Am J Transplant, Volume 22, Suppl 3 Archives - Page 173 of 190 - ATC Abstracts

2022 American Transplant Congress
Clinical Relevance of Absolute BK Polyoma Viral Load Kinetics in Patients with Biopsy Proven BK Polyomavirus Associated Nephropathy
H. Omic¹, J. P. Kläger¹, H. Herkner¹, S. W. Aberle¹, H. Regele¹, L. Weseslindtner¹, T. A. Schrag¹, G. Bond¹, K. Hohenstein¹, B. Watschinger¹, J. Werzowa², R. Strassl¹, M. Eder¹, Z. Kikic¹
¹Medical University of Vienna, Vienna, Austria, ²Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 1st Medical Department, Hanusch Hospital, Vienna, Austria
*Purpose: The absolute BK viral load is an important diagnostic surrogate for BK polyomavirus associated nephropathy (PyVAN) after renal transplant (KTX) and serial assessment of…
2022 American Transplant Congress
Evolution of Donor-Derived Cell-Free DNA During the First Week After Surgery Predicts Renal Function Recovery After Kidney Transplantation
D. Cucchiari¹, E. Cuadrado¹, E. Gonzalez¹, J. Puig¹, M. Ramirez-Bajo¹, P. Ventura-Aguiar¹, I. Revuelta², B. Bayès¹, F. Diekmann¹
¹Hospital Clínic de Barcelona, Barcelona, Spain, ²Hospital Clinic de Barcelona, Barcelona, Spain
*Purpose: Donor-derived cell-free DNA (ddcfDNA) is usually employed starting from the second week after kidney transplantation (KT), as its earlier increase can be due to…
2022 American Transplant Congress
Association Between Maintenance Immunosuppressive Regimens And Covid-19 Mortality In Kidney Transplant Recipients
A. O. Gérard¹, S. Barbosa², D. Anglicheau³, L. Couzi⁴, M. Hazzan⁵, O. Thaunat⁶, G. Blancho⁷, S. Caillard⁸, A. Sicard¹
¹Nephrology, Nice University Hospital, Nice, France, ²Institute of Molecular and Cellular Pharmacology, CNRS, Valbonne, France, ³Nephrology, Necker University Hospital, APHP, Paris, France, ⁴Nephrology, Bordeaux Pellegrin University Hospital, Bordeaux, France, ⁵Nephrology, Lille University Hospital, Lille, France, ⁶Nephrology, Edouard Herriot Hospital, Hospices civils de Lyon, Lyon, France, ⁷Nephrology, Nantes University Hospital, Nantes, France, ⁸Nephrology, Strasbourg University Hospital, Strasbourg, France
*Purpose: Kidney transplant recipients (KTR) are at increased risk of mortality from COVID-19. We conducted a cohort study among KTR from the French Solid Organ…
2022 American Transplant Congress
Antibody Response to Sars-CoV-2 Vaccine Among Kidney Transplant Recipients: A Retrospective Cohort Study
H. Ishida¹, K. Unagami², K. Ishii³, T. Kanzawa², T. Yagisawa⁴, K. Tanabe², M. Furusawa²
¹Tokyo Women's, Tokyo, Japan, ²Tokyo Women's Medical University, Tokyo, Japan, ³Tokyo Wimen's Medical University, Tokyo, Japan, ⁴Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: We examined a positivity of corona virus antibody in kidney transplant recipients who received two-doses BNT162B2 (mRNA) vaccination during the beginning 6 months in…
2022 American Transplant Congress
Designing Continuous Distribution for Liver Allocation
M. Mankowski¹, N. Wood², D. Segev³, S. Gentry²
¹Erasmus University, Rotterdam, Netherlands, ²US Naval Academy, Annapolis, MD, ³Johns Hopkins University, Baltimore, MD
*Purpose: The continuous distribution framework is required for all future organ allocation policies. Continuous distribution changes the allocation paradigm, prioritizing candidates according to a composite…
2022 American Transplant Congress
Meld/Peld Exception Policy and Outcomes in Children with Hepatopulmonary Syndrome Requiring Liver Transplantation in the United States
M. H. Raza¹, P. Kobierski¹, A. Misra², A. Lim³, C. Goldbeck², K. Etesami², R. Kohli⁴, J. Emamaullee²
¹Keck School of Medicine of USC, Los Angeles, CA, ²Surgery, University of Southern California, Los Angeles, CA, ³University of Southern California, Los Angeles, CA, ⁴Liver Transplant Program, Children's Hospital-Los Angeles, Los Angeles, CA
*Purpose: Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplant (LT) candidates. Children with HPS are currently granted MELD/PELD exception for LT…
2022 American Transplant Congress
Outcomes in Pediatric Intestinal Retransplantation
E. J. Lee¹, G. Mazariegos¹, K. Soltys¹, G. Bond¹, A. Ganoza¹, J. Rudolph², S. Horslen², R. Sindhi¹, A. Khanna¹
¹Transplant Surgery, UPMC, Pittsburgh, PA, ²Division of Gastroenterology, Hepatology and Nutrition,, UPMC, Pittsburgh, PA
*Purpose: Historically, intestinal retransplantation (Re-ITx) has been associated with high morbidity and mortality.*Methods: Retrospective chart review of patients who underwent Re-ITx at our institution between…
2022 American Transplant Congress
Enhanced Delivery of Nanomedicine to Human Kidney During Ex Vivo Perfusion
C. Albert¹, L. Bracaglia¹, A. Koide², J. R. DiRito¹, T. Lysyy¹, E. Christopher¹, J. Grundler¹, J. T. Langford¹, D. Haakinson¹, J. S. Pober¹, W. M. Saltzman¹, S. Koide², G. Tietjen¹
¹Yale University, new haven, CT, ²Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY
*Purpose: An efficient delivery of therapeutic agents to graft endothelial cells (ECs) prior to transplantation could render organs more resistant to injury, improving clinical outcomes…
2022 American Transplant Congress
Chimeric Antigen Receptor Regulatory T Cells (CAR-Tregs) Provide Significantly Greater Modulation of Alloimmune Responses Than Alternative Alloantigen-Specific Treg Strategies
A. S. Kurt¹, P. Ruiz¹, E. Kodela¹, G. Lombardi¹, M. Martinez-Llordella², A. Sanchez-Fueyo¹
¹King's College London, London, United Kingdom, ²Quell Therapeutics, London, United Kingdom
*Purpose: Conferring alloantigen-specificity to ex vivo expanded CD4+CD25+Foxp3+ Tregs increases their capacity to counteract effector alloimmune responses following adoptive transfer into transplant recipients. This has…
2022 American Transplant Congress
Sarcopenia and Testosterone Deficiency with Chronic Liver Disease; Post-Liver Transplant Utility of Short Term Testosterone Replacement Therapy
A. Jain¹, D. Haussner²
¹Penn State Health Milton S. Hershey Medical Center, Hershey, PA, ²Presbyterian, New York, NY
*Purpose: Chronic liver disease is often associated with testosterone deficiency. However, testosterone therapy does not improve survival. So far, after a successful liver transplant (LTx),…