Am J Transplant, Volume 22, Suppl 3 Archives - Page 183 of 190 - ATC Abstracts

2022 American Transplant Congress
Defining New Arterial and Arteriolar Lesions Accompanying Transplant Glomerulopathy: Potential Additions to the Histologic Assessment of ABMR
A. Perkowska-Ptasinska¹, D. Deborska-Materkowska², M. Ciszek³, M. Myslak⁴, J. Chang⁵, J. Reeve⁶, P. Halloran⁷
¹Pathology, Medical University of Warsaw, Warsaw, Poland, ²Transplantation Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland, ³Immunology, Transplantation Medicine and Internal Diseases, Medical University of Warsaw, Warsaw, Poland, ⁴Infectious Diseases, Hepatology and Liver Transplantation, Pomeranian Medical University, Szczecin, Poland, ⁵Alberta Transplant Applied Genomics Center, Edmonton, AB, Canada, ⁶Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ⁷Pathology, Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada
*Purpose: Transplant glomerulopathy (TG) results from chronic endothelial injury most commonly related to ABMR. Surprisingly, except for PTC, the relation between TG and other vascular…
2022 American Transplant Congress
Performance of Donor Derived Cell Free DNA (dd-cfDNA) in Diagnosing Subclinical and Clinical Acute Rejection in Kidney Transplant Recipients
T. Cober, P. West-Thielke, C. Miller, N. Grund, M. Altrich, A. Sutton, R. Sinha, M. Miller, S. Kleiboeker, J. Weems
Eurofins, Framingham, MA
*Purpose: The aim of this study was to examine the performance of Viracor TRAC donor derived cell free DNA (dd-cfDNA) in for-cause biopsies as well…
2022 American Transplant Congress
Evaluation of Technical Bladder Complications in Kidney Transplantation Recipients with a Prolonged Dialysis History
S. M. Zielsdorf, K. Kushwaha, C. Goldbeck, S. Martin, Y. Kwon, K. Etesami, J. Kim, J. Emamaullee, S. Zielsdorf
University of Southern California, Los Angeles, CA
*Purpose: The kidney transplant (KT) waiting list continues to expand, resulting in prolonged dialysis times of >8 years prior to transplantation in some regions. The…
2022 American Transplant Congress
De Novo Anti-Brush Border Antibody Disease in a Kidney Transplant Recipient
P. Yenebere, D. Ibrahim, T. Nadasdy, R. Daloul
Ohio State University, Columbus, OH
*Purpose: Anti-brush border antibody (ABBA) disease is very rare, characterized by tubulointerstitial damage caused by autoantibodies against LDL receptor-related protein 2 (LRP2) in the proximal…
2022 American Transplant Congress
Characterization Of Local Antibody Responses In Human Cardiac Allograft Vasculopathy
S. B. See¹, L. J. Stanton¹, P. Roy¹, S. Mashiko¹, E. R. Vasilescu², C. C. Marboe², M. Szabolcs², M. V. Habal³, M. Farr³, S. Restaino³, Y. Naka⁴, D. M. Mancini⁵, J. C. Madsen⁶, R. G. King⁷, E. P. Kransdorf⁸, E. Zorn¹
¹CCTI, Columbia University Irving Medical Center, New York, NY, ²Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, ³Medicine, Columbia University Irving Medical Center, New York, NY, ⁴Surgery, Columbia University Irving Medical Center, New York, NY, ⁵Cardiology, Icahn School of Medicine, New York, NY, ⁶CTS, Massachusetts General Hospital, Boston, MA, ⁷Microbiology, University of Alabama, Birmingham, AL, ⁸Cedars-Sinai Heart Institute, Los Angeles, CA
*Purpose: Cardiac allograft vasculopathy (CAV) is the leading cause of heart graft recipient mortality after five years post-transplant. A major hurdle to improving outcomes is…
2022 American Transplant Congress
Immunotherapy Before Solid Organ Transplantation: An International Transplant Community-Focused Survey
T. Ivanics¹, M. P. Claasen¹, D. Al-Adra², G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada
*Purpose: The use of immunotherapy for cancer has increased and is expected to continue to grow. The outcomes after solid organ transplantation (SOT) in patients…
2022 American Transplant Congress
Donor Macrophage Depletion Improves Kidney Graft Function Despite Long Cold Ischemia
C. Jordan¹, A. Dangi², X. Luo¹
¹Duke University School of Medicine, Durham, NC, ²Medicine, Duke University, Durham, NC
*Purpose: Prolonged cold ischemia is a known risk factor for delayed graft function and poorer outcomes after kidney transplantation. Overcoming this obstacle is key to…
2022 American Transplant Congress
Influence of Regulatory B Cells on B Cells
Q. Fu¹, K. M. Lee², K. Deng², D. Agarwal¹, R. Matheson³, T. Press¹, J. Lei⁴, H. Yang⁵, C. LeGuern², S. Deng⁵, J. F. Markmann²
¹Center for Transplant Science, MGH, Boston, MA, ²Massachusetts General Hospital, Boston, MA, ³Transplantation Surgery Research, Massachusetts General Hospital, Boston, MA, ⁴Surgery, Mass General, Boston, MA, ⁵Sichuan Provincial People's Hospital, University of Electronic Sciences and Technology of China, Chengdu, China
*Purpose: Our previous study showed that Bregs-TLR, one type of previously studied Breg expanded in vitro, are capable of suppressing naïve B cell proliferation in…
2022 American Transplant Congress
NecroX-7 Ameliorate FK506-Induced Nephrotoxicity in LLC-PK1 Cells (Pig Kidney Epithelial Cells)
H. J. Jang
Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea, Republic of
*Purpose: Tacrolimus (FK506) is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and…
2022 American Transplant Congress
Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study
K. E. Karakasi¹, G. Katsanos², I. Karolos³, V. Tsioukas³, G. Tsoulfas⁴
¹University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, ²Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, ³School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, ⁴University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece
*Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…