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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    COVID Infection Among Kidney Transplant Recipient During the Era of COVID Vaccination: Management Outcomes

    G. Uehara, K. Soliman, V. Rao, M. Casey, D. Taber, M. Posadas Salas

    Nephrology, Medical University of South Carolina, Charleston, SC

    *Purpose: COVID pandemic has posed a significant challenge among kidney transplant recipients (KTR) due to their immunocompromised state. There is uncertainty on immunosuppression (IS) management…
  • 2022 American Transplant Congress

    Safety and Immunogenicity of BNT-162b2 versus Chadox1 Vaccine in Solid Organ Transplant Recipients: Prospective Study

    A. Ajlan1, T. Ali2, H. Aleid2, K. Almeshari2, M. Alkaff3, S. Althuwaidi4, L. Fajji2, A. Alali5, D. Halabi6, A. Ullah7, K. H. Marquez8, B. Elmikkaoui9, A. Alrajhi10, A. Zidan11, E. Albogumi.12, K. Bzeizi13, R. Almaghrabi14, E. DeVol15, M. Al-Awwami,16, S. Alghamdi13, P. Broering2

    1Pharmaceutical Care Division - Organ Transplant Centre of Excellence, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riaydh, Saudi Arabia, 2Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 3Medical Laboratory, KFSHRC, Riaydh, Saudi Arabia, 4Medical Microbiology, KFSHRC, Riaydh, Saudi Arabia, 5Transplant Coordination Team - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 6Transplant Coordination Team - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 7Kidney & Pancreas Health Centre, KFSHRC, Riaydh, Saudi Arabia, 8Analytics Data Centre - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 9Data Management - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 10Infectious Diseases - Medicine Department, KFSHRC, Riaydh, Saudi Arabia, 11Abdominal Transplant & Hepatobiliary Surgery Centre, KFSHRC, Riaydh, Saudi Arabia, 12Data Management. - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 13Liver & Small Bowel Health Centre, KFSHRC, Riaydh, Saudi Arabia, 14Infectious Diseases - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 15Biostatistics, Epidemiology &Scientific Computing, KFSHRC, Riaydh, Saudi Arabia, 16Histocompatibility and Immunogenetics Laboratory Kidney & Pa - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia

    *Purpose: Data showed seroconversion after different SARS-CoV-2 vaccination platforms might yield diminished response in transplant recipients. However, it is unknown whether different vaccination platforms could…
  • 2022 American Transplant Congress

    Viral-Specific Cytotoxic T-Cell Responses in Hla-Sensitized Kidney Transplant Patients Maintained on Everolimus and Low Dose Tacrolimus

    R. Zhang1, S. Ge1, M. Chu1, J. Kahwaji2, A. Karasyov1, D. Lovato1, A. Vo2, J. Choi2, M. Toyoda1, S. Jordan2

    1Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Post-transplant immunosuppression with “everolimus + reduced dose tacrolimus” (Ev + Taclow) is reported to reduce the risk of viral infections compared to standard doses…
  • 2022 American Transplant Congress

    Outcomes in Renal Transplant Recipients Receiving Pre-Transplant Financial Assistance Through the American Kidney Fund

    H. Roppo1, P. Klem1, B. Crowther1, E. Sartain1, K. Schoeppler1, P. T. Kennealey2, B. Kaplan3

    1Department of Pharmacy, University of Colorado Hospital, Aurora, CO, 2Department of Surgery, University of Colorado Hospital, Aurora, CO, 3Department of Renal Med Diseases/Hypertension, University of Colorado Hospital, Aurora, CO

    *Purpose: Pre-transplant financial assistance for insurance premiums is available for eligible patients through the American Kidney Fund (AKF), but this funding ends within the first…
  • 2022 American Transplant Congress

    Characterization of Activated Islet Proliferating Cells (AIPCs) During Maturation to Pseudo-Islets

    Y. Garciafigueroa, J. B. Pollett, N. Thai, R. Bottino

    Imagine Pharma, Pittsburgh, PA

    *Purpose: We have previously described a novel population of cells developed from human islets called AIPCs (Activated Islet Proliferating Cells). AIPCs co-express CD133, glucagon and…
  • 2022 American Transplant Congress

    Safety and Efficacy of Darbepoetin Alfa Dosing Strategies in Renal Transplant Recipients

    J. A. Solis, A. Dao, T. Sam, T. Ma, A. F. Yango, B. V. Fischbach, N. Wilson

    Baylor University Medical Center, Dallas, TX

    *Purpose: Post-transplant anemia (PTA) is a common phenomenon in renal transplant recipients (RTR). There are currently no consensus guidelines for PTA, however patients are commonly…
  • 2022 American Transplant Congress

    Elevated Donor-Derived Cell-Free DNA (dd-cfDNA) in the Early Post-Transplant Period is Associated with an Increased Incidence of Adverse Clinical Outcomes in Kidney Transplant Recipients

    D. Wojciechowski1, A. Patel2, S. Anand3, J. Klein4, A. Paramesh5, P. Sood6, G. Shekhtman7, N. Agrawal7, M. Fei7, K. Qu7, D. C. Brennan8

    1University of Texas, Southwestern, Dallas, TX, 2Saint Barnabas Medical Center, Livingston, NJ, 3Intermountain Healthcare, Murray, UT, 4University of Kansas Medical Center, Kansas City, KS, 5Tulane University School of Medicine, New Orleans, LA, 6University of Pittsburgh Medical Center, Pittsburgh, PA, 7CareDx, Brisbane, CA, 8Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Early post-transplant elevations in dd-cfDNA, even in the absence of histologic rejection or other overt pathology, have been suggested to carry a risk of…
  • 2022 American Transplant Congress

    Brain Death as a Novel Preclinical Human Model for the Advancement of Medicine

    C. Killian1, B. Orandi1, D. Anderson1, V. Kumar2, K. Stegner1, N. Budd1, S. Macedon1, A. Shunk3, P. Porrett1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham Hospital, Birmingham, AL, 3Legacy of Hope, Birmingham, AL

    *Purpose: For interventions that lack US Food and Drug Administration approval, testing is limited and relies on preclinical animal models to determine safety and efficacy.…
  • 2022 American Transplant Congress

    The Role of Gastrointestinal Pathogen PCR Testing in Liver Transplant Recipients Hospitalized with Diarrheal Illness

    C. K. Ching1, Y. R. Nobel2, M. R. Pereira3, E. C. Verna4

    1Department of Medicine, Columbia University Medical Center, New York, NY, 2Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY, 3Division of Infectious Diseases, Columbia University Medical Center, New York, NY, 4Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY

    *Purpose: Diarrhea is a common complication among liver transplant (LT) recipients and can result in significant morbidity. The development of PCR-based multiplex gastrointestinal (GI) pathogen…
  • 2022 American Transplant Congress

    Kidney, Lung and Liver Transplant Patients’, Kidney Transplant Candidates’ and Living Donors’ Perspectives on the Role of Patients’ Stories and Creative Writing in Transplantation: An Exploratory Study

    L. Laneuville1, F. Ballesteros Gallego2, A. Affdal2, B. Gagnon-Chainey3, L. Brassard2, P. Millot3, S. Harel3, C. Mavrikakis3, M. Malo3, M. Fortin2

    1McGill University, Montreal, QC, Canada, 2CRCHUM, Montreal, QC, Canada, 3University of Montreal, Montreal, QC, Canada

    *Purpose: Organ transplantation is associated with medical, psychological and existential challenges for patients. Patients’ experiential knowledge can help other patients facing these challenges. Patients’ stories…
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