ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Evolving Trends In The Management And Outcome Of Duodenal Complications After Pancreas Transplantation: A 20-year Single Institution Experience

    S. Ray1, C. Parmentier1, G. Sapisochin1, A. Yousuf1, I. McGilvray1, A. Norgate1, M. Cattral1, M. Selzner2, T. Reichman3

    1Multiorgan transplantation, Toronto general hospital, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3University of Toronto/The University Health Network, Toronto, ON, Canada

    *Purpose: Duodenal leaks have been a sinister complication in any major gastro-intestinal operation. With an incidence ranging from 4-10%, these have been one of the…
  • 2022 American Transplant Congress

    Transitional-1 B Cell IL-10/TNFα Ratio Risk-Stratifies Renal Transplant Patients with Early Borderline Change

    A. Cherukuri, P. Randhawa, S. Hariharan, D. Rothstein

    Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA

    *Purpose: Recent studies have shown that Banff borderline change (BLC) on allograft biopsies (Bx) is associated with decreased graft survival. However, many patients with BLC…
  • 2022 American Transplant Congress

    Outcome Predictors with Perioperative Kidney Transplant Midodrine Usage

    R. Watson1, S. Mullins2, S. Williams3, F. Fakhre4, K. Robichaux4, S. Mohammed4, M. Gosselin3, A. Kumar5, J. Buggs1, V. Bowers1

    1Transplant Surgery, Tampa General Hospital, Tampa, FL, 2Florida A &M University, Tallahassee, FL, 3University of Tampa, Tampa, FL, 4University of South Florida, Tampa, FL, 5Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Midodrine is an alpha-1 agonist drug commonly used to aid hypotension in kidney transplant patients. Little is described regarding outcomes with midodrine in kidney…
  • 2022 American Transplant Congress

    Evaluation of Post-Transplant Angiotensin II Type 1 Receptor Antibodies, Donor-Derived Cell-Free DNA, and Rejection in Heart Transplant Recipients

    B. Agegnehu1, S. Sterling1, R. Winstead1, I. Tchoukina2

    1Pharmacy, VCU Health System, Richmond, VA, 2Advanced Heart Failure and Transplant Cardiology, VCU Health System, Richmond, VA

    *Purpose: There is limited evidence evaluating the relationship between angiotensin II type 1 receptor antibodies (AT1R-Abs), donor-derived cell-free DNA (dd-cfDNA), and rejection in heart transplant…
  • 2022 American Transplant Congress

    The Impact of Neutralizing Antibodies on Polyomavirus Infections in Mice

    D. R. Butcher, B. D. Thompson, H. K. Singh, V. Nickeleit

    Pathology and Laboratory Medicine, UNC Chapel Hill School of Medicine, Chapel Hill, NC

    *Purpose: Definitive polyomavirus nephropathy (PyVN) affects kidney transplants and impacts allograft function and survival. Data suggest that neutralizing PyV strain specific antibodies can attenuate and…
  • 2022 American Transplant Congress

    CEACAM1 Splice Isoforms Are Regulated by Hypoxia Inducible Factors 1 alpha (HIF-1a) to Protect Against Ischemic Injury in Mouse and Human Liver Transplantation

    K. J. Dery1, H. Kojima1, K. Kadono2, H. Hirao1, J. Kupiec-Weglinski3

    1UCLA, Los Angeles, CA, 2Liver Transplant Surgery, UCLA, Los Angeles, CA, 3UCLA Medical Center, Los Angeles, CA

    *Purpose: CEACAM1 (CC1) is a transmembrane glycoprotein that undergoes extensive alternative splicing (AS) to generate CC1-S and CC1-L. It is currently unclear which of these…
  • 2022 American Transplant Congress

    Multiomic Analyses Of Two Pig Kidney To Human Xenotransplants

    B. Keating1, B. Piening2, M. Mangiola3, J. Stern4, W. Zhang5, A. Griesemer6, B. Lonze7, M. Snyder8, J. Boeke5, R. Montgomery7

    1University of Pennsylvania, Philadelphia, PA, 2Providence Cancer Center, Portland, OR, 3New York University Langone Medical Center, New York, NY, 4Department of Surgery, NYU Langone, New York, NY, 5Institute of Systems Genetics, NYU Langone, New York, NY, 6Surgery, NYU Langone, New York, NY, 7NYU Langone Transplant Institute, New York, NY, 8Genetics, Stanford, Palo Alto, CA

    *Purpose: Organ shortage remains a major limitation within transplantation, with waiting lists greatly outpacing the number of donors available. Pig organs offer significant advantages for…
  • 2022 American Transplant Congress

    Impact of Recipient Warm Ischemic Time on Outcomes Associated with High KDPI and DCD Donor Kidneys: Cold Ischemic Time Remains Paramount

    M. L. Jacobs, R. Stratta, M. Garner, B. Sharda, A. Farney, G. Orlando, A. Reeves-Daniel, C. Jay

    Department of Surgery, Atrium Health Wake Forest Baptist, Winston Salem, NC

    *Purpose: Previously we demonstrated that cold ischemic time (CIT) beyond 24 hours was an important risk predictor of early graft loss (EGL) and primary non-function…
  • 2022 American Transplant Congress

    Use of New 2021 CKD-EPI as an Endpoint in Transplant Trials May Significantly Influence Observations

    E. Yanqui1, H. Hames1, T. Shi2, A. R. Shields1, E. S. Woodle1, R. R. Alloway1

    1University of Cincinnati, Cincinnati, OH, 2CCHMC, Cincinnati, OH

    *Purpose: GFR equations have recently been modified primarily to avoid disadvantaging black populations. The purpose of this study was to evaluate renal function and the…
  • 2022 American Transplant Congress

    Identifying Predictors of Pediatric Heart Only versus Combined Heart-Liver Transplantation

    K. Zhang, S. Chen, A. Syed, A. Gallo, C. Esquivel, C. Bonham, S. Hollander, M. Ma, J. Han, N. Ebel

    Stanford University, Stanford, CA

    *Purpose: A standardized protocol to identify which patients with Fontan failure require combined heart liver transplant (cHLT) versus isolated heart transplant (HT) has not yet…
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