Am J Transplant, Volume 22, Suppl 3 Archives - Page 185 of 190 - ATC Abstracts

2022 American Transplant Congress
The Pre-Transplant Non-HLA Antibody Burden Predicts the Development of Histology of Antibody-Mediated Rejection After Kidney Transplantation
A. Senev¹, B. Ray², J. Hariharan², C. Heylen², M. Emonds¹, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Immucor Inc.,, Norcross, GA
*Purpose: Many kidney allografts fail due to the occurrence of antibody-mediated rejection (ABMR), related to donor-specific anti-HLA antibodies (HLA-DSA). However, the histology of ABMR can…
2022 American Transplant Congress
Single Port Robotic Kidney Transplantation: Comparison of Outcomes with Standard Open Kidney Transplantation
M. Eltemamy, A. Kaviani, Y. Lin, M. Abou Zeinab, V. Krishnamurthi, D. Goldfarb, J. Kaouk, A. Wee
Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH
*Purpose: To compare outcomes of the initial series of patients who underwent single port (SP) robotic kidney transplantation (KTP) with the standard open KTP.*Methods: Using…
2022 American Transplant Congress
Impact of Late and Recurrent Acute Graft Pyelonephritis on Long-Term Kidney Graft Outcomes
M. Pacaud¹, L. Colas¹, C. Kerleau², F. Le Borgne³, M. Giral², S. Brouard¹, J. Dantal²
¹CRT2I, Université de Nantes, Nantes, France, ²Service de Néphrologie et immunologie clinique, CHU de Nantes, Nantes, France, ³INSERM UMR 1246-SPHERE, Université de Nantes, Nantes, France
*Purpose: While Urinary tract infections are the most common infections in kidney transplant recipients, the impact of late acute graft pyelonephritis (AGPN) on graft outcomes…
2022 American Transplant Congress
Comparison of Outcomes in High Donation After Circulatory Death Liver Transplantation Usage Centers in the Acuity Circles Era
L. Chau¹, A. Mohamed², T. Kitajima¹, K. Collins³, M. Rizzari¹, A. Yoshida⁴, M. Abouljoud³, S. Nagai¹
¹Henry Ford Hospital, Detroit, MI, ²Department of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, ³Henry Ford Transplant Institute, Detroit, MI, ⁴Henry Ford Hospital, Grosse Pointe, MI
*Purpose: The recent acuity circles (AC) liver allocation policy has increased rates of donation after circulatory death (DCD) liver transplantation. We hypothesize transplant centers with…
2022 American Transplant Congress
Effect of Prophylactic Treatment of Osteoporosis on the Progression of Bone Mineral Density and Fractures in Lung Transplant Recipients – A Five-Year, Single-Center Experience
P. Singh¹, A. Ross², J. Mejia¹, T. E. Pesavento¹, S. Meng¹
¹Transplant nephrology, Ohio State University, Columbus, OH, ²Transplant nephrology, The Ohio State University, Columbus, OH
*Purpose: The incidence of osteoporotic fractures in lung transplant recipients (LTxR) is 35-50%. Due to this high incidence, we perform regular DEXA scans [pre-Tx, every…
2022 American Transplant Congress
Nocardia Infection and Associated Outcomes in Patients with Solid Organ Transplant
R. Munshi¹, J. Pellegrini Jr.¹, M. Lannom¹, N. Nehru², W. Olsthoorn², F. Anjum³
¹Internal Medicine, Nassau University Medical Center, West Hempstead, NY, ²American University of the Caribbean, Cupecoy, Saint Martin, ³Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA
*Purpose: Solid organ transplant (SOT) recipients face various challenges including increased risk of infections. Nocardia is a known pathogen for infecting immunosuppressed individuals, however, there…
2022 American Transplant Congress
Delivery of Plasmin During Machine Perfusion or Cold Storage Flush Improves Early Transplant Outcomes in aRat Dcd Liver Transplant Model
N. Abraham¹, M. Zhang¹, P. Cray², R. Neill¹, G. Cywinska¹, J. Migaly¹, R. Kahan¹, A. Pontula¹, J. Penaflor¹, Q. Gao¹, K. P. Samy¹, J. J. Pollara², V. Novokhatny³, M. G. Hartwig¹, A. S. Barbas¹
¹Duke Division of Abdominal Transplant Surgery, Duke Ex-Vivo Organ Lab (DEVOL), Durham, NC, ²Duke Division of Surgical Sciences, Pollara lab, Durham, NC, ³Bioscience Industrial Group, Grifols R&D, Durham, NC
*Purpose: Ischemic injury of the peribiliary glands and vascular plexus has been described in DCD livers and correlates with the development of cholangiopathy. Investigators have…
2022 American Transplant Congress
Delivery of Extracellular Matrix Targeted Regulatory T Cells by Novel Nanofiber Coatings for Transplantation Therapies
L. Gallon¹, J. K. Carrow², J. He¹, Y. Sambandam¹, X. Lai¹, J. Mathew¹, L. C. Palmer², J. R. Leventhal¹, Z. Zhang¹, S. I. Stupp²
¹Surgery - Transplant, Northwestern University, Chicago, IL, ²Simpson Querrey Institute, Northwestern University, Chicago, IL
*Purpose: Regulatory CD4+CD25+FOXP3+ T cells (Tregs) have been shown to induce tolerance in transplantation models and can mitigate transplant rejection or injury following ischemic reperfusion…
2022 American Transplant Congress
Longitudinal Analysis of the Gut Microbiota Structure and Function After Renal Transplantation
A. Vaitkute¹, F. Yuen Chang¹, A. Greco², S. Chong¹, H. Mahdi³, M. Bajaj-Elliott², A. Pesenacker¹, R. Motallebzadeh¹
¹Institute of Immunity and Transplantation, UCL, London, United Kingdom, ²Institute of Child Health, UCL, London, United Kingdom, ³Department of Renal Medicine, UCL, London, United Kingdom
*Purpose: Despite marked improvements in outcomes after renal transplantation, graft loss from alloimmune pathology and adverse side effects including urinary tract infections and diarrhoea remain…
2022 American Transplant Congress
Specificity and Avidity of Donor MHC-Specific B Cells in Naive, Rejecting and Tolerant Mice
I. Sayin¹, S. Khiew², D. Yin¹, P. Sage³, C. B. Cavazzoni³, R. King⁴, A. Chong¹
¹Department of Surgery, University of Chicago, Chicago, IL, ²Merck, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Department of Microbiology, University of Alabama, Birmingham, AL
*Purpose: Antibody-mediated rejection is recognized as an important mediator of graft loss in the clinic, and the induction of donor-specific B cell tolerance may contribute…