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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pediatric Acute Liver Failure: Patient Factors Associated with Higher Mortality

    J. Ascher Bartlett1, C. Weaver1, S. Barhouma2, L. Houshmand2, B. Rocque2, K. Etesami2, R. Kohli1, J. Emamaullee2

    1Children's Hospital Los Angeles, Los Angeles, CA, 2University of Southern California, Los Angeles, CA

    *Purpose: Pediatric acute liver failure (PALF) is characterized by sudden onset deteriorating liver function, progressive coagulopathy, and hepatic encephalopathy in previously healthy children. The clinical…
  • 2022 American Transplant Congress

    Incidence and Laterality of Pulmonary Emboli in Single Lung Transplant Recipients

    F. Pyarali1, J. Thomas2, A. Peiris2, R. Rampolla1

    1Department of Pulmonary and Critical Care, Cedars Sinai Medical Center, Los Angeles, CA, 2Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Lung transplantation surgery increases the risk of pulmonary embolism (PE), with an incidence described between 6% to 27%, based on data from 15 years…
  • 2022 American Transplant Congress

    Temporal Trends in Utilization, Discard, and Outcomes for Extended Criteria Donor Lungs

    A. Hallett1, L. Zeiser1, W. Lightle2, J. Ruck1, J. Alejo1, A. Massie1, D. Segev1

    1Johns Hopkins, Baltimore, MD, 2Baylor, Houston, TX

    *Purpose: Extended criteria donor lungs (ECDL) are defined as those failing to meet ≥1 standard donor criteria (P/F > 300, age < 55, smoking <…
  • 2022 American Transplant Congress

    Dd-cfdna Correlates With Acute Rejection In The Setting Of Bk Viremia After Kidney Transplantation

    N. M. Ali1, J. Miles2, V. Tatapudi1, R. Chand1, R. Montgomery1

    1NYU Langone Transplant Institute, New York, NY, 2CareDx, Brooklyn, NY

    *Purpose: BK virus reactivation is common among kidney transplant recipients (KTRs) and is a risk factor for allograft loss. Currently, there is no clearly established…
  • 2022 American Transplant Congress

    Early Clinical Complications Following HLA-Incompatible Living Donor Kidney Transplantation

    J. D. Motter1, K. Jackson1, A. Massie1, J. Garonzik-Wang2, D. Segev1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin-Madison, Madison, WI

    *Purpose: Incompatible living donor kidney transplant recipients (ILDKTr) require desensitization to facilitate transplantation across donor-specific antibody (DSA); however, this substantial upfront immunosuppression may result in…
  • 2022 American Transplant Congress

    Conversion to Belatacept for Calcineurin Inhibitor Toxicities

    S. S. Patel, P. Jadav, M. Sekulic, S. Kudose, I. Batal, S. Mohan, R. Crew

    Columbia University Medical Center, New York, NY

    *Purpose: Calcineurin inhibitors (CNIs) have improved renal transplant (RTx) outcomes but are associated with significant toxicities. Belatacept provides better long-term outcomes than cyclosporine, has less…
  • 2022 American Transplant Congress

    Outcomes of Primary Simultaneous Pancreas-Kidney Transplants by Induction Agent in the United States

    A. Cerise1, T. Shaker1, K. Ramanathan1, S. Jackson2, R. Kandaswamy1, S. Riad3

    1Surgery, University of Minnesota, Minneapolis, MN, 2Analytics, MHealth-Fairview, Minneapolis, MN, 3Medicine, University of Minnesota, Minneapolis, MN

    *Purpose: Induction immunosuppression choice for simultaneous pancreas-kidney (SPK) transplants varies widely in the United States. We examined the association between induction agents and outcomes of…
  • 2022 American Transplant Congress

    Navigating the Ethics of Transplant Research Involving Newly Deceased

    B. Parent1, T. Schiff2, E. Weldon3, N. Lawson4, S. Mehta5, R. A. Montgomery6

    1Medical Ethics, NYU Grossman School of Medicine, New York, NY, 2Medical Ethics, NYU School of Medicine, New York, NY, 3NYU Langone Health-Transplant Institute, New York, NY, 4NYU Langone Transplant Institute, New York, NY, 5New York University Langone Transplant Institute, New York, NY, 6NYU Langone, New York, NY

    *Purpose: The most promising innovations for overcoming the organ shortage include novel organ sources such as xenotransplant and bioengineered organs. Studying these organs in mechanically…
  • 2022 American Transplant Congress

    External Validation of the Abbreviated Ibox Scoring System at One-Year Post Kidney Transplant as a Surrogate Endpoint for Death-Censored Graft Survival

    A. Klein1, L. Kosinski2, R. Muse2, A. Loupy3, O. Aubert3, G. Divard3, M. Stegall4, I. Helanterä5, W. E. Fitzsimmons1, I. O'Doherty1

    1Transplant Therapeutics Consortium, Critical Path Institute, Tucson, AZ, 2Critical Path Institute, Tucson, AZ, 3Paris Transplant Group, Paris, France, 4Mayo Clinic, Rochester, MN, 5Helsinki University Hospital, Helsinki, Finland

    *Purpose: The Transplant Therapeutics Consortium seeks to translate the iBox from Loupy et al., 2019 into a surrogate endpoint for five-year death-censored graft survival after…
  • 2022 American Transplant Congress

    Performance of Race-Independent GFR Estimating Formulas, CKD-EPI2021 and NMR-GFR Post Kidney Transplantation

    E. Schiffer1, F. Stammler2, M. Grassi2, E. Schiffer2

    1Clinical Research, numares Group Corporation, Boston, MA, 2Research and Development, numares AG, Regensburg, Germany

    *Purpose: Progressive GFR decline post kidney transplantation is a general problem that requires accurate assessment of GFR for clinical decision making. The gold-standard radiotracer determined…
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