Am J Transplant, Volume 22, Suppl 3 Archives - Page 167 of 190 - ATC Abstracts

2022 American Transplant Congress
Less is More. Extensive Cardiac Investigations Add Little Value in Waitlisting Patients for Kidney Transplantation
B. Chow¹, M. Khurram², E. Capuano², F. Pugliese², M. Yaqoob², I. Mohamed²
¹Barts and the London School of Medicine and Dentistry, London, United Kingdom, ²Department of Renal and Transplantation, Royal London Hospital, Bart's Health NHS Trust, London, United Kingdom
*Purpose: Extensive cardiac investigations have long been considered necessary to aid decision-making in waitlisting for kidney transplantation. However, the utility and reliability of such comprehensive…
2022 American Transplant Congress
Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients
A. E. Woolley, N. Sharma, G. Zhou, A. Kim, E. Ryan, M. Joyce, H. Goldberg, M. Givertz, M. Mehra, E. Woodcome, V. Durney, S. Marshall, K. Townsend, A. Coppolino, S. Tullius, S. Malek, H. Mallidi, L. Baden, A. Chandraker
Brigham & Women's Hospital, Boston, MA
*Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…
2022 American Transplant Congress
Tabelecleucel (Tab-cel) for Solid Organ (SOT) or Allogeneic Hematopoietic Cell Transplant (HCT) Recipients with Epstein-Barr Virus-Driven Post Transplant Lymphoproliferative Disease (EBV⁺ PTLD) After Failure Of Rituximab (R) ± Chemotherapy (CT) (ALLELE)
S. Prockop¹, A. Beitinjaneh², S. Choquet³, S. Dahiya⁴, R. Dinavahi⁵, R. Farah⁶, L. Gamelin⁵, A. Joshi⁵, A. Mehta⁵, P. Nayak⁵, R. Reshef⁷, G. Satyanarayana⁸, P. Stiff⁹, W. Ye⁵, K. M. Mahadeo¹⁰
¹Boston Children's Hospital/Dana Farber Cancer Institute, Boston, MA, ²University of Miami/Jackson Memorial Hospital, Miami, FL, ³Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Atara Biotherapeutics, South San Francisco, CA, ⁶UPMC Hillman Cancer Center, Pittsburgh, PA, ⁷Columbia University Medical Center, NY, NY, ⁸Ingram Cancer Center, Vanderbilt Health, Nashville, TN, ⁹Loyola University Medical Center, Chicago, IL, ¹⁰MD Anderson Cancer Center, Houston, TX
*Purpose: Tab-cel is an investigational, off-the-shelf, allogeneic EBV-specific T-cell immunotherapy for serious EBV-driven diseases, including EBV+ PTLD. Poor overall survival (OS) in patients (pts) with…
2022 American Transplant Congress
Race Inequity in Liver Transplant Waitlisting: Effect Modification by Psychosocial Factors and the Stanford Integrated Psychosocial Assessment for Transplant
S. Deutsch-Link¹, L. Nephew², E. Weinberg³, R. Weinrieb⁴, M. Serper³
¹Gastroenterology & Hepatology, University of North Carolina, Chapel Hill, NC, ²Gastroenterology & Hepatology, Indiana University, Chapel Hill, NC, ³Gastroenterology & Hepatology, University of Pennsylvania, Philadelphia, PA, ⁴Psychiatry, University of Pennsylvania, Philadelphia, PA
*Purpose: Race inequity in liver transplantation (LT) has been a longstanding area of injustice within the field of hepatology. Information from psychosocial evaluations and The…
2022 American Transplant Congress
Fibroblastic Reticular Cell Subset Transcriptional Reprogramming Differs in Response to Immunity versus Tolerance
L. Li¹, Y. Song¹, M. Shirkey¹, A. Kensiski¹, W. Piao¹, V. Saxena¹, S. Gavzy¹, B. Ma¹, R. Abdi², J. Bromberg¹
¹UMB, Baltimore, MD, ²Harvard University, Boston, MD
*Purpose: Lymph node (LN) fibroblastic reticular cells (FRCs) are central contributors to the LN niche. We hypothesized that FRC subsets reactive to immunity versus tolerance…
2022 American Transplant Congress
