Am J Transplant, Volume 22, Suppl 3 Archives - Page 25 of 190 - ATC Abstracts

2022 American Transplant Congress
Histopathology at Diagnosis and One-Year Outcomes in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Preliminary Findings from the Paramour “Pediatric Renal AMR Outcomes” Study
R. Zahr¹, D. Puliyanda², I. Ashoor³, N. Hayde⁴, S. Solomon⁵, R. Engen⁶, L. Harshman⁷, C. Peterson⁸, S. McEwen⁹, A. Jain¹⁰, R. Garro¹¹, A. Mansuri¹², M. Kallash¹³, K. Twombley¹⁴
¹Pediatrics, University of Tennessee Health Science Center, Memphis, TN, ²Cedars-Sinai Med Ctr, West Hollywood, CA, ³Pediatrics, Lousiana State University, New Orleans, LA, ⁴Montefiore Medical Center, Bronx, NY, ⁵The Children's Hospital at Montefiore, New York, NY, ⁶Pediatrics, University of Wisconsin Madison, Madison, WI, ⁷University of Iowa Children's Hospital, Iowa City, IA, ⁸University of Utah, Salt Lake City, UT, ⁹University of Minnesota, Minneapolis, MN, ¹⁰Pediatrics, Wayne State University, Troy, MI, ¹¹Emory University, Atlanta, GA, ¹²Pediatrics, Augusta University, Augusta, GA, ¹³Pediatrics, The Ohio State Univesrity, Columbus, OH, ¹⁴Medical University of South Carolina, Charleston, SC
*Purpose: Antibody mediated rejection (AMR) is a major cause of kidney allograft dysfunction leading to graft loss. There is a paucity of data regarding how…
2022 American Transplant Congress
Impact of Sarcopenia Using L3 and Thigh Skeletal Muscle Index on Clinical Outcomes in Liver Transplantation Recipient
M. Lim, J. Kim
Department of Surgery, Samsung Medical Cener, Seoul, Korea, Republic of
*Purpose: Sarcopenia is defined as loss of muscle mass and function. It has been reported as a significant risk factor for outcome after Liver transplantation…
2022 American Transplant Congress
The Sustained Impact of a Minimization Protocol on Peri-Operative Opioid Use in Kidney Transplantation
N. Patel, T. Carcella, J. Marable, V. Rohan, S. Bethi, P. Baliga, D. Dubay, J. N. Fleming, D. Taber
-MUSC, -Charleston, SC
*Purpose: Opioid use following kidney transplant (KTX) is associated with higher graft and patient loss. Thus, in 2019 we implemented an opioid minimization quality improvement…
2022 American Transplant Congress
Attitudes and Beliefs Towards Upper Extremity Donation in the United States
S. K. Rezwan, J. S. Puthumana, G. Brandacher, C. M. Cooney
Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: To date, upper extremity transplantation (UET) is the most frequently performed type of Vascularized Composite Allotransplantation (VCA). UET can most closely restore form, function,…
2022 American Transplant Congress
Utility of a Holistic Molecular Paradigm for Kidney Biopsy in the Clinic
S. Anand¹, J. Sanchez-Garcia¹, K. Qui², K. Pinney², A. Raza¹, T. Srinivas², D. Morris¹
¹Intermountain Medical Center, Murray, UT, ²CareDX, South San Francisco, CA
*Purpose: We report on the clinical utility of a serial dd-cfDNA (donor derived cell free DNA) monitoring coupled with Tissue Transcriptomics (Tr) and Histology (Hx)…
2022 American Transplant Congress
IL-15 Signaling is Required for the Maintenance of Tissue Resident Memory T Cells in Chronic Allograft Rejection
R. Tieu¹, Q. Zeng¹, D. Zhao¹, A. Williams¹, J. Yun Tso², F. Lakkis¹, J. Yun Tso²
¹Starzl Transplantation Institute, Pittsburgh, PA, ²JN Biosciences, Mountain View, CA
*Purpose: Currently, no immunotherapies have been clinically proven to prevent or treat chronic rejection. IL-15 is known to support memory T cell homeostasis. However, it…
2022 American Transplant Congress
Induction of Tacrolimus Clearance by Steroids Varies by Cyp3a5 Genotype in Kidney Transplant Recipients: A Drug-Drug-Gene Interaction
P. A. Jacobson¹, A. Saqr¹, M. Al-Kofahi¹, D. P. Schladt², W. Guan³, W. S. Oetting¹, R. Mannon⁴, C. R. Dorr⁵, R. P. Remmel¹, G. C. Onyeaghala⁶, B. Wu³, A. K. Israni⁷, A. Matas⁸
¹Univ of MN, College of Pharmacy, Minneapolis, MN, ²Hennepin Health Research Institute, Minneapolis, MN, ³Univ of MN, Biostatistics, Minneapolis, MN, ⁴Univ of Nebraska, Dept of Medicine, Omaha, NE, ⁵Hennepin Health Research Institute and Dept of Medicine, Minneapolis, MN, ⁶Hennepin Healthcare Research Institute, Minneapolis, MN, ⁷Hennepin Health Dept of Medicine and Univ of MN, Minneapolis, MN, ⁸University of MN, Dept of Surgery, Minneapolis, MN
*Purpose: Tacrolimus (TAC) is the primary immunosuppressant used in organ transplantation. TAC is a substrate for CYP3A4/5. These enzymes are inhibited or induced by multiple…
2022 American Transplant Congress
Optimal Intervention for Initial Treatment of Anastomotic Biliary Complications After Living Donor Liver Transplantation
M. Kim¹, S. Hong¹, H. Woo¹, J. Cho², J. Lee², K. Yoon¹, Y. Choi³, N. Yi⁴, K. Lee³, K. Suh¹
¹Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ²Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ³Seoul National University, Seoul, Korea, Republic of, ⁴Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Endoscopic retrograde cholangiopancreatography (ERCP) or percutaneous transhepatic biliary drainage (PTBD) may be performed in patients with anastomotic biliary complications (ABC) after living donor liver…
2022 American Transplant Congress
Development of a Comprehensive Banff Automation System for Kidney Allograft Precision Diagnostics
D. Yoo¹, J. Gueguen¹, G. Divard¹, M. Raynaud¹, V. Goutaudier¹, M. Rabant¹, M. Haas², M. Mengel³, O. Aubert¹, A. Loupy¹
¹Paris Transplant Group, Paris, France, ²Cedars-Sinai Medical Center, Dept. of Pathology, West Hollywood, CA, ³University of Alberta, Edmonton, AB, Canada
*Purpose: Since 1991, the Banff classification has been the gold standard for kidney allograft rejection diagnostics. However, with time, the classification has become complex with…
2022 American Transplant Congress
Metagenomic Next-Generation Sequencing Reveals the Profile of Viral Infections in Kidney Transplant Recipients During the Covid-19 Pandemic
X. Tian, W. Duan, C. Zhang, X. Wu, T. Yan
Henan Province People's Hospital, Zhengzhou, Henan Province, China
*Purpose: To study the clinical application of metagenomic next-generation sequencing (mNGS) in the detection of viral infections in kidney transplant recipients (KTRs) during the COVID-19…