ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Prevalence and Clinical Significance of Pancreatic Cystic Lesions in Immunosuppressed Patients with Solid Organ Transplantation

    Y. Yu, H. Jo, Y. Choi, J. Lee, D. Kim

    HBP surgery and liver transplantation, Korea University College of Medicine and School of Medicine, Seoul, Korea, Republic of

    *Purpose: Solid organ transplant recipients have an increased risk of cancer due to immunosuppressive therapy. Pancreatic cystic lesions (PCLs) are increasingly being detected, some with…
  • 2022 American Transplant Congress

    First-in-Human Clinical-Grade Porcine Kidney Xenotransplant

    J. E. Locke1, B. Orandi1, V. Kumar1, J. Houp1, D. Anderson1, V. Hauptfeld1, D. Martin2, C. Killian1, S. Macedon1, N. Budd1, K. Stegner1, A. Dandro3, M. Kokkinaki3, K. Kuravi3, R. Reed4, H. Fatima1, G. Baker1, J. Perry1, E. Bryant1, M. Cheung1, E. Erman1, K. Kraebber1, T. Gamblin1, L. Guy1, D. Ayares3, P. Porrett1

    1University of Alabama at Birmingham, Birmingham, AL, 2Deakin University, Geelong, Australia, 3Revivicor, Incorporated, Blacksburg, VA, 4University of Alabama at Birmingham, Irondale, AL

    *Purpose: Proof-of-concept xenotransplant work has been performed in pig to non-human primates (NHP), but it is unclear if outcomes can be recapitulated in humans. While…
  • 2022 American Transplant Congress

    The Post-operative Clinical Outcomes Of 59 Tanrp Cases In An International Cohort

    J. Louca1, N. Patel1, S. Messer2, J. Chindu2, S. Large2

    1Cambridge University, Cambridge, United Kingdom, 2Royal Papworth Hospital, Cambridge, United Kingdom

    *Purpose: Heart transplantation is an immensely effective service and is currently the only definitive treatment for heart failure. However, transplantation is limited by donor availability.…
  • 2022 American Transplant Congress

    Comparing Long-Term Outcomes of Steroid-Based versus Steroid-Avoidant Immunosuppression in Pediatric Kidney Transplant Recipients

    N. Hayde1, E. Blanchette2, J. Zhang3, M. Chandran2, M. Bock2, S. Galbiati3, T. Blydt-Hansen4

    1Montefiore Medical Center, Bronx, NY, 2Children's Hospital Colorado, Aurora, CO, 3Emmes Corporation, Rockville, MD, 4University of British Columbia, Vancouver, BC, Canada

    *Purpose: With increasing use of potent immunosuppressant (IS) medications, steroid-avoidant (SA) regimens are now commonly used for pediatric kidney transplant recipients (pKTs) to avoid potential…
  • 2022 American Transplant Congress

    Gender Affects the Association Between Serum Creatinine Levels and Clinical Response to Terlipressin in Patients with Hepatorenal Syndrome Type of Acute Kidney Injury

    K. Jamil1, R. Frederick2, S. Pappas3

    1Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ, 2Liver Disease/Hepatology & Transplant Hepatology, California Pacific Medical Center, San Francisco, CA, 3Orphan Therapeutics, LLC, Longboat Key, FL

    *Purpose: Hepatorenal syndrome (HRS)-acute kidney injury (AKI) is a rare and serious complication of cirrhosis, with serum creatinine (SCr) used diagnostically. Women generally have less…
  • 2022 American Transplant Congress

    Creating a Workflow for the Electronic Medical Record Allows Living Donor Liver Transplantation Programs to Track Candidates and Identify Areas for Optimization

    A. Liapakis1, R. Batra1, E. Cohen2, D. Haakinson1, M. Schilsky1, K. Ventura2, D. Mulligan1

    1Yale University School of Medicine, New Haven, CT, 2Yale New Haven Hospital, New Haven, CT

    *Purpose: To provide a pathway to increase living donor liver transplantation (LDLT) opportunities through creation of a simple workflow algorithm embedded within the EPIC electronic…
  • 2022 American Transplant Congress

    Comparison of Immediate-Release Tacrolimus to Envarsus XR on the Development of Donor Specific Antibodies in Kidney Transplant Recipients

    R. A. Arora, C. Kane, K. Lang, M. Kapugi, C. D'Agostino, K. Cunningham, S. H. Park

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Major causes of de novo development of donor specific antibodies (DSA) after kidney transplant include medication noncompliance and immunosuppression minimization or elimination that may…
  • 2022 American Transplant Congress

    Belatacept-Based Maintenance Immunosuppression Promoted Long-Term Antibody-Mediated Rejection Free Graft Survival After Desensitization in Sensitized Multiparous Female Recipients

    M. Manook, I. Anwar, R. Schmitz, Z. Fitch, J. Yoon, A. Jackson, J. Kwun, S. Knechtle

    Duke Transplant Center, Durham, NC

    *Purpose: Amongst sensitized patients awaiting a transplant, females are disproportionately represented. To date, nonhuman primate (NHP) models of transplantation have relied on male animals, sensitized…
  • 2022 American Transplant Congress

    Optimization of Human Liver Organoid Model for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

    Y. Park1, D. Thadasina1, K. Isidan1, K. J. Lopez1, A. Cross-Najafi1, P. Li1, H. Francis2, G. Alpini2, W. Zhang1, B. Ekser1

    1Surgery, Indiana University School of Medicine, Indianapolis, IN, 2Division of Gastroenterology & Hepatology, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The aim of our project is to develop an in vitro 3D human liver organoid (3D-HLO) model for studying nonalcoholic fatty liver disease (NAFLD)…
  • 2022 American Transplant Congress

    Is a Single Dose of Steroids in Adult Living Donor Liver Transplant Safe? – A Cohort Analysis

    M. Nunez, C. Praglin, A. M. Torres, E. Agudelo, H. Braun, C. Huang, S. Syed, J. Roberts, G. Roll

    University of California San Francisco, San Francisco, CA

    *Purpose: Steroids increase morbidity, and steroid avoidance (SA) has been studied in deceased donor liver transplant but, little is known about SA in living donor…
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