ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Transplant Patients Risk for SARS-CoV-2 Infection Post-2nd Vaccine Dose; We Are Not Home and Dry Yet

    G. Koimtzis1, L. Szabó1, P. Nagaraja1, C. Chalklin1, D. Elker2, A. Asderakis1

    1Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom, 2Cardiff Transplant Unit, University Hosptal of Wales, Cardiff, United Kingdom

    *Purpose: SARS-CoV-2 is associated with high mortality among transplant recipients. Data of transplant patients’ infections post-2nd vaccine dose is not available. The aim of the…
  • 2022 American Transplant Congress

    Adverse Renal Events After BNT162b2 Pfizer/BioNTech COVID-19 Vaccine in Kidney Transplant Recipients

    H. K. Sran1, E. Wong1, M. R. D'Costa2, A. Lim2, Q. Lim2, A. Vathsala1

    1National University of Singapore, Singapore, Singapore, 2National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore

    *Purpose: Adverse events of a novel mRNA vaccine are not well described in Kidney Transplant Recipients(KTR), especially the risk of immune activation or recurrent glomerulonephritis(GN),…
  • 2022 American Transplant Congress

    Changes Of Socioeconomic Status Of Kidney Transplant Recipients And Their Association With Prognosis

    S. Park1, J. Park1, J. Jihoon1, Y. Kim1, Y. Kim2, H. Lee2

    1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: Previous studies showed socioeconomic status affect the level of access to and prognosis of kidney transplantation. Further study is warranted to investigate the changes…
  • 2022 American Transplant Congress

    Mycophenolate Mofetil-Related Diarrhea and Beta-Glucuronidase Activity Following Kidney Transplantation

    G. C. Onyeaghala1, S. Elmer1, D. Schladt1, P. Yang1, M. Wagner2, L. Teigen2, M. Al-Kofahi2, B. Wu2, W. Guan2, C. Staley2, S. Riad2, A. Matas3, R. Remmel2, W. Oetting2, C. R. Dorr1, P. Jacobson4, A. Israni1

    1Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, 2University of Minnesota, Minneapolis, MN, 3University of Minnesota Medical School, Minneapolis, MN, 4Univ of MN, College of Pharmacy, Minneapolis, MN

    *Purpose: The treatment of mycophenolate mofetil (MMF)-related diarrhea in kidney transplants recipients often involves dose reductions, which may result in less effective immunosuppression. We hypothesize…
  • 2022 American Transplant Congress

    Treg Migration and Suppression Require Engagement with Lymphotoxin Beta Receptor on Lymphatic Endothelial Cells to Protect Islet Allografts

    V. Saxena1, W. Piao1, L. Li1, M. WillsonShirkey1, R. Lakhan1, S. Walden2, K. L. Hippen2, B. R. Blazar2, J. S. Bromberg1

    1University of Maryland School of Medicine, Baltimore, MD, 2University of Minnesota, Minneapolis, MN

    *Purpose: Treg sequential migration from graft to draining lymph nodes (dLN) via afferent lymphatics is required for Treg suppressive function. Treg lymphotoxin alpha beta (LTαβ)…
  • 2022 American Transplant Congress

    COVID-19 Vaccination Induces a Poor Interleukin-21 Memory T-cell Response in Kidney Transplant Recipients

    S. R. Malahe1, Y. den Hartog1, R. de Kuiper1, D. Reijerkerk1, D. Geers2, C. H. GeurtsvanKessel2, M. M. Kho1, R. D. de Vries2, M. E. Reinders1, C. C. Baan1

    1Internal Medicine, Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Viroscience, Erasmus MC, Rotterdam, Netherlands

    *Purpose: COVID-19-related morbidity and mortality is high among kidney patients. Several studies recently suggested low humoral and cellular immune responses after two doses of mRNA-1273…
  • 2022 American Transplant Congress

    The Impact of Donor Nephrectomy on the Living Donors Aged 75 Years and Older

    T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, N. Goto, T. Ichimori, S. Narumi, Y. Watarai

    Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan

    *Purpose: Due to the profound organ shortage, number of living donor kidney transplantation (LDKT) from elder living donor (LD) is increasing. However, there has been…
  • 2022 American Transplant Congress

    Longitudinal Mortality Risks and Renal Functional Outcomes in Living Kidney Donors

    K. Hotta1, T. Osawa1, I. Yokota2, T. Inao2, T. Tanabe1, N. Iwahara1, N. Shinohara1

    1Urology, Hokkaido University Hospital, Sapporo, Japan, 2Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    *Purpose: Previous studies have suggested that living kidney donors do not have a higher risk of death or end-stage kidney disease (ESKD) than the general…
  • 2022 American Transplant Congress

    ESRD is Increasing Faster After Living Kidney Donation Than it Does in the Unselected US Population: A New Risk Metric?

    R. W. Steiner

    UCSD School of Medicine, San Diego, San Diego, CA

    *Purpose: ESRD rates increase exponentially both after kidney donation and as the US population ages. Increases in ESRD rates from the first to the second…
  • 2022 American Transplant Congress

    Patient-Reported Barriers to Living Kidney Donor Follow-Up

    B. Orandi, R. Reed, H. Qu, G. Owens, S. Brooks, C. Killian, V. Kumar, S. Sheikh, R. Cannon, C. Lewis, J. Locke

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Despite regulations mandating follow-up laboratory testing for living kidney donors, less than half of transplant centers are in compliance. We sought to understand barriers…
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