2022 American Transplant Congress
Simultaneous Liver/ Kidney Transplant Reduces Both Donor Specific and Non-Donor Specific HLA Antibodies
Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Kidney allografts can be transplanted across strong donor specific antibody (DSA) barriers in simultaneous liver/kidney transplant (SLK) recipients. It is suggested that preformed DSAs…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…2022 American Transplant Congress
Improving Access and Equity for Transplant: A Single-Center Experience
*Purpose: Many Hispanic Americans have misconceptions about transplantation due to language and cultural differences, which can make them less likely to undergo liver transplant (LT)…2022 American Transplant Congress
Ventricular Modeling Following Bariatric Surgery Decreases Need for Heart Transplantation
*Purpose: For obese patients with congestive heart failure (CHF), aggressive weight loss has been associated with ventricular remodeling. Many have suggested offering bariatric surgery for…2022 American Transplant Congress
Failure to Account for Social Determinants of Health in Non-HCC MELD Exceptions Exacerbates Geographic Disparities in Access to Liver Transplantation
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Non-HCC MELD exceptions have been previously shown to give excess priority for transplant in certain UNOS Regions, but this phenomenon has not been examined…2022 American Transplant Congress
Liver Transplantation for Patients with Fibrolamellar Hepatocellular Carcinoma: A Comprehensive Multicenter Analysis to Support Future Decision Making
*Purpose: Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare tumour accounting for ~1% of all primary liver cancers. Due to its rarity, there is a shortage…2022 American Transplant Congress
Metabolic Outcomes After Pancreas Transplant Alone from Donation After Circulatory Death Donor – The UK Registry Analysis
*Purpose: Extrapolating data from early DCD (donation after circulatory death) kidney transplantation, pancreas transplants from DCD grafts were feared to have worse metabolic outcomes. Hence,…2022 American Transplant Congress
Ultrasound Targeted Microbubble Cavitation During Ex Vivo Normothermic Machine Perfusion Reduces Peribiliary Vascular Plexus Thrombi and Graft Injury in a DCD Liver Transplant Model
*Purpose: Thrombus formation in the peribiliary vascular plexus (PBP) is a proposed mechanism for ischemic cholangiopathy (IC) after liver transplantation from donors after circulatory death…2022 American Transplant Congress
Outcomes of Sensitized Simultaneous Liver-Kidney Transplant
David Geffen School of Medicine, Los Angeles, CA
*Purpose: Pre-formed donor-specific HLA antibodies (DSAs) in simultaneous liver-kidney transplants (SLKTs) have been associated with increased risk of antibody mediated rejection (AMR) and negative transplant…2022 American Transplant Congress
Clinical Significances Of Anti-collagen Type I And Type Iii Antibodies In Antibody-mediated Rejection
*Purpose: It is important to determine the clinical significance of non-human leukocyte antigen (HLA) antibodies and their association with antibody-mediated rejection (ABMR) of kidney allografts.*Methods:…
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