hussain2, M. Kassi2, J. Ontiveros2, R. Guardiola2, J. Alexander2, D. Harvey2, K. Maresh2, S. Zylicz2, L. Loza2, J. Corkrean2, A. O. Gaber2, R. M. Ghobrial1

    1Sherrie and Alan Conover Center for Liver Disease & Transplantation, Houston Methodist Hospital, Houston, TX, 2Houston Methodist Hospital, Houston, TX

    *Purpose: Many Hispanic Americans have misconceptions about transplantation due to language and cultural differences, which can make them less likely to undergo liver transplant (LT)…
  • 2022 American Transplant Congress

    Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation

    R. Choudhury1, A. Rouhi2, G. Hoeltzel3, Y. Bababekov1, A. Suarez-Pierre4, A. Yule1, N. Vigneshwar4, N. Williams5, K. Dumon2, T. Nydam1

    1Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 3General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, 4Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, 5General Surgery, Hospital of the University of Pennsylvania, Aurora, CO

    *Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…
  • 2022 American Transplant Congress

    Failure to Account for Social Determinants of Health in Non-HCC MELD Exceptions Exacerbates Geographic Disparities in Access to Liver Transplantation

    R. M. Cannon, P. MacLennan, S. S. Sheikh, B. J. Orandi, A. Nasell, J. T. Walker, J. E. Locke

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Non-HCC MELD exceptions have been previously shown to give excess priority for transplant in certain UNOS Regions, but this phenomenon has not been examined…
  • 2022 American Transplant Congress

    Liver Transplantation for Patients with Fibrolamellar Hepatocellular Carcinoma: A Comprehensive Multicenter Analysis to Support Future Decision Making

    M. P. Claasen1, T. Ivanics1, W. G. Polak2, J. N. IJzermans2, G. Sapisochin1

    1Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada, 2HPB and Transplant Surgery, Erasmus MC, Rotterdam, Netherlands

    *Purpose: Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare tumour accounting for ~1% of all primary liver cancers. Due to its rarity, there is a shortage…
  • 2022 American Transplant Congress

    Metabolic Outcomes After Pancreas Transplant Alone from Donation After Circulatory Death Donor – The UK Registry Analysis

    J. Gopal, A. McLean, A. Muthusamy

    Imperial College Renal and Transplant Center, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: Extrapolating data from early DCD (donation after circulatory death) kidney transplantation, pancreas transplants from DCD grafts were feared to have worse metabolic outcomes. Hence,…
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