ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Cold Pulsatile Perfusion of Deceased Donor Kidneys Substantially Improves Kidney Utilization of Donors After Cardiac Death and Brain Dead Donors with KDPI Greater Than 60%

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine trends in usage of cold pulsatile kidney perfusion and its impact on organ utilization in the United States using the SRTR database.*Methods:…
  • 2022 American Transplant Congress

    Safety and Efficacy of Sodium Glucose Cotransporter-2 Inhibitors in Solid Organ Transplant Recipients

    L. Selznick, J. Contreras, K. Klein, C. Long, R. Hall, S. Bhayana, H. Sweiss

    University Health, San Antonio, TX

    *Purpose: To determine the safety and efficacy of sodium glucose cotransporter-2 inhibitors (SGLT2i) in solid organ transplant.*Methods: This is a retrospective review of adult kidney,…
  • 2022 American Transplant Congress

    Patient Reported Outcomes Following Renal Transplantation: The Future of Holistic Post-Transplant Care

    H. V. Spiers1, S. Frame2, R. Heape3, K. Clark2, A. Altinar2, L. Ross2, H. Wells2, A. Simpson3, J. Chilcot3, L. Hughes3, D. M. Summers1, J. Weinman3, M. Hotopf3, A. J. Cronin2

    1Roy Calne Transplant Unit, Department of Transplantation, Addenbrooke's Hospital, Cambridge, United Kingdom, 2Department of Nephrology and Transplantation, Guy’s and St. Thomas’ Hospital, London, United Kingdom, 3King's College London, London, United Kingdom

    *Purpose: Patients with renal disease prioritise symptoms and functionality over the biochemistry and clinical guidelines, which clinicians traditionally rely on. Whilst kidney transplantation is expected…
  • 2022 American Transplant Congress

    Use of Monoclonal Antibody Casirivimab-Imdevimab for Treatment of COVID-19 in Kidney Transplant Recipients

    A. El Chediak, K. Bloch, R. Forbes, A. Langone, B. P. Concepcion, B. A. Sarrell

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Kidney transplant recipients are at high-risk for severe coronavirus disease 2019 (COVID-19). Studies suggest that intervention with monoclonal antibody (MAB) treatment may decrease hospitalization…
  • 2022 American Transplant Congress

    Acute Tubular Injury and Necrosis Do Not Lead to Meaningful Elevations in Donor-Derived Cell-Free DNA (dd-cfDNA)

    S. R. Allam1, M. Cooper2, D. Kumar3, T. Maw4, A. Wiseman5, P. Chuang6, G. Shekhtman7, N. Agrawal7, J. Zeng7, E. Huang8

    1Medical City Transplant Institute, Fort Worth, TX, 2Medstar Georgetown Transplant Institute, Washington, DC, 3Virginia Commonwealth University, Richmond, VA, 4University of Southern California, Los Angeles, CA, 5Centura Health, Denver, CO, 6Metrolina Nephrology, Charlotte, NC, 7CareDx, Brisbane, CA, 8Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Associations between non-rejection histologic diagnoses and dd-cfDNA have not been extensively characterized. We explored these associations in kidney transplant recipients enrolled in the Kidney…
  • 2022 American Transplant Congress

    Aftercare for Organ Donor Families: A Content Analysis of Organ Procurement Organization Family Services and Educational Materials

    J. Akhtar1, C. Sidoti1, S. Klitenic1, T. Storch2, E. Hughes2, C. Hagan3, A. Helman3, I. Johnson3, K. Vanterpool1, H. Sung1, L. Zeiser1, M. Levan1

    1Johns Hopkins, Baltimore, MD, 2Taylor's Gift Foundation, Coppell, TX, 3Living Legacy Foundation, Baltimore, MD

    *Purpose: Following a sudden and tragic loss, organ donor families’ members experience grief, and may even develop prolonged grief disorder. All US organ procurement organizations…
  • 2022 American Transplant Congress

    Long-Term Effects of Conversion from Calcineurin Inhibitors to Sirolimus for the Recipients with Low Immunological Risk in Renal Allograft

    Q. Wu, J. Chen, D. Cheng, X. Ni, X. Li, K. Xie, W. Jiqiu

    National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University Jinling School of Medicine, Nanjing, China

    *Purpose: To observe the long-term effects and prognosis of conversion from calcineurin inhibitors (CNIs) to sirolimus in biopsy-proven low immunological risk renal transplant recipients (RTRs).*Methods:…
  • 2022 American Transplant Congress

    Association Between De Novo Donor Specific Antibody and Tacrolimus Trough Levels in Long Term Follow Up Renal Transplantation

    N. Fujiyama1, M. Saito2, R. Yamamoto2, R. Sagehashi2, T. Saito2, Y. Aoyama2, K. Numakura2, T. Habuchi2, S. Satoh1

    1Center for Kidney Disease and Transplantation, Akita University Hospital, Akita, Japan, 2Department of Urology, Akita University Graduate School of Medicine, Akita, Japan

    *Purpose: In this study, we aimed to identify the risk factors contributing to the development of donor-specific anti-HLA antibody (DSA) during long-term follow-up of patients…
  • 2022 American Transplant Congress

    Kidney Allograft Injury is Reflected in the DNA Cargo of Urinary Extracellular Vesicles

    I. Sedej1, M. Štalekar2, M. Tušek Žnidarič2, K. Goričar3, N. Kojc4, P. Kogovšek2, V. Dolžan3, M. Lenassi3, M. Arnol1

    1Department of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 2Department of Biotechnology and Systems Biology, National Institute of Biology, Ljubljana, Slovenia, 3Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia, 4Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

    *Purpose: Following cell injury, donor-derived cell-free DNA (ddcfDNA) is increased in the urine of kidney transplant recipients. DNA containing urinary extracellular vesicles (uEVs) are relevant…
  • 2022 American Transplant Congress

    Evaluating Long Term Outcomes in Kidney Transplant Patients with TruGraf Gene Expression and TRAC Dd-cfdna in the TRULO Study

    P. West-Thielke, W. Ally, J. Hickey, L. Stach, J. Fleming, T. Cober, A. Kawano, I. Agboli, C. Miller, J. Holman

    Eurofins Transplant Genomics, Framingham, MA

    *Purpose: The aim of this study is to evaluate long term clinical outcomes in kidney transplant patients undergoing non-invasive rejection monitoring with the OmniGraf® biomarker…
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