2022 American Transplant Congress
Racial Hot Spots of Non-Preemptive Kidney Transplant Wait Listing, 2010-2020
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH
*Purpose: Waitlisting kidney transplant patients before dialysis results in better long-term outcomes. Substantial racial disparities exist for preemptive waitlisting and identification of areas where race…2022 American Transplant Congress
Development of a Portable Device to Quantify Hepatic Steatosis in Donated Livers Using an AI Algorithm
1Computer Science, Stanford, Stanford, CA, 2Surgery, Stanford, Stanford, CA
*Purpose: An accurate estimation of liver fat content is necessary to predict how a donor liver will function after transplantation. This can be challenging at…2022 American Transplant Congress
Angiotensin II-Regulated Proteins Production by Pulmonary Macrophages in Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD), characterized by fibrosis, is the most important cause of mortality after lung transplantation. CLAD mechanisms remain poorly understood and…2022 American Transplant Congress
Combined Metagenomic Viral Detection and Donor-Derived Cell-Free DNA Quantification for Solid Organ Transplant Recipients
1Eurofins Viracor, Lees Summit, MO, 2Northwestern University, Chicago, IL
*Purpose: Solid organ transplant recipients are predisposed to opportunistic infections, and current viral diagnostic methods focus on sensitive detection of single pathogens by qPCR. However,…2022 American Transplant Congress
Fibroblastic Reticular Cell Lama4 Regulates T Cell Migration to Lymph Nodes and Adaptive Immunity
1Surgery, UMB, Baltimore, MD, 2Harvard University, Boston, MA
*Purpose: Lymph node (LN) stromal laminin α4 (Lama4) is associated with tolerance. We hypothesized that fibroblastic reticular cell (FRC) derived Lama4 contributes to a tolerogenic…2022 American Transplant Congress
Brief Human IL-2 Mutein Therapy Induces Foxp3+ T-Regulatory Cell Expansion and Donor-Specific Allograft Tolerance
*Purpose: New therapeutic approaches to the management of transplant recipients are warranted in efforts to improve outcomes.*Methods: We have engineered a modified human IL-2 protein…2022 American Transplant Congress
Trends on Organ Transplantation and Donation Based on Public Sentiments Expressed in Social Media Comments in Korea: Text Mining Analysis
Department of Surgery, Kyung Hee University, College of Medicine, Seoul, Korea, Republic of
*Purpose: The shortage of deceased organ donation is a challenge for most countries. In the media era, the role of social media is becoming important…2022 American Transplant Congress
Donor-Specificb Cell Dysfunction and Suppressive Ability Are Differentially Induced in Cob-Mediated Transplantation Tolerance
*Purpose: B cells in mice tolerized to fully mismatched heart allografts with anti-CD154+donor spleen cells (CoB) are intrinsically dysfunctional and unable to differentiate into germinal…2022 American Transplant Congress
Metastatic BK Virus-Associated Urothelial Carcinoma Originating in Renal Allograft
1Pathology, UT Southwestern, Dallas, TX, 2Internal Medicine, UT Southwestern, Dallas, TX
*Purpose: Cases of urinary tract carcinoma associated with BK virus have been reported in kidney transplant recipients; therefore, we postulate that BK virus may play…2022 American Transplant Congress
Liver Transplantation is Beneficial Regardless of Cirrhosis Stage or Acute-on-Chronic Liver Failure Grade: A Single-Center Experience
*Purpose: Liver transplantation for the most critically ill remains controversial; however, it is currently the only curative treatment option. The aim of this study was…
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