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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Rejection After Liver Transplantation: What Can We Learn from Transcriptomic Analysis?

    H. J. Braun1, D. Amara2, A. Zarinsefat1, G. Szabo1, Z. Laszik1, P. Stock1, N. Ascher1

    1University of California, San Francisco, San Francisco, CA, 2UCLA, Los Angeles, CA

    *Purpose: Acute cellular rejection (ACR) can occur at any time following liver transplantation (LT); initial ACR within 6 months is most common and occurs in…
  • 2022 American Transplant Congress

    Status 7: Parking Lot or Loading Zone?

    E. Wells, M. Robinson, S. Blais, A. Chacon, S. Greve, R. Villicana, C. Bratton, K. Talavera, M. de Vera, S. Regmi, T. Hoang, J. Woloszyn, R. Rattanavich

    Transplant Institute, Loma Linda University Health, Loma Linda, CA

    *Purpose: Kidney waitlist management continues to be a challenge for many transplant centers for a variety of reasons. Over the years, the number of Status…
  • 2022 American Transplant Congress

    A Pilot Study Using Registry-Based External Controls for the Cyclosporine Arm of the BENEFIT Study

    A. Klein1, D. Stewart2, A. Toll2, W. E. Fitzsimmons1

    1Transplant Therapeutics Consortium, Critical Path Institute, Tucson, AZ, 2UNOS, Richmond, VA

    *Purpose: The Transplant Therapeutics Consortium established a real-world evidence workgroup evaluating the potential of supplementing internal control arms with external controls to understand the impact…
  • 2022 American Transplant Congress

    Use of Dd-cfdna to Guide Tapering of Immunosuppression Therapy in Kidney Transplant Recipients

    G. Osuchukwu1, A. Trevino1, L. Beretich2, S. McCormick2, N. Kaur2, R. White2, P. Gauthier2

    1Victoria Kidney and Dialysis Associates, Victoria, TX, 2Natera, Inc., Austin, TX

    *Purpose: Continuous administration of immunosuppressive therapy (IST) is required to avoid allograft rejection in transplant recipients. However, these therapeutic interventions can lead to significant side…
  • 2022 American Transplant Congress

    Evaluating the Risk and Benefit of Once Daily Delayed Release Mycophenolate in Pediatric Kidney Transplant Recipients

    L. Maestretti1, A. McGrath1, A. Fong1, A. Brubaker2, A. Gallo3, P. Grimm3, A. Chaudhuri3

    1Pediatric Kidney Transplant, Stanford Children's Health, Palo Alto, CA, 2Transplant Surgery, Stanford University, Palo Alto, CA, 3Stanford University, Palo Alto, CA

    *Purpose: Medication non-adherence continues to particularly affect adolescent kidney transplant recipients. Standard immunosuppressive regimen at our center includes tacrolimus, and mycophenolate with or without steroids.…
  • 2022 American Transplant Congress

    Impact of Donor-Recipient Age Discrepancy in Living Donor Kidney Transplantation – The Need for Better Matching

    N. K. Prabhu1, V. Villani1, K. P. Samy1, D. Sudan1, K. Ravindra1, W. Irish2

    1Surgery, Duke University Medical Center, Durham, NC, 2Surgery, East Carolina University, Greenville, NC

    *Purpose: The Kidney Allocation System (KAS) was implemented in 2014 to address donor-recipient matching in deceased donor kidney transplantation, with the goal of maximizing life-years…
  • 2022 American Transplant Congress

    The Performance of the Kidney Donor Profile Index in Predicting Outcomes for Kidney Transplant Recipients of Standard Criteria Donors: Results from a Brazilian Single-Center Cohort Study

    A. Morais, R. D. Foresto, J. Medina-Pestana, H. Tedesco-Silva, L. R. Requião-Moura

    Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil

    *Purpose: To evaluate the performance of the Kidney Donor Profile Index (KDPI) in predicting outcomes for kidney transplant recipients (KTR) of standard criteria donors (SCD)…
  • 2022 American Transplant Congress

    Experience with the First Two Living Donor Robotic Left Lobe Hepatectomies in the USA

    M. E. Tobon Lascano, M. Akoad, C. Simon, J. Kim, Y. Cheah

    Transplant, Lahey Clinic, Burlington, MA

    *Purpose: Robotic living donor has been performed in a few centers with good outcomes; the first report of a robotic right lobe donor hepatectomy was…
  • 2022 American Transplant Congress

    Deep Learning Identifies Arterial Intimal Fibrosis in Kidney Transplant Biopsies

    K. Liu1, Z. Yi2, S. Ward3, F. Salem3, W. Zhang2

    1Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, 2Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 3Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: Arterial intimal fibrosis (AIF) is the excessive fibrotic tissue formation in the intima of arteries indicative of poor graft function after kidney transplant. Visual…
  • 2022 American Transplant Congress

    Differential Impact of Subclinical Kidney Transplant Rejection in Young Adults

    S. Raza1, G. Agarwal1, H. Fatima1, R. Gaston1, V. Hauptfeld-Dolesjek1, B. Julian1, C. Kew1, V. Kumar1, S. Mehta1, S. Ong1, F. Rosenblum1, G. Towns1, R. Mannon2, M. Seifert1

    1School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 2College of Medicine, University of Nebraska, Omaha, NE

    *Purpose: Serum creatinine, while an insensitive biomarker of allograft injury, is the current standard for assessing the stability of allograft function and guiding kidney transplant…
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