Validation of a Hypertension Risk Calculator for Living Kidney Donors
E. S. Helgeson¹, S. Vempati¹, E. F. Palzer¹, G. Mjøen², A. J. Haugen³, A. Matas⁴
¹Division of Biostatistics, University of Minnesota, Minneapolis, MN, ²Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, ³Department of Internal Medicine, Bærum Hospital, Sandvika, Norway, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN
*Purpose: It would be ideal if candidates considering kidney donation understood their long-term risks. Using single-center data (n=4055; median [IQR] f/u: 18 [9-28] yrs), we…
2022 American Transplant Congress
Digital Spatial Profiling of Kidney Allograft Biopsies with Chronic Allograft Dysfunction in African American Transplant Recipients
C. R. Dorr¹, S. A. Elmer¹, B. Wu², B. Guo², J. Czyzyk², G. Crary³, G. Onyeaghala¹, W. Oetting², P. Jacobson², R. B. Mannon⁴, G. Agarwal⁵, J. Maltzman⁶, A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴Medicine, University of Nebraska Medical Center, Omaha, NE, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Stanford University, Palo Alto, CA
*Purpose: Understanding tissue heterogeneity is important to identify the molecular and cellular mechanisms of kidney allograft loss in African American (AA) transplant recipients. Our aim…
2022 American Transplant Congress
Higher Baseline Serum Creatinine Levels AreAssociated with an Increased Incidence of Renal Replacement Therapy in Patients with Hepatorenal Syndrome Type 1 on the Liver Transplant Waitlist
S. N. Sclair¹, A. Befeler², K. Jamil³
¹Hepatology, University Hospitals Cleveland Medical Center & Case Western Reserve University, Cleveland, OH, ²Gastroenterology, Hepatology, Transplant Hepatology, Saint Louis University School of Medicine, St Louis, MO, ³Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ
*Purpose: Pretransplant and posttransplant renal replacement therapy (RRT) is associated with increased morbidity and mortality in liver transplant recipients, including those with Hepatorenal syndrome type…
2022 American Transplant Congress
Pregnancy After Heart Transplant Does Not Negatively Impact Long Term Patient Survival
M. J. Moritz¹, D. Lee², C. Madu², S. Hossain³, L. A. Coscia⁴, S. Rao⁵, S. Constantinescu⁶
¹Surgery, Lehigh Valley Health Network, Allentown, PA, ²Cardiovascular Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL, ³Data Analytics, University of South Florida, Muma College of Business, Tampa, FL, ⁴Transplant Pregnancy Registry International, Philadelphia, PA, ⁵Nephrology, University of Virginia Health System, Charlottesville, VA, ⁶Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA
*Purpose: To evaluate the impact of pregnancy on patient survival in heart transplant recipients (HTRs), we linked the Transplant Pregnancy Registry International (TPRI) dataset with…
2022 American Transplant Congress
Higher Immunogenicity of a Third Heterologous Dose with BNT262b2 Mensanger RNA Vaccine Compared to a Homologous Dose in Kidney Transplant Recipients Fully Vaccinated with Inactivated Whole-Virion CoronaVac Vaccine
L. V. Pouzo¹, M. Nakamura¹, L. A. Viana², E. Lucena¹, M. Jesus¹, G. Bittencourt Pereira Lima¹, J. Medina¹, H. Tedesco¹, M. Cristelli¹
¹Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil, ²Nephrology, Hospital do rim, Sao Paulo, Brazil
*Purpose: This study aims to compare the immunogenicity of a third dose of the heterologous BNT262b2 mRNA vaccine versus the homologous inactivated whole-virion CoronaVac vaccine…