2022 American Transplant Congress
Development and Validation of a Machine Learning Based Virtual Biopsy System in Kidney Transplant Patients
*Purpose: In kidney TX, day-zero biopsies are used to assess organ quality and discriminate lesions inherited from the donor or acquired after transplantation. However, many…2022 American Transplant Congress
Incidence and Outcomes of Fever of Unknown Origin After Kidney Transplant in the Modern Era
University of Wisconsin Health, Madison, WI
*Purpose: Fever is common in kidney transplant recipients (KTRs). If an etiology is not readily apparent, a patient can be classified as having a fever…2022 American Transplant Congress
Hepatocyte Notch1 Regulates Autophagy/DR5 Axis and Inhibits Cell Death in Mouse and Human Liver Transplantation
*Purpose: Liver ischemia-reperfusion injury (IRI) is a major risk factor of early graft dysfunction and predisposes to rejection in orthotopic liver transplantation (OLT). Although Notch1…2022 American Transplant Congress
A Novel IL-2 Mutein Selectively Expands Regulatory T Cells and Prolongs Skin Graft Survival
*Purpose: Promoting immune regulation through expansion of regulatory T cell (Treg) may allow immunosuppression minimization and improve long-term graft outcomes. Low-dose IL-2 is known to…2022 American Transplant Congress
Conversion to Everolimus-Based Immunosuppression Regimen with Calcineurin Inhibitor Reduction Ameliorates Histological Damage in Kidney Transplant Recipients with Calcineurin Inhibitor-Induced Nephrotoxicity
Hokkaido University Hospital, Sapporo, Japan
*Purpose: In the last two decades, the short-term results for kidney transplantation (KTX) have improved owing to the use of calcineurin inhibitors (CNIs). However, long-term…2022 American Transplant Congress
Effect of Covid-19 Diagnosis on Organ Donation and Transplantation
*Purpose: The coronavirus disease 2019 (COVID-19) pandemic has challenged many aspects of healthcare, including organ donation and transplantation. The purpose of this study is to…2022 American Transplant Congress
Cold Pulsatile Perfusion Preservation of Deceased Donor Kidneys Did Not Improve Delayed Graft Function Rates in Most Transplants Due to Longer Cold Ischemia Times Offsetting Much of the Benefit, Analysis of SRTR Database
Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine the impact of cold pulsatile perfusion preservation (CPPP) on delayed graft function (DGF) in a national cohort of US kidney transplants as…2022 American Transplant Congress
Management of Brain-Dead Organ Donors by a Dedicated ICU Team Improves Organ Yield
*Purpose: Management of brain-dead (BD) donors can be challenging in hospitals with limited ICU bed availability, lack of accessible diagnostic capabilities, and a culture that…2022 American Transplant Congress
Prediction of Delayed Graft Function After Deceased Donor Kidney Transplantation Using Machine Learning and Sequential Donor Data
*Purpose: Delayed graft function (DGF) has been associated with adverse kidney transplant outcomes. Accurate prediction of DGF before surgery will help select organs and candidates…2022 American Transplant Congress
Ficoll-Based Isolation Alters the Immunogenicity of Islets That Leads to Enhanced Rejection in Allogeneic Hosts
*Purpose: The purification of pancreatic islets has long relied on the time-consuming density gradient separation method. We herein report a filtration method as an efficient,…
American Transplant Congress abstracts