Am J Transplant, Volume 22, Suppl 3 Archives - Page 175 of 190 - ATC Abstracts

2022 American Transplant Congress
Designing Continuous Distribution for Liver Allocation
M. Mankowski¹, N. Wood², D. Segev³, S. Gentry²
¹Erasmus University, Rotterdam, Netherlands, ²US Naval Academy, Annapolis, MD, ³Johns Hopkins University, Baltimore, MD
*Purpose: The continuous distribution framework is required for all future organ allocation policies. Continuous distribution changes the allocation paradigm, prioritizing candidates according to a composite…
2022 American Transplant Congress
Meld/Peld Exception Policy and Outcomes in Children with Hepatopulmonary Syndrome Requiring Liver Transplantation in the United States
M. H. Raza¹, P. Kobierski¹, A. Misra², A. Lim³, C. Goldbeck², K. Etesami², R. Kohli⁴, J. Emamaullee²
¹Keck School of Medicine of USC, Los Angeles, CA, ²Surgery, University of Southern California, Los Angeles, CA, ³University of Southern California, Los Angeles, CA, ⁴Liver Transplant Program, Children's Hospital-Los Angeles, Los Angeles, CA
*Purpose: Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplant (LT) candidates. Children with HPS are currently granted MELD/PELD exception for LT…
2022 American Transplant Congress
Outcomes in Pediatric Intestinal Retransplantation
E. J. Lee¹, G. Mazariegos¹, K. Soltys¹, G. Bond¹, A. Ganoza¹, J. Rudolph², S. Horslen², R. Sindhi¹, A. Khanna¹
¹Transplant Surgery, UPMC, Pittsburgh, PA, ²Division of Gastroenterology, Hepatology and Nutrition,, UPMC, Pittsburgh, PA
*Purpose: Historically, intestinal retransplantation (Re-ITx) has been associated with high morbidity and mortality.*Methods: Retrospective chart review of patients who underwent Re-ITx at our institution between…
2022 American Transplant Congress
Enhanced Delivery of Nanomedicine to Human Kidney During Ex Vivo Perfusion
C. Albert¹, L. Bracaglia¹, A. Koide², J. R. DiRito¹, T. Lysyy¹, E. Christopher¹, J. Grundler¹, J. T. Langford¹, D. Haakinson¹, J. S. Pober¹, W. M. Saltzman¹, S. Koide², G. Tietjen¹
¹Yale University, new haven, CT, ²Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY
*Purpose: An efficient delivery of therapeutic agents to graft endothelial cells (ECs) prior to transplantation could render organs more resistant to injury, improving clinical outcomes…
2022 American Transplant Congress
Chimeric Antigen Receptor Regulatory T Cells (CAR-Tregs) Provide Significantly Greater Modulation of Alloimmune Responses Than Alternative Alloantigen-Specific Treg Strategies
A. S. Kurt¹, P. Ruiz¹, E. Kodela¹, G. Lombardi¹, M. Martinez-Llordella², A. Sanchez-Fueyo¹
¹King's College London, London, United Kingdom, ²Quell Therapeutics, London, United Kingdom
*Purpose: Conferring alloantigen-specificity to ex vivo expanded CD4+CD25+Foxp3+ Tregs increases their capacity to counteract effector alloimmune responses following adoptive transfer into transplant recipients. This has…
2022 American Transplant Congress
Sarcopenia and Testosterone Deficiency with Chronic Liver Disease; Post-Liver Transplant Utility of Short Term Testosterone Replacement Therapy
A. Jain¹, D. Haussner²
¹Penn State Health Milton S. Hershey Medical Center, Hershey, PA, ²Presbyterian, New York, NY
*Purpose: Chronic liver disease is often associated with testosterone deficiency. However, testosterone therapy does not improve survival. So far, after a successful liver transplant (LTx),…
2022 American Transplant Congress
Development Process of Minimally Invasive Living Donor Liver Transplantation (from Pure Laparoscopic Explant Hepatectomy to Robotic Graft Implantation)
K. Suh, S. Hong, S. Lee, S. Suh, S. Hong, E. Han, Y. Choi, N. Yi, K. Lee
Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: With the accumulation of experience in pure laparoscopic hepatectomy, including donor hepatectomy, our center initiated a minimally invasive living donor liver transplantation (LDLT) program…
2022 American Transplant Congress
Use of Three-Dimensional (3D) Modeling Software for Preoperative Anatomical Assessment in Living Donor Nephrectomy
M. McCabe¹, K. Dokus², A. Nair², K. Pineda-Solis², E. Venniro¹, J. Taylor¹, M. Orloff², R. Hernandez¹, R. Kashyap²
¹University of Rochester School of Medicine and Dentistry, Rochester, NY, ²University of Rochester Medical Center, Rochester, NY
*Purpose: Successful and safe completion of living donor nephrectomy depends on donor anatomy. Preoperative imaging is imperative to determine operative feasibility and to avoid unexpected…
2022 American Transplant Congress
Use of Monoclonal Antibodies for Treatment of Solid Organ Transplant Recipients with COVID-19: A Single Center Experience
S. Anjan¹, C. Vu², A. Vega², M. Maxam², J. Bini Viotti³, Y. Natori¹, J. Simkins¹, A. Khatri³, A. Mattiazzi¹, R. Vianna¹, J. Cienki², L. Lee², G. Guerra¹, L. Abbo²
¹Miami Transplant Institute, Miami, FL, ²Jackson Health System, Miami, FL, ³University of Miami Miller School of Medicine, Miami, FL
*Purpose: The risk of severe COVID-19 requiring hospitalization and death is higher in solid organ transplant recipients (SOTr). There remains limited data on the use…
2022 American Transplant Congress
The Intracellular Tacrolimus Concentration in CD3⁺ T Lymphocytes and CD14⁺ Monocytes and Its Association with Kidney Transplant Rejection
S. Udomkarnjananun, C. Baan, B. de Winter, D. Hesselink
Erasmus MC, Rotterdam, Netherlands
*Purpose: The intracellular tacrolimus concentration in peripheral blood mononuclear cells (PBMCs) (TAC[PBMC]) was proposed to better represent active concentration than pre-dose whole blood concentration (C0).…