ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Mycotic Aneurysm of Transplant Renal Artery Successfully Treated with Arterial Conduit

    Y. Al-Salmay, B. Juengel, J. Kumar, P. Bachul, A. Perez-Guttierez, R. Barth, J. Fung, P. Witkowski

    University of Chicago, Chicago, IL

    *Purpose: Infection in the renal graft hilum may lead to mycotic aneurysm and life threatening bleeding, therefore it often warrants complete excision of the graft.…
  • 2022 American Transplant Congress

    Analysis of Induction Dose and Incidence of CMV Viremia in High Risk (HR; D+/R-) Renal Transplant Recipients

    K. Shimko, M. Pittappilly, R. Chowdhury, H. Karimi, C. Puttarajappa, M. Wijkstrom, R. Mehta

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Depleting induction puts patients at risk of opportunistic infections. Our protocol aims for 5-6mg/kg cumulative dose of antithymocyte globulin(ATG) divided over 4 doses. It…
  • 2022 American Transplant Congress

    Effect of Anti Thymocyte Globulin Induction Therapy in Kidney Transplantation Network Meta-Analysis Using Recent Data

    S. Hwang, J. Song, K. Kim, S. Lee

    Inha University, Incheon, Korea, Republic of

    *Purpose: The use of induction immunosuppressant agents in transplantation is important factors in preserving graft kidney function to prevent rejection. However the question of which…
  • 2022 American Transplant Congress

    Outcomes of Highly-Sensitized, Virtual and Flow Cross-Match Negative Renal Transplant Recipients: A Retrospective Observational Study

    A. Agrawal1, B. Smith1, M. Gandhi2, C. Schinstock1

    1Transplant Nephrology, Mayo Clinic, Rochester, MN, 2Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

    *Purpose: Many highly-sensitized kidney transplant recipients are sensitized from prior transplants, which have been shown to limit graft survival more than pregnancy or blood transfusions.…
  • 2022 American Transplant Congress

    Impact of Mycetoma in Lung Transplant Recipients

    A. Majeed, S. Singh, J. Lum

    CCF, Cleveland, OH

    *Purpose: Mycetoma are uncommon in lung transplant recipients (LTRs) and previous studies describe poor outcomes. We reviewed our experience*Methods: Retrospective review of electronic medical records…
  • 2022 American Transplant Congress

    Biopsy and Blood Gene Expression Profiles Distinguish Injury, Subclinical and Clinical Rejection in Kidney Transplant Recipients

    S. Kurian1, M. Kandpal2, C. Rebello2, C. Marsh1, J. Friedewald2

    1Scripps Health, La Jolla, CA, 2Northwestern University, Chicago, IL

    *Purpose: We analyzed serial gene expression profiles in paired blood and biopsies from kidney transplant recipients phenotyped with a comprehensive clinical algorithm. We compared disease…
  • 2022 American Transplant Congress

    Circulating Antibodies in CMV Viremia in Kidney Transplantation

    T. Sigdel1, P. Velpurisiva1, V. Dharnidharka2, M. M. Sarwal1

    1UCSF, San Francisco, CA, 2Washington University in St. Louis, Saint Louis, MO

    *Purpose: Role of circulating antibodies (Abs) in graft injury outcomes of kidney transplant is reported by us and others. Cytomegalovirus (CMV) is known to contribute…
  • 2022 American Transplant Congress

    Data-Driven Clustering Distinguishes Infection from Rejection During Hospital Admissions Following Pediatric Lung Transplantation

    C. D. Britto1, D. Boyer2, G. Visner3, G. Priebe4, L. Midyat3

    1Department of Pediatrics, Boston Children's Hospital, Boston, MA, 2Division of Pulmonary Medicine, Nationwide Children's Hospital, Ohio, MA, 3Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, 4Department of Anesthesiology, Critical Care and Pain Medicine, Division of Infectious Disease, Boston Children's Hospital, Boston, MA

    *Purpose: When lung transplantation patients are admitted with respiratory symptoms, distinguishing between episodes of infection and rejection is central to determining immunosuppressive management.*Methods: Data comprising…
  • 2022 American Transplant Congress

    Effect of CD8+ Cell Depletion in Treg Mediated Skin Graft Survival

    R. Steiner1, A. M. Weijler1, M. Muckenhuber2, J. Sprent3, T. Wekerle4, N. Pilat1

    1Medical University of Vienna, Vienna, Austria, 2Dept. of General Surgery, Div. of Transplantation, Medical University of Vienna, Vienna, Austria, 3Garvan Institute of Medical Research, Sydney, Australia, 4Vienna Gen Hosp / Medical Univ of Vienna, A-1090 Vienna, Austria

    *Purpose: The selective in vivo expansion and activation of regulatory T cells via administration of interleukin-2 (IL-2) coupled to a specific antibody against IL-2 (IL-2…
  • 2022 American Transplant Congress

    Adenosine A2A Receptor (A2AR) Agonist Apadenoson Promotes Survival in K28-hACE2 Mice and Syrian Hamsters Infected with Sars-CoV-2

    P. Chhabra1, B. Mann2, M. Ma1, S. Feldman3, J. Linden4, K. L. Brayman1

    1Department of Surgery, University of Virginia Health System, Charlottesville, VA, 2Department of Infectious Diseases, University of Virginia Health System, Charlottesville, VA, 3Center for Comparative Medicine, University of Virginia Health System, Charlottesville, VA, 4Department of Nephrology, University of Virginia Health System, Charlottesville, VA

    *Purpose: To determine if Apadenoson or Regadenoson has a therapeutic effect in attenuating hyper-inflammation and improving survival rate in K18-hACE2mice or Syrian hamsters infected with…
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