2022 American Transplant Congress
Triple-Knockout Pig Red Blood Cells as Potential Sources for Blood Transfusion in Alloimmunized Patients with Sickle Cell Disease
*Purpose: Blood transfusion remains important in the treatment of patients with sickle cell disease (SCD). However, alloimmunization after multiple blood transfusions is associated with patient…2022 American Transplant Congress
Increased Baboon Chimerism After Peripheral Blood Stem Cell Infusion from a Novel GalTKO Pig with Functional Humanized Il-3 Receptor
Columbia University Irving Medical Center, New York, NY
*Purpose: The purpose of this study was to investigate whether expression of a humanized IL-3 receptor (hCD123+hCD131) transgene in a GalTKO pig would improve levels…2022 American Transplant Congress
Implementation of Infectious Disease Surveillance in Recently Deceased Human Xenograft Study
NYU Langone Transplant Institute, New York, NY
*Purpose: Xenotransplantation is a promising solution for the ongoing organ shortage but has been slow to develop because of both immunological challenges and potential risk…2022 American Transplant Congress
RBBP7 as a Novel Biomarker for the Molecular Diagnosis of BK Virus-Associated Nephropathy
Department of Urology, Beijing Chaoyang Hospital, Beijing, China
*Purpose: BK virus-associated nephropathy (BKVN) remains a major infectious complication of kidney transplantation, and its histologic appearance can mimic rejection, leading to a diagnostic dilemma…2022 American Transplant Congress
Cost-Effectiveness of an Intra-Operative Renal Allograft Cooling Device
1University of California, San Francisco, San Francisco, CA, 2Stanford, Palo Alto, CA
*Purpose: Existing literature shows intra-operative cooling of a renal allograft during anastomosis reduces the incidence of delayed graft function in deceased donor kidney transplant recipients…2022 American Transplant Congress
Letermovir for Prophylaxis of Cytomegalovirus After Solid Organ Transplantation: A Single-Center, Observational Study
*Purpose: Cytomegalovirus (CMV) infections cause significant complications post-transplant; however, prophylactic medications are often limited by toxicities. Letermovir is a novel terminase inhibitor specific to CMV…2022 American Transplant Congress
Low Fixed Tacrolimus Starting Dose and the Correlation with Renal Allograft Rejection
David Geffen School of Medicine, Los Angeles, CA
*Purpose: Achieving a tacrolimus therapeutic trough concentration (C0) by post-operative day (POD) 3-7 has been associated with a reduced risk for rejection. Although FDA prescribing…2022 American Transplant Congress
Evaluation of Renal Function After Donation in Living Marginal Kidney Donor
*Purpose: Chronic kidney-donor shortage is major concern in Japan where more than 90% of recipients received kidneys from living donor as kidney transplantation from deceased…2022 American Transplant Congress
Discovery of Risk Factor Control Targets Using Machine Learning and Network Analysis for One-Year Renal Allograft Dysfunction
*Purpose: Early identification of graft loss risk and timely therapeutic intervention are crucial for preventing late renal allograft failure and improving long-term graft function. This…2022 American Transplant Congress
Humoral and Cellular Immunity 6 Months After SARS-CoV-2 Infection in Solid-Organ Transplant Recipients
*Purpose: The purpose of this study was to evaluate long term humoral and cellular immunity generated following SARS-CoV-2 infection in solid organ transplant recipients (SOTR).*Methods:…
American Transplant Congress abstracts