Am J Transplant, Volume 22, Suppl 3 Archives - Page 187 of 190 - ATC Abstracts

2022 American Transplant Congress
Characterization Of Local Antibody Responses In Human Cardiac Allograft Vasculopathy
S. B. See¹, L. J. Stanton¹, P. Roy¹, S. Mashiko¹, E. R. Vasilescu², C. C. Marboe², M. Szabolcs², M. V. Habal³, M. Farr³, S. Restaino³, Y. Naka⁴, D. M. Mancini⁵, J. C. Madsen⁶, R. G. King⁷, E. P. Kransdorf⁸, E. Zorn¹
¹CCTI, Columbia University Irving Medical Center, New York, NY, ²Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, ³Medicine, Columbia University Irving Medical Center, New York, NY, ⁴Surgery, Columbia University Irving Medical Center, New York, NY, ⁵Cardiology, Icahn School of Medicine, New York, NY, ⁶CTS, Massachusetts General Hospital, Boston, MA, ⁷Microbiology, University of Alabama, Birmingham, AL, ⁸Cedars-Sinai Heart Institute, Los Angeles, CA
*Purpose: Cardiac allograft vasculopathy (CAV) is the leading cause of heart graft recipient mortality after five years post-transplant. A major hurdle to improving outcomes is…
2022 American Transplant Congress
Immunotherapy Before Solid Organ Transplantation: An International Transplant Community-Focused Survey
T. Ivanics¹, M. P. Claasen¹, D. Al-Adra², G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada
*Purpose: The use of immunotherapy for cancer has increased and is expected to continue to grow. The outcomes after solid organ transplantation (SOT) in patients…
2022 American Transplant Congress
Donor Macrophage Depletion Improves Kidney Graft Function Despite Long Cold Ischemia
C. Jordan¹, A. Dangi², X. Luo¹
¹Duke University School of Medicine, Durham, NC, ²Medicine, Duke University, Durham, NC
*Purpose: Prolonged cold ischemia is a known risk factor for delayed graft function and poorer outcomes after kidney transplantation. Overcoming this obstacle is key to…
2022 American Transplant Congress
Influence of Regulatory B Cells on B Cells
Q. Fu¹, K. M. Lee², K. Deng², D. Agarwal¹, R. Matheson³, T. Press¹, J. Lei⁴, H. Yang⁵, C. LeGuern², S. Deng⁵, J. F. Markmann²
¹Center for Transplant Science, MGH, Boston, MA, ²Massachusetts General Hospital, Boston, MA, ³Transplantation Surgery Research, Massachusetts General Hospital, Boston, MA, ⁴Surgery, Mass General, Boston, MA, ⁵Sichuan Provincial People's Hospital, University of Electronic Sciences and Technology of China, Chengdu, China
*Purpose: Our previous study showed that Bregs-TLR, one type of previously studied Breg expanded in vitro, are capable of suppressing naïve B cell proliferation in…
2022 American Transplant Congress
NecroX-7 Ameliorate FK506-Induced Nephrotoxicity in LLC-PK1 Cells (Pig Kidney Epithelial Cells)
H. J. Jang
Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea, Republic of
*Purpose: Tacrolimus (FK506) is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and…
2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
K. E. Karakasi¹, G. Katsanos², I. Karolos³, V. Tsioukas³, G. Tsoulfas⁴
¹University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, ²Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, ³School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, ⁴University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
2022 American Transplant Congress
The Unique Course of dd-cfDNA After Lung Transplant
D. Levine¹, C. Giner¹, C. Pham², R. Woodward³, A. Roux⁴
¹University of Texas Health System San Antonio, San Antonio, TX, ²CareDX, South San Francisco, CA, ³CareDx, South San Francisco, CA, ⁴Pneumology, Adult CF Center and Lung Transplantation Department, Foch Hospital, Suresnes, France
*Purpose: The time necessary for dd-cfDNA to reach baseline levels following transplantation has been reported in kidney, heart, and liver as 14-21 days. We explored…
2022 American Transplant Congress
CD31⁺ Extracellular Vesicles in Ex Vivo Lung Perfusion Are Associated with Unsuitability for Transplant
G. C. Madu¹, S. Moshkelgosha², A. Chruscinski³, A. Sage², M. Cypel², S. Keshavjee², S. Juvet²
¹Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada, ²University Health Network, Toronto, ON, Canada, ³Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada
*Purpose: Primary graft dysfunction (PGD) is an important cause of morbidity and mortality following lung transplantation and results in part from injuries sustained in the…
2022 American Transplant Congress
Dynamic Changes of Serum Soluble B Cell Activating Factor in Kidney Transplant with De Novo Donor Specific Antibody
S. Wu¹, X. Su¹, Y. Gao¹, Y. Wei¹, Q. Ye¹, M. Huang², Y. Chen¹, J. Wang¹, Q. Zhang³, Q. Fu¹, J. Li², H. Huang², B. Xu², H. Zhang¹, L. Liu², C. Wang²
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, ²The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, ³Charité - Universitätsmedizin Berlin, Berlin, Germany
*Purpose: De novo donor specific antibody (dnDSA) plays a crucial role in the development of antibody mediated rejection (ABMR) and is correlated to the worse…
2022 American Transplant Congress
Integrated Alcohol Use Disorder Clinic as a Strategy to Reduce Alcohol Relapse After Early Liver Transplantation in Patients with Alcohol Related Liver Disease
R. Z. Syed¹, C. Albers², N. Kemmer², V. Subramanian², C. Machado-Denis¹, K. Dhanireddy²
¹Hepatology and Liver Transplantation, Tampa General Hospital, Tampa, FL, ²Tampa General Hospital, Tampa, FL
*Purpose: In recent years, for patients with Alcohol related Liver Disease (ALD), there has been a trend towards early Liver Transplantation (LT) rather than waiting…