2022 American Transplant Congress
Donor Kidneys from Communities with Higher Deprivation Are Significantly More Likely to be Discarded
1Cleveland Clinic, Cleveland, OH, 2Columbia University, New York, NY
*Purpose: The proportion of kidneys procured for the purpose of transplantation but ultimately discarded exceeds 20% in the US. Factors associated with deceased donor kidney…2022 American Transplant Congress
A Comparison of Self-Reported Physical Function to In-Person Frailty Assessments for the Prediction of Rehospitalizations After Kidney Transplantation
*Purpose: Rehospitalizations are common after kidney transplantation (KT) and associated with increased cost, allograft failure, and death. Physical frailty as defined by Fried criteria has…2022 American Transplant Congress
Regulatory Gene Pathways Are Upregulated in Heart Transplant Biopsies with Quilty Lesions
Pathology, UTSW Medical Ctr, Dallas, TX
*Purpose: Quilty lesions (QL) are commonly sub-endocardial lymphoid aggregates found in biopsies from heart transplants. Their appearance and presence in the cardiac tissue is still…2022 American Transplant Congress
Single-Cell RNA Sequencing Highlights the Role of Epithelial-Immune Dual Feature of Proximal Tubule Cells in BK Virus Nephropathy
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
*Purpose: BK virus nephropathy (BKVN) may cause renal allograft dysfunction and failure. However, a specific antiviral agent for BK virus does not exist. Increasing evidence…2022 American Transplant Congress
Final Report of the Use of α-Lipoic Acid in Liver Transplantation to Prevent Ischemia Reperfusion Injury
1Hospital Italiano, Buenos Aires, Argentina, 2CEFYBO, Buenos Aires, Argentina
*Purpose: The ischemia and reperfusion injury contributs to grafts deterioration and adverse post-transplant outcomes. The aim of the present study was to evaluate the safety…2022 American Transplant Congress
Autoimmune Responses to DNA Topoisomerase I Exacerbate Renal Allograft Injury
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Immune responses to self antigens develop following organ transplantation. Multiple studies describe correlations between pre-existing or de novo autoimmune responses and poor transplant outcome.…2022 American Transplant Congress
A Single-Centre Study on the Diagnosis and Management of Transplant Ureteric Strictures: An 11 Year Experience
*Purpose: The optimal management of transplant ureteric stricture is unclear. This study presents a single-centre's 11-year experience of the diagnosis and management of these cases.*Methods:…2022 American Transplant Congress
Race Misclassification in Kidney Transplantation Research
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Recently, the use of socially constructed “race” in kidney disease research has received national attention partly because of the research bias created when race…2022 American Transplant Congress
Hypomethylated Regulatory Regions in Immune Signaling Genes Characterize Rejection Prone Pediatric Liver Transplant (LT) Recipients
*Purpose: Transcriptional regulation of LT rejection may reveal novel predictive and therapeutic targets. To identify signaling pathways which are differentially regulated by DNA methylation in…2022 American Transplant Congress
Transbronchial Cryobiopsy vs Conventional Forceps Biopsy in Lung Transplant Recipients Multicenter Study
*Purpose: Transbronchial biopsy is considered the gold standard in the diagnosis of acute cellular rejection after lung transplantation. There still remains the discussion in conventional…
American Transplant Congress abstracts