Am J Transplant, Volume 22, Suppl 3 Archives - Page 23 of 190 - ATC Abstracts

2022 American Transplant Congress
Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury but Pharmacologic Inhibition of Estrogen Receptor Beta is Not
C. OBrien¹, P. Hernandez², S. Concors², Z. Wang¹, G. Ge¹, W. Hancock³, M. Levine²
¹Surgery, University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Renal Ischemia Reperfusion Injury (IRI) contributes substantially to delayed graft function (DGF) in kidney transplantation. Prior work by our group has shown lower rates…
2022 American Transplant Congress
Low-Dose Aspirin is More Critical Than Statins in Preventing Transplant Renal Artery Stenosis
B. Ji, X. Tian, G. Jing, T. Yan, X. Wu, G. Cao, C. Zhang
Urology, Henan Provincial People's Hospital, Zhengzhou, China
*Purpose: To explore the clinical value of low-dose aspirin (100mg) and statins (10 ~ 20mg) in the prevention of transplant renal artery stenosis (TRAS).*Methods: A…
2022 American Transplant Congress
Site-Directed Mutagenesis as a Tool to Investigate Immunogenicity of HLA Epitopes for Humoral Alloreactivity
C. H. Maguire¹, P. Crivello², A. Tambur¹
¹Northwestern University, Chicago, IL, ²University Hospital Essen, Essen, Germany
*Purpose: Molecular mismatch load (MML) analysis has been a proposed approach to assess donor/recipient compatibility in support of organ allocation algorithms. While conceptually appealing, MML…
2022 American Transplant Congress
Hold the Opioids Please: Long-Term Outcomes Following an Opioid Minimization Protocol in Kidney Transplantation
T. Carcella, N. Patel, J. Marable, J. Fleming, P. Baliga, D. Dubay, S. Bethi, D. Taber, V. Rohan
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use following kidney transplantation (KTX) is associated with an increased risk of graft loss and mortality. Opioid minimization strategies and protocols have demonstrated…
2022 American Transplant Congress
Intermediate Term Outcomes of SGLT2 Inhibitors Amongst Diabetic Kidney Transplant Recipients
C. Song¹, A. Brown², R. Winstead¹, S. Sterling¹, I. Yakubu², J. Christensen², G. Gupta²
¹Pharmacy, VCUHS, Richmond, VA, ²VCUHS, Richmond, VA
*Purpose: The use of Sodium Glucose Linked Transporter Inhibitors (SGLT-2i) among non-transplant diabetic patients with chronic kidney disease (CKD) has demonstrated reduced cardiovascular mortality, delayed…
2022 American Transplant Congress
Inhalation Alone versus Inhalation Plus Intravenous Colistin for Multidrug-Resistant Gram-Negative Bacterial Infection After Lung Transplantation
H. Kim¹, Y. Yang¹, A. Woo², S. Jeong³, S. Kim², J. Lee¹, M. Park², H. Paik¹
¹Department of thoracic and cardiovascular surgery, Yonsei University College of medicine, Seoul, Korea, Republic of, ²Division of Pulmonology, Department of Internal Medicine, Yonsei University College of medicine, Seoul, Korea, Republic of, ³Division of Infectious Disease, Department of Internal Medicine, Yonsei University College of medicine, Seoul, Korea, Republic of
*Purpose: After lung transplantation, patients are exposed to the risk of various infections accounting for morbidity and mortality. Multidrug-resistant gram-negative (MDR-GN) bacteria are emerging pathogen.…
2022 American Transplant Congress
EBV+ PTLD Tumor MicroRNAs Detected in Circulating Extracellular Vesicles Are Decreased in Pediatric Transplant Recipients with EBV+ PTLD
A. Sen¹, J. Enriquez¹, M. Rao¹, M. Glass¹, Y. Balachandran¹, S. Syed¹, C. Twist¹, K. Weinberg¹, S. D. Boyd¹, D. Bernstein¹, A. Trickey¹, D. Gratzinger¹, B. Tan¹, M. G. Lapasaran¹, M. A. Robien², M. Brown³, B. Armstrong⁴, M. Sever⁴, D. Desai⁵, G. Mazariegos⁶, C. Chin⁷, T. Fishbein⁸, R. S. Venick⁹, A. Tekin¹⁰, H. Zimmermann¹¹, R. U. Trappe¹², C. O. Esquivel¹, O. M. Martinez¹, S. M. Krams¹
¹Stanford U, Palo Alto, CA, ²NIH, Bethesda, MD, ³NIAID, Bethesda, MD, ⁴Rho, Durham, NC, ⁵UT Southwestern, Dallas, TX, ⁶Pittsburgh U, Pittsburgh, PA, ⁷CCHMC, Cincinnati, OH, ⁸Georgetown U, Washington, DC, ⁹UCLA, LA, CA, ¹⁰Miami U, Miami, FL, ¹¹DIAKO Ev. Diakonie-Krankenhaus, Bremen, Germany, ¹²Charité - Universitätsmedizin, Berlin, Germany
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Predisposing factors for PTLD include primary Epstein-Barr virus (EBV) infection in children,…
2022 American Transplant Congress
Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys
T. Hirose¹, G. Lassiter¹, D. Ma¹, A. D'Attilio¹, I. Rosales¹, D. Cloonan¹, R. Matheson¹, R. Colvin¹, W. Qin², Y. Kan², J. Layer², R. Anand², V. Paragas², L. Queroz², X. Tan², I. Kohnle², K. Stiede², K. Hall², M. Youd², M. Curtis², J. Markmann¹, T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²eGenesis Inc, Cambridge, MA
*Purpose: Pigs with deletion of 3 carbohydrate xenoantigens (triple knock-out, TKO) are expected to be optimal donors for human xenotransplantation. We have previously shown that…
2022 American Transplant Congress
Acute Graft versus Host Disease (AGVHD) Related to Solid Organ Transplant (SOT) – A Fatal Complication
H. Shaikh¹, J. Awosika¹, B. Barakoti¹, B. Hambley¹, C. Alquist²
¹University of Cincinnati Medical Center, Cincinnati, OH, ²Hoxworth Blood Center, Cincinnati, OH
*Purpose: This case series highlights our institution's experience with solid-organ transplant (SOT) associated acute graft versus host disease (aGVHD), a rare and deadly complication of…
2022 American Transplant Congress
Post-Kidney Donation Pregnancy Complications and Long-Term Outcomes
E. F. Palzer¹, E. S. Helgeson¹, M. Evans², D. Vock¹, A. Matas³
¹Biostatistics, University of Minnesota, Minneapolis, MN, ²Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, ³Surgery, University of Minnesota Medical School, Minneapolis, MN
*Purpose: In the general population, pregnancy complications are associated with long-term maternal risk. Kidney donors with postdonation pregnancies have increased risk of gestational HTN and…