2022 American Transplant Congress
Deletion of AIF-1 Promotes Kidney Reparative Macrophages and Prevents Fibrosis
Duke University School of Medicine, Durham, NC
*Purpose: A major etiology contributing to poor allograft survival is the inevitable ischemic insult it incurs during transplantation. Macrophages are key players in ischemia-reperfusion injury,…2022 American Transplant Congress
Urine-based Assay For Detection Of Acute Rejection In Pediatric Kidney Transplant Recipients
*Purpose: Biomarkers such as donor-derived cell free DNA (cfDNA) and gene expression profiling are utilized in adult transplant patients (pts), but these tests lack sensitivity…2022 American Transplant Congress
Benefit of Kidney Transplantation for Post Lung Transplantation Renal Failure: Need for Priority Allocation
1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA
*Purpose: Nephrotoxicity is a major side effect of thoracic transplantation. Many patients will eventually require renal transplantation (KAL) to manage their developing ESRD. Recently, simultaneous…2022 American Transplant Congress
Low-Quality Kidney Allograft Use in Kidney Transplantation is Associated with a Prolonged Post-Transplant Length of Stay
*Purpose: The purpose of this study is to determine the effect of low-quality kidney allografts on recipient hospital length of stay following transplant using five…2022 American Transplant Congress
Safety and Efficacy of SGLT-2 Inhibitors in Solid Organ Transplant Recipients
Pharmacy, Tampa General Hospital, Tampa, FL
*Purpose: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have been shown to improve glycemic control, blood pressure, cardiovascular mortality, and preserve kidney function in the general population.…2022 American Transplant Congress
Dynapenia Among Kidney Transplant Candidates and Recipients in the United States
*Purpose: Among Kidney Transplant (KT) patients, sarcopenia, loss of muscle mass, is prevalent and has been associated with post-KT mortality. The burden of dynapenia, an…2022 American Transplant Congress
Outcomes of Kidney Transplantation from a Male Donor with a Highly Elevated Prostate Specific Antigen Level (PSA) in Female Recipients
Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV
*Purpose: Donor derived malignancy is a contraindication for kidney transplantation. Published literature is devoid of instances of utilization of organs from donors with high PSA…2022 American Transplant Congress
Cardiovascular Outcomes of Kidney Transplant Recipients Receiving Belatacept Compared to a Matched Tacrolimus
*Purpose: Tacrolimus (TAC), a calcineurin inhibitor (CNI), is the backbone of maintenance immunosuppression in kidney transplant recipients (KTR) but has been associated with cardiovascular (CV)…2022 American Transplant Congress
Adding Epitope Compatibility To Deceased Donor Kidney Allocation Criteria: Recommendations From An Online Public Deliberation
*Purpose: With increasing demand for kidneys and a scarce supply, ways to reduce rejection and improve transplant outcomes are needed. One possibility is using epitope…2022 American Transplant Congress
Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19
1University of Pittsburgh, Pittsburgh, PA, 2UPitt, Pittsburgh, PA, 3Allovir, Waltham, MA
*Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
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