2022 American Transplant Congress
Is Pathologic AMR Grading Scale Associated with the Presence of Donor-Specific Antibodies?
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Antibody-mediated rejection (AMR) has been defined by an expert pathology group in 2011 which resulted in the ISHLT pathologic AMR (pAMR) grading scale. The…2022 American Transplant Congress
Bacterial Infections After Kidney Transplant Before and After the COVID-19 Pandemic
*Purpose: Infectious complications are a major cause of mortality and morbidity after kidney transplantation. During the COVID-19 pandemia there were several changes in the management…2022 American Transplant Congress
Comparison of Cephalexin and Ciprofloxacin Prophylaxis for Urinary Tract Infection in Kidney Transplant Recipients
Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Compare efficacy and safety outcomes of patients (pts) that received alternative agents as prophylaxis (ppx) for urinary tract infection (UTI) after kidney transplant (KT)…2022 American Transplant Congress
Outcome of Heart Transplantation After Pseudomonas Left Ventricular Assist Device Infection
*Purpose: Pseudomonas aeruginosa (PA) is the most common gram-negative bacteria to cause left ventricular assist device (LVAD) infection. Management is difficult given limited oral antibiotic…2022 American Transplant Congress
Tacrolimus Induces Dedifferentiation of Pancreatic Beta Cells by Inhibition of Calcineurin/NFATc2 and Islet Cell Differentiation Genes
*Purpose: Tacrolimus (FK506) is a potent immunosuppressant widely used for solid organ transplantation to prevent lymphokine gene expression by inhibiting calcineurin (CN) and its downstream…2022 American Transplant Congress
The Role of LAG3 in Antibody Responses to Kidney Transplantation
*Purpose: The functions of coinhibitory receptor lymphocyte activation gene-3 (LAG3) in T cells are well studied, however its role in humoral immune responses remains poorly…2022 American Transplant Congress
TCMR in Late Kidney Transplant Biopsies Shows Less Molecular TCMR Activity and More Fibrosis Despite Persistence of Tubulitis and Interstitial Infiltrate
1Alberta Transplant Applied Genomics Centre, Edmonton AB, AB, Canada, 2., ., AB, Canada
*Purpose: We studied the relationship between time post-transplant and molecular T cell-mediated rejection (TCMR) activity in a population of indication kidney transplant biopsies.*Methods: Updated rejection-based…2022 American Transplant Congress
Factor V Leiden Heterozygosity and Live Donor Liver Donation – A Single Center Analysis
Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Living donor liver transplantation (LDLT) accounts for only a small percentage (< 6%) of all liver transplants performed for adult recipients in the western…2022 American Transplant Congress
Organ Transplant Outcomes from Donors with Positive SARS-CoV-2 PCRs in New York: A Case Series
*Purpose: Rapid evolution of the SARS-CoV-2 pandemic over the past 24 months has demanded agility in managing selection criteria for deceased organ donors, with the…2022 American Transplant Congress
Survey of Current Transplant Center Practices Regarding Covid-19 Vaccine Mandates in the United States
*Purpose: We surveyed current policies of transplant centers regarding a COVID-19 vaccine mandate, and rationales for or against a mandate policy.*Methods: An electronic survey was…