2022 American Transplant Congress
Do CMS Oversight and the Systems Improvement Agreement Really Change Institutional Behavior?
University of Alabama Birmingham, Birmingham, AL
*Purpose: A Systems Improvement Agreement (SIA) is a voluntary and binding legal agreement between CMS and a Medicare certified hospital designed to address Condition level…2022 American Transplant Congress
Liver Outcomes and Equity (LOEq) Index: Neighborhood-Level Social Determinants of Health and Waitlist Disparities for Adult Liver Transplantation
University of Southern California, Los Angeles, CA
*Purpose: Impact of neighborhood-level social determinants of health (SDOH) among adult liver transplant (LT) candidates is largely unknown. We constructed a novel index (LOEq) to…2022 American Transplant Congress
NK Cells in Kidney Allograft Antibody-mediated Rejection Display Increased Proliferation, IL-21 Responsiveness, Type-1 Activation, and Cytotoxic Profile
*Purpose: The role of NK cell during antibody-mediated rejection (ABMR) has been previously recognized, but an in-depth characterization of pathways that contribute to such immune…2022 American Transplant Congress
Heterogeneity in Center Practices in Liver Transplantation for Alcohol-Associated Liver Disease in the United States
*Purpose: Alcohol-associated liver disease (ALD) is now the leading indication for liver transplantation (LT) in the United States (US), particularly since LT has emerged as…2022 American Transplant Congress
Resource Expenditure in the Evaluation of Older Donors for Heart Transplant: An Impediment to Donor Pool Expansion?
*Purpose: Using older donors for heart transplant (HT) could alleviate donor scarcity but the resource implications of this strategy - and whether evaluation of older…2022 American Transplant Congress
Development of a Dynamic Map of Peripheral Myeloid Cells Associated with Acute Rejection of Vascularized Composite Tissue Allografts
*Purpose: Myeloid cells are involved in early alloactivation in response to organ allografts and can initiate acute rejection. The heterogeneity of myeloid populations and the…2022 American Transplant Congress
A Signature of Tolerance Which Identifies Subclinical Rejection-Free Patients at One Year After Kidney Transplantation
*Purpose: Spontaneous and rare cases of patients undergoing a functional renal transplant in the absence of immunosuppression represent a particular situation of immune tolerance. We…2022 American Transplant Congress
Perioperative IL-6 Blockade Promotes Intra-Graft Regulation and Prevents Costimulation-Blockade Resistant Rejection
*Purpose: Our group has recently shown that CTLA4-Ig monotherapy leads to limited murine heart allograft survival associated with decreased Treg frequencies and early acute T-cell…2022 American Transplant Congress
Possible Recurrence Must Not Limit Kidney Transplantations for Patients with Focal Segmental Glomerulosclerosis
Istituto Giannina Gaslini, Genova, Italy
*Purpose: Non-genetic forms of Focal Segmental Glomerulosclerosis (FSGS) are at high risk of recurrence after kidney transplant (KT) (55%), when compared to inherited forms (0-4%)…2022 American Transplant Congress
Normothermic Machine Perfusion (NMP) Improves Access to Transplantation for Late Liver Re-Transplant Candidates
*Purpose: Late liver re-transplantation (LLrT) is a complex surgical procedure. Candidates for LLrT spend longer on the waitlist than primary transplant candidates due to selectivity…
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