Am J Transplant, Volume 22, Suppl 3 Archives - Page 186 of 190 - ATC Abstracts

2022 American Transplant Congress
Intensive Antimetabolite Reduction is Not Associated with Increased Risk of Biopsy-Proven Acute Rejection in Kidney Transplant Recipients with BK Virus Infection; a Single Center Experience
J. Marvin¹, D. Malhotra², P. Jethwani², K. Belfield¹, E. Cohen¹
¹Yale New Haven Hospital, New Haven, CT, ²Section of Nephrology, Yale School of Medicine, New Haven, CT
*Purpose: Polyoma BK virus (BKV) is a ubiquitous DNA virus that is capable of reactivation and infection in kidney transplant recipients (KTR). Manifestations of the…
2022 American Transplant Congress
Single-Cell RNA Sequencing Identifies the Changes of Human Normal Kidney After Transplantation
G. Huang¹, H. Zhang¹, X. Chen¹, G. Zhao¹, J. Luo¹, S. Yang², J. Qiu¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, ²Department of Pathology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
*Purpose: We found that in all studies about kidney transplantation and single cell RNA sequencing (scRNA-seq), the native kidney rather than the transplanted kidney was…
2022 American Transplant Congress
Anti-CD80/86 Antibody (RM80/GL-1) Suppressed Murine Donor Specific Antibody Through Anergy CD4⁺T Cells
Y. Yamamoto¹, K. Uchida², K. Iguchi¹, M. Niimi³, M. Uchiyama¹
¹Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan, ²Juntendo University, Tokyo, Japan, ³Department of Surgery, Teikyo University, Tokyo, Japan
*Purpose: The interactions between CD80 and CD86 on antigen-presenting cells and CD28 on T cells may play an important role in alloimmune responses. We investigated…
2022 American Transplant Congress
Clinical Stratification of Pediatric Liver Transplant Recipients 4-5 Years Post-Transplant: 1^St Step Towards Personalized Management
W. Dixon¹, E. R. Perito¹, M. Tavakol¹, J. Bucuvalas², S. Feng¹
¹University of California, San Francisco, San Francisco, CA, ²Mount Sinai Kravis Children's Hospital and Recanati/Miller Transplantation Institute, Mount Sinai Health System, New York, NY
*Purpose: Recent surveillance biopsy studies strongly associate high normal ALT (>35U/L) with inflammatory histopathology and low normal ALT (15yrs (n=13; p=0.0006), chronic rejection (CR) diagnosis…
2022 American Transplant Congress
The Natural History of De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are key in the diagnosis of antibody-mediated rejection(ABMR) and are related to graft loss(GL). Luminex® provides semi-quantitative information with the…
2022 American Transplant Congress
Standard Induction with Basiliximab versus no Induction in Low Immunological Risk Kidney Transplant Recipients: Study Protocol for a Randomized Controlled Trial
A. Ajlan¹, H. Aleid¹, T. Ali¹, H. Joharji¹, Z. Alabdulkarim¹, T. Aburiash¹, K. Almeshari¹, A. Nazmi¹, Y. Shah¹, E. Devol¹, D. Alkortas¹, D. Broering¹, I. Alahmadi¹, A. Ullah¹, A. Alotaibi¹, A. Aljedai²
¹KFSHRC, RIYADH, Saudi Arabia, ²MOH, RIYADH, Saudi Arabia
*Purpose: To compare different induction therapeutic strategies with 2 doses of basiliximab vs. no induction in low immunologic risk kidney transplant recipients as per KFSHRC…
2022 American Transplant Congress
Leflunomide in Children with BK Polyomavirus Viremia After Kidney Transplant
J. Hewlett¹, K. Le Palma¹, L. Galea¹, J. Savant¹, S. Lopez¹, J. V. Rosano², A. Strong¹, B. Viteri¹, C. LaRosa¹, S. Amaral¹, B. Laskin¹
¹The Children's Hospital of Philadelphia, Philadelphia, PA, ²Yale New Haven Health, New Haven, CT
*Purpose: Studies examining the use of leflunomide in treating BK polyomavirus (BKPyV) viremia in children after kidney transplant are limited to case reports with small…
2022 American Transplant Congress
Baseline Predictors of Antimicrobial Utilization in Solid Organ Transplant Recipients
M. Govil¹, D. Xie¹, L. S. Hynan², S. L. Spitznogle¹, M. L. Monogue¹, J. Sanders¹, E. Bae¹, J. B. Cutrell¹, R. M. La Hoz¹
¹University of Texas Southwestern Medical Center, Dallas, TX, ²University of Texas at Southwestern, Dallas, TX
*Purpose: Antimicrobial use (AU) is a major driver of antimicrobial resistance but is understudied in solid organ transplant (SOT) recipients. Our study sought to quantify…
2022 American Transplant Congress
The Cost of Procuring Deceased Donor Livers: Evidence from OPO Cost Reports 2013-2018
J. Bragg-Gresham¹, T. Peters², F. McCormick³, J. Roberts⁴
¹University of Michigan, Ann Arbor, MI, ²University of Florida, Jacksonville, FL, ³Bank of America (Former), Walnut Creek, CA, ⁴University of California-San Francisco, San Francisco, CA
*Purpose: The cost of procuring deceased donor organ for transplantation include costs for the assessment of potential organ donors, maintenance of the donor while waiting…
2022 American Transplant Congress
Effectiveness of a Targeted Media Campaign on Engagement and Interest in Living Donation
L. A. Davis¹, A. Livingston², A. Waterman³
¹Houston Methodist Hospital, J.C. Walter Jr Transplant Center, Houston, TX, ²Multiview, Irving, TX, ³Transplant Research and Education Center, Houston, TX
*Purpose: Living donation rates have continued to decline. Research has suggested that disseminating living donation education and information more broadly to larger audiences outside of…