ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Sarcopenia and Obesity in Renal Transplant Recipients – Effects on Graft and Patient Outcomes

    C. Seet, M. R. Akhtar, L. Clementoni, M. Saoud, R. Shah, I. H. Mohamed, M. A. Khurram

    The Royal London Hospital, London, United Kingdom

    *Purpose: Body composition is associated with prognosis in a range of clinical settings, and patients with renal failure usually have significant comorbidities and are high…
  • 2022 American Transplant Congress

    The Trajectory of Donor-Derived Cell-Free DNA (dd-cfDNA) Complements the Baseline Measurements in Heart Transplant Surveillance for Rejection

    P. Shah1, R. Cheng2, H. Eisen3, B. D. Lowes4, L. Lourenco Jenkins5, Y. Fu5, K. Qu5, J. Teuteberg6, E. DePasquale7

    1Inova Heart and Vascular Institute, Falls Church, VA, 2University of Washington Heart Institute, Seattle, WA, 3Pennsylvania State University, Hershey, PA, 4University of Nebraska Medical Center, Omaha, NE, 5CareDx, Brisbane, CA, 6Stanford University, Stanford, CA, 7University of Southern California, Los Angeles, CA

    *Purpose: Changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the dd-cfDNA…
  • 2022 American Transplant Congress

    Assessment of Humoral and Cellular Immune Responses to Sars Cov-2 Vaccination in Immunocompromised Renal Allograft Recipients

    B. Shin, R. Zhang, T. M. Gadsden, A. Petrosyan, A. Vo, N. Ammerman, S. Sethi, E. Huang, A. Peng, R. Najjar, J. Atienza, I. Kim, S. C. Jordan

    Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: SARS CoV-2 vaccination elicits both robust humoral and T-cell immune responses in healthy individuals. However, a comprehensive assessment of immune responses to SARS-CoV-2 vaccination…
  • 2022 American Transplant Congress

    Adjustment for Race and Ethnicity Does Not Change Transplant Center Outcome Metrics for Liver Recipients

    K. Ross-Driscoll1, J. Gunasti1, J. Harding1, D. Goldberg2, R. Lynch1, R. Patzer1

    1Emory University, Atlanta, GA, 2University of Miami, Miami, FL

    *Purpose: Concerns have been raised about whether transplant center metrics should be adjusted for race and ethnicity given long-standing disparities in outcomes. Proponents of adjustment…
  • 2022 American Transplant Congress

    B Cells Fit for Germinal Center Activity Predict Response to a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients

    E. A. Thompson1, A. H. Karaba1, K. Cascino1, K. Roznik1, T. Chiang1, L. Biavatti1, A. T. Abedon1, J. L. Alejo1, S. L. Klein1, J. N. Blankson1, D. S. Warren1, C. X. Qin1, J. Mitchell1, J. M. Garonzik-Wang2, B. J. Boyarsky1, D. L. Segev1, A. A. Tobian1, W. A. Werbel1, A. L. Cox1, J. R. Bailey1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: While SARS-CoV-2 vaccination has dramatically reduced COVID-19 severity in the general population, fully vaccinated solid organ transplant recipients (SOTRs) demonstrate reduced seroconversion and increased…
  • 2022 American Transplant Congress

    Utility of Porcine Kidneys in Transplantation Model for Training General Surgery Residents

    O. Eletta, V. Putatunda, D. Walls, C. Antwi-Buosiako, B. Perry, N. Maloney Patel, R. Pelletier, A. Bongu

    Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

    *Purpose: We sought to increase the opportunities for general surgery residents to hone their vascular anastomosis skills. Accordingly, we created a kidney transplant model using…
  • 2022 American Transplant Congress

    Racial Hot Spots of Non-Preemptive Kidney Transplant Wait Listing, 2010-2020

    R. B. Buchalter, J. D. Schold

    Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

    *Purpose: Waitlisting kidney transplant patients before dialysis results in better long-term outcomes. Substantial racial disparities exist for preemptive waitlisting and identification of areas where race…
  • 2022 American Transplant Congress

    Development of a Portable Device to Quantify Hepatic Steatosis in Donated Livers Using an AI Algorithm

    S. Klinkachorn1, C. J. Tsoi-A-Sue2, R. R. Narayan2, M. L. Melcher2

    1Computer Science, Stanford, Stanford, CA, 2Surgery, Stanford, Stanford, CA

    *Purpose: An accurate estimation of liver fat content is necessary to predict how a donor liver will function after transplantation. This can be challenging at…
  • 2022 American Transplant Congress

    Angiotensin II-Regulated Proteins Production by Pulmonary Macrophages in Chronic Lung Allograft Dysfunction

    S. Farkona1, A. Duong2, G. Berra2, S. Moshkelgosha2, S. Clotet-Freixas1, S. Juvet2, T. Martinu2, A. Konvalinka1

    1Toronto General Hospital Research Institute and Multi-Organ Transplant, University Health Network, Toronto, ON, Canada, 2Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD), characterized by fibrosis, is the most important cause of mortality after lung transplantation. CLAD mechanisms remain poorly understood and…
  • 2022 American Transplant Congress

    Combined Metagenomic Viral Detection and Donor-Derived Cell-Free DNA Quantification for Solid Organ Transplant Recipients

    R. Sinha1, C. Rebello2, E. Bixler1, A. Al-Turck1, A. Berg1, J. Friedewald2, S. Kleiboeker1

    1Eurofins Viracor, Lees Summit, MO, 2Northwestern University, Chicago, IL

    *Purpose: Solid organ transplant recipients are predisposed to opportunistic infections, and current viral diagnostic methods focus on sensitive detection of single pathogens by qPCR. However,…
